Abstract: Disclosed are a pharmaceutical composition for anionic drug delivery, and a preparation method therefor, the pharmaceutical composition for anionic drug delivery containing: an anionic drug as an active ingredient; a cationic compound; an amphiphilic block copolymer; and a polylactate, wherein the anionic drug formed a complex with the cationic lipid, and the complex is encapsulated within a micelle structure formed by the amphiphilic block copolymer and the polylactate.

Abstract: The present invention relates to a pharmaceutical composition for preventing or treating autoimmune diseases or tumors, containing, as an active ingredient, a tricyclic compound represented by the following Chemical Formula 1 or a pharmaceutically acceptable salt thereof, and a health food composition for preventing or alleviating autoimmune diseases or tumors, containing the tricyclic compound as an active ingredient, wherein the tricyclic compound represented by Chemical Formula 1 has an excellent inhibitory activity against IRAK4, and thus can be usefully used for the prevention, treatment, or alleviation of autoimmune diseases or tumors.

Abstract: The present invention provides methods for treating or ameliorating metabolic diseases, cholestatic liver diseases, or organ fibrosis, which comprises administering to a subject a therapeutically effective amount of a pharmaceutical composition comprising an isoxazole derivative, a racemate, an enantiomer, or a diastereoisomer thereof, or a pharmaceutically acceptable salt of the derivative, the racemate, the enantiomer, or the diastereoisomer.

Abstract: The present invention relates to isoxazole derivatives, including pharmaceutical compositions and for the preparation of isoxazole derivatives. And more particularly the present invention provided a pharmaceutical composition of isoxazole derivatives for activation of Farnesoid X receptor (FXR, NR1H4).

Abstract: Disclosed are a composition and a method for freeze-drying which allow excellent stability, safety, and efficacy to be exhibited at the time of freeze-drying and reconstituting a composition for anionic drug delivery.

Abstract: The invention relates to a method for selective hydrogenation. More specifically, it relates to a method for selective hydrogenation capable of improving selectivity and reaction efficiency in the hydrogenation process of petroleum resin.

Abstract: The present invention relates to isoxazole derivatives, including pharmaceutical compositions and for the preparation of isoxazole derivatives. And more particularly the present invention provided a pharmaceutical composition of isoxazole derivatives for activation of Farnesoid X receptor (FXR, NR1H4).

Abstract: A method of searching for and providing information about a natural language query having a simple or complex sentence structure, includes: generating a mashup query language having a tree structure in a plurality of levels based on at least one query entity included in a natural language query language via a semantic analysis of the natural language query language; determining whether the plurality of levels are linked through a query entity forming each of the plurality of levels based on attribute information of the mashup query language; searching for data corresponding to the query entity forming each of the plurality of levels from a knowledge database based on a result of the determining, and deriving main information and at least one piece of entity information corresponding to the natural language query language from found data; and laying out a search result screen including the main information and the at least one piece of entity information.

Abstract: Disclosed are a pharmaceutical composition for anionic drug delivery, and a preparation method therefor, the pharmaceutical composition for anionic drug delivery containing: an anionic drug as an active ingredient; a cationic compound; an amphiphilic block copolymer; and a polylactate, wherein the anionic drug formed a complex with the cationic lipid, and the complex is encapsulated within a micelle structure formed by the amphiphilic block copolymer and the polylactate.

Abstract: A display apparatus includes a gamma controller configured to determine whether the target pixel unit is driven in both time division method and space division method based on a plurality of comparison values and a reference condition, and an output controller configured to generate normal gamma-data of the target pixel unit using a normal gamma curve if the plurality of comparison values satisfy the reference condition and to generate high gamma-data and low gamma-data of the target pixel unit using a high gamma curve and a low gamma curve in both time division method and space division method if the plurality of comparison values do not satisfy the reference condition.

Abstract: A display apparatus includes a gamma controller configured to determine whether the target pixel unit is driven in both time division method and space division method based on a plurality of comparison values and a reference condition, and an output controller configured to generate normal gamma-data of the target pixel unit using a normal gamma curve if the plurality of comparison values satisfy the reference condition and to generate high gamma-data and low gamma-data of the target pixel unit using a high gamma curve and a low gamma curve in both time division method and space division method if the plurality of comparison values do not satisfy the reference condition.

Abstract: A method of searching for and providing information about a natural language query having a simple or complex sentence structure, includes: generating a mashup query language having a tree structure in a plurality of levels based on at least one query entity included in a natural language query language via a semantic analysis of the natural language query language; determining whether the plurality of levels are linked through a query entity forming each of the plurality of levels based on attribute information of the mashup query language; searching for data corresponding to the query entity forming each of the plurality of levels from a knowledge database based on a result of the determining, and deriving main information and at least one piece of entity information corresponding to the natural language query language from found data; and laying out a search result screen including the main information and the at least one piece of entity information.

Abstract: There is provided a method of preparing resistant starch with improved processability as one aspect of the present invention, the method comprising: (a) preparing starch modified by a cross-linked bond; and (b) feeding the modified starch to an extruder and then extruding the modified starch to produce an extrudate, in which an extrusion temperature is 50° C. to 200° C. at the time of the extrusion, the ratio of a injection volume of water to a supplying amount of the modified starch, each being supplied into the extruder, is 1.2 ml/g to 2.0 ml/g, and water content in the extrudate is 25 wt % to 50 wt %.

Abstract: The present invention relates to a composition for the diagnosis of mild cognitive impairment, which includes a formulation measuring an mRNA or protein expression level of lipocalin-2 gene, to a kit for the diagnosis of mild cognitive impairment, and to a method for providing information for the diagnosis of mild cognitive impairment using the same. According to the present invention, by using the agent for measuring an mRNA or protein expression level of the lipocalin-2 gene, a patient having mild cognitive impairment can be specifically identified by measuring an expression level of lipocalin-2, which is higher in a group of patients having mild cognitive impairment than in both a normal group and a group of patients having Alzheimer's disease.

Abstract: There is provided a method of preparing resistant starch with improved processability as one aspect of the present invention, the method comprising: (a) preparing starch modified by a cross-linked bond; and (b) feeding the modified starch to an extruder and then extruding the modified starch to produce an extrudate, in which an extrusion temperature is 50° C. to 200° C. at the time of the extrusion, the ratio of a injection volume of water to a supplying amount of the modified starch, each being supplied into the extruder, is 1.2 ml/g to 2.0 ml/g, and water content in the extrudate is 25 wt % to 50 wt %.

Abstract: An organic light emitting device and a manufacturing method thereof is provided. The organic light emitting device includes a first pixel that displays a first color, a second pixel that displays a second color, and a third pixel that displays a third color. The first pixel, the second pixel and the third pixel together form one pixel. Each of the first pixel, second pixel, and third pixel includes a pixel electrode having a transflective electrode, an organic emission layer on the pixel electrode that displays the first color, a common electrode on the third color organic emission layer, and a transparent supplementary member between the pixel electrode and the common electrode.

Abstract: An organic light emitting device according to an exemplary embodiment of the present invention includes a plurality of first, second, and third pixels for displaying different colors, wherein the plurality of first and second pixels are alternately arranged in a first column, the plurality of third pixels are continuously arranged in a second column, and an interval between the third pixels is larger than an interval between the first pixel and the second pixel.

Abstract: An organic light-emitting display device includes a thin film transistor on a substrate, a protective layer and a planarization layer covering the thin film transistor, a pixel electrode connected to the thin film transistor, and a wall positioned on at least a portion of the pixel electrode. The planarization layer includes an aperture which exposes a portion of the pixel electrode. An organic layer is formed on the pixel electrode, and a common electrode is formed on the organic layer. An auxiliary electrode layer is formed to overlap the wall on the common electrode.

Abstract: An organic light emitting device includes a first pixel displaying a first color, a second pixel adjacent to the first pixel and displaying a second color, and a third pixel adjacent to the first pixel or the second pixel and displaying a third color, wherein the first pixel includes a first and second subpixel units that output respective lights having different color characteristics.

Abstract: The present invention provides an electrical processing apparatus and method for electrically processing a display panel having an organic light-emitting layer. The method for electrically processing a display panel having an organic light-emitting layer includes dividing a light-emitting region of the display panel into a plurality of regions; and applying a voltage to at least one region of the plurality of regions where an amplitude of the voltage exceeds an amplitude of a driving voltage of the display panel. The electrical processing apparatus includes a display panel comprising an organic light-emitting layer, a light emitting region, and a plurality of regions, the plurality of regions being defined by dividing the light emitting region; a jig for holding the display panel; and a current supplying portion, wherein the current supplying portion supplies a current individually to each of the plurality of regions.