Abstract: The present disclosure discloses a Bluetooth communication method having audio source scanning mechanism and used in a Bluetooth audio play playback apparatus that includes steps outlined below. A one-to-one connection is established with a Bluetooth communication assistant apparatus. An audio source scanning is performed to generate audio source information according to a scanned Bluetooth audio source apparatus. The audio source information is transmitted to the Bluetooth communication assistant apparatus. A selection command from the Bluetooth communication assistant apparatus is received to select the scanned Bluetooth audio source apparatus as a selected Bluetooth audio source apparatus. Audio data from the selected Bluetooth audio source apparatus is received and playback.

Abstract: A homogeneous assay method that employs a device is provided. In some embodiments, the device contains a pair of plates that can be opened and closed. The sample is placed between two plates. In some embodiments, the thickness of the sample in a closed configuration, the concentration of labels, and amplification factor of the amplification surface are configured to make the label(s) bound on the amplification surface visible without washing away of the unbound labels.

Abstract: A compound of Formula (I), or a pharmaceutically acceptable salt thereof, is provided that has been shown to be useful for treating a PRC2-mediated disease or disorder: wherein R1, R2, R3, R4, R5, and n are as defined herein.

Abstract: The disclosure provides an apparatus, a device, and methods for improving optical analysis of a thin layer of a sample between two plates, particularly for multiple wavelengths.

Abstract: The present disclosure relates to devices, apparatus and methods of improving the accuracy of image-based assay, that uses imaging system having uncertainties or deviations (imperfection) compared with an ideal imaging system. One aspect of the present invention is to add the monitoring marks on the sample holder, with at least one of their geometric and/optical properties of the monitoring marks under predetermined and known, and taking images of the sample with the monitoring marks, and train a machine learning model using the images with the monitoring mark.

Abstract: A multi-mode illumination system, including: a first illumination module; a second illumination module; and a third illumination module, as disclosed herein.

Abstract: A system is described to authorize a transaction using blockchain technology. For example, a transaction authorization system comprises a point of sale (POS) device, a mobile device, and a payment blockchain. The POS device can initiate a transaction by scanning one or more items to be purchased and generating a code comprising a transaction identifier and a total cost of the one or more items. The mobile device can receive the code and can generate a token comprising the transaction identifier, total cost, a selected payment method identifier, and a value that can identify an account of a person associated with the mobile device. The token is sent to a payment blockchain to authorize the transaction.

Abstract: A method of assaying an analyte in a sample is disclosed. The method includes having a sample holder with a sample contact area for contacting a sample with an analyte, having a plurality of calibration structures on the sample contact area of the sample holder, imaging a part of the sample contact area that has the calibration structures, and using an algorithm that includes an image, calibration structures in the image, and artificial intelligence and/or machine learning to identify the analyte and/or determine the analyte concentration.

Abstract: Disclosure relates to a device and a method of using the device for conducting biological and chemical assays on a sample. The device includes two plates. The first plate includes at least a first and a second sample contact areas on its inner surface. Each sample contact area includes spacers having a bottom end fixed on the inner surface and a top end that is distal to the inner surface. The spacers in the first sample contact area differ in height from those in the second sample contact area. The first and second sample contact areas are disposed at different depths along the inner surface of the first plate, so that the top ends of the spacers are aligned on the same flat plane. The method includes depositing the sample onto the sample contact areas, compressing the sample into a thin layer, and analyzing the sample.

Abstract: The disclosure provides a method for identifying a bio-entity including a cell type and count in a sample. The method includes: providing a device comprising a first plate, a second plate, and a patterned structural element; depositing the sample between the first and second plates; reducing the spacing of the first and second plates so that the first and second plates are in a closed configuration to compress the sample into a layer; and imaging the sample to obtain an image; and measuring and analyzing the image against a database generated with a machine learning model to obtain the bio-entity of the sample. The sample can be a blood sample, and the method can be a white blood cell differential test conducted with a mobile phone.

Abstract: Among other things, the present invention is related to devices and methods for improving optical analysis of a thin layer of a sample sandwiched between containing between two plates.

Abstract: One aspect of the present invention is to provide the device and methods for performing an assay that uses the multiplexing of sample thicknesses on the same plate. The sample thickness multiplexing can offer many information that is unavailable in using a single sample thickness.

Abstract: Disclosed are devices and methods for analyzing an analyte, such as white blood cells in liquid samples.

Abstract: One aspect of the present invention is to provide the device and methods for performing an assay that uses the multiplexing of sample thicknesses on the same plate. The sample thickness multiplexing can offer many information that are unavailable in using a single sample thickness.

Abstract: Disclosed is an apparatus and method for imaging: a side-view of a object on a surface, a Contact Angle of a liquid object, the color of an object, or combinations thereof.

Abstract: The present invention relates to the methods, devices, and systems that make bio/chemical sensing (including, not limited to, immunoassay, nucleic assay, electrolyte analysis, etc.) faster, more sensitive, less steps, easy to perform, smaller amount of samples required, less or reduced (or no) needs for professional assistance, and/or lower cost, than many current sensing methods and devices. The present invention also allows a test performed by a smartphone.

Abstract: Disclosed are devices and methods for analyzing an analyte, such as white blood cells in liquid samples.

Abstract: Disclosed is an apparatus and method for imaging: a side-view of a object on a surface, a Contact Angle of a liquid object, the color of an object, or combinations thereof.

Abstract: Among other thing, the present invention provides solution to the problem, particularly, the present invention certain surfaces and certain sample holder to improve the sensitivity, speed, and easy-to-use of an optical signal based assays, such as colorimetric assays or fluorescence assays.