Abstract: A submicron-sized Pickering miniemulsion system stabilized by carbon quantum dots solid nanoparticles for biphasic catalysis is disclosed, which breaks the existing limits for homogenization of the immiscible biphasic system and overcomes the issues for big size of solid particles-stabilized emulsion droplets. A method for producing the carbon quantum dot-based catalysts and a process of establishing the Pickering miniemulsion system for biphasic reaction with enhanced catalytic efficiency are also disclosed. The carbon quantum dot-stabilized Pickering miniemulsion features a pH-responsive behavior, with a reversible transition between the emulsification and demulsification, triggering the easy & facile product separation and emulsifier/catalyst recycling in one reaction vessel.

Abstract: A method and a platform for detecting an immunogenicity of a tumor neoantigen are provided. Specifically, the detection method includes the following steps: culturing human peripheral blood monocytes ex vivo for 13 days, adding an antigenic peptide fragment of human influenza virus and stimulating and activating cytokines, antigenic peptides, and immunoadjuvants during the 13 days, and finally conducting enzyme-linked immunospot (ELISPOT) chromogenic reaction and instrument-based scanning, counting, and analysis to detect the immunogenicity of tumor neoantigen. An application of the detection method and platform in biomedicine is provided. Compared with the prior art, the detection method and platform have advantages and characteristics of a short detection period, high convenience, low consumption of experimental cells, and low detection cost. Therefore, the detection method and platform can be used for ex vivo high-throughput assay for the immunogenicity of the tumor neoantigen.

Abstract: The present disclosure provides an information processing method and apparatus, a terminal, and a storage medium. The information processing method, comprising: in response to a first operation event for a target entity word in displayed content, acquiring target entity word information associated with the target entity word, wherein the target entity word information comprises first information and second information, the first information comprising the meaning of the target entity word, and the second information comprising a communication identifier of a communication group or contact associated with the target entity word; and displaying the target entity word information. According to the present disclosure, the meaning of the target entity word is displayed, and the communication group or contact associated with the target entity word is displayed, such that the user can quickly define the group or contact associated with the target entity word.

Abstract: The present disclosure describes therapies comprising a PD-1 axis binding antagonist, wherein a sample from the patient has been pre-determined to have certain biomarkers.

Abstract: Compositions and methods are provided for modifying the expression or activity of CXorf67 in order to reduce the activity of PRC2. Increased expression of CXorf67 was identified in certain cancers, including PFA ependymomas. Thus, provided herein are methods for reducing PRC2 activity in order to treat cancer. The methods and compositions can be used to treat symptoms cancer or to screen for compounds useful in decreasing PRC2 activity and treating cancer. Further provided are methods of identifying subjects at an increased risk of developing cancer by measuring the expression or activity of CXorf67 or the mutation of specific sites within CXorf67.

Abstract: An optical recoding carrier and an information recording method applying an amplitude shift keying (ASK) method or further a DC-biased ASK method are provided, wherein at least one periodically undulated section and at least one non-periodically undulated section are formed on the optical recording carrier to indicate specific information. The information recording method can be embodied as an addressing method of an optical disk for recording address information of tracks of the optical disk. A continuous track structure is provided on the optical recording carrier to save the available recording space and improve the information reading precision of the optical recording carrier. Furthermore, a signal generating apparatus and an information reading apparatus applied in the information recording method are provided.

Abstract: A technique controls the capacity of a virtual concatenation group (VCG) carried on a SONET path of a data network. Efficient control of VCG capacity is provided by emulating aspects of a Link Capacity Adjustment Scheme (LCAS) protocol in software. A hardware poller facility is employed to manage the status and state of the VCG, as well as members belonging to the VCG. The hardware poller contains one or more VCG state machines (VSMs) and member state machines (MSMs) configured to maintain the status and states of the VCGs and their members.

Abstract: A device for determining dimensions of a workpiece includes a locating apparatus, a determining apparatus and a main processor. The locating apparatus includes a locating board supporting workpieces and defining at least one detecting aperture therethrough. The determining apparatus includes a detecting module, the detecting module includes at least one laser detector, each laser detector includes a laser emitter and a laser receiver respectively mounted on two opposite sides of the locating board. The main processor is connected to the locating apparatus and the determining apparatus, the laser emitter emits laser beams traveling through the detecting aperture and received by the laser receiver, and the main processor determines the dimension of the workpiece according to the dimension of parts on the laser receiver shielded by the workpiece.

Abstract: A measuring system (100) for flatness degree measurement includes a measuring instrument (10) and a processing device (20). The measuring instrument has a base (12), a guide column (14), a sliding member (16), a digital micrometer (18) and a holding member (19). The guide column is vertically attached to the base. The sliding member is moveably attached to the guide column. The digital micrometer is firmly fastened to the sliding member. The holding member is configured for fixing a workpiece (40) and has a reference-standard surface formed thereon. The processing device electronically connects with the digital micrometer. The processing device receives a plurality of measured values from the digital micrometer and displays a testing result after processing the measured values.

Abstract: A device for determining dimensions of a workpiece includes a locating apparatus, a determining apparatus and a main processor. The locating apparatus includes a locating board supporting workpieces and defining at least one detecting aperture therethrough. The determining apparatus includes a detecting module, the detecting module includes at least one laser detector, each laser detector includes a laser emitter and a laser receiver respectively mounted on two opposite sides of the locating board. The main processor is connected to the locating apparatus and the determining apparatus, the laser emitter emits laser beams traveling through the detecting aperture and received by the laser receiver, and the main processor determines the dimension of the workpiece according to the dimension of parts on the laser receiver shielded by the workpiece.

Abstract: An optical recoding carrier and an information recording method applying an amplitude shift keying (ASK) method or further a DC-biased ASK method are provided, wherein at least one periodically undulated section and at least one non-periodically undulated section are formed on the optical recording carrier to indicate specific information. The information recording method can be embodied as an addressing method of an optical disk for recording address information of tracks of the optical disk. A continuous track structure is provided on the optical recording carrier to save the available recording space and improve the information reading precision of the optical recording carrier. Furthermore, a signal generating apparatus and an information reading apparatus applied in the information recording method are provided.

Abstract: A measuring system (100) for flatness degree measurement includes a measuring instrument (10) and a processing device (20). The measuring instrument has a base (12), a guide column (14), a sliding member (16), a digital micrometer (18) and a holding member (19). The guide column is vertically attached to the base. The sliding member is moveably attached to the guide column. The digital micrometer is firmly fastened to the sliding member. The holding member is configured for fixing a workpiece (40) and has a reference-standard surface formed thereon. The processing device electronically connects with the digital micrometer. The processing device receives a plurality of measured values from the digital micrometer and displays a testing result after processing the measured values.

Abstract: A method for measuring a surface structure of a near-field object is provided. A light source produces at least a first light beam and a second light beam; guiding the first light beam and the second light beam to enter the SIL for interacting with the object surface. This method can be used in, for example, a near-field optical disc storage system, wherein reflection intensities of the first and second light beams are used to measure two distances between the SIL and the optical disc at two positions corresponding to the first and second light beams. A surface structure, such as a tilt angle or an average distance between the disc and the SIL or disc roughness, is obtained by analyzing the above-mentioned positions and distances. The first and second light beams are produced, for example, by a diffraction technology or by a single laser diode with multiple beams.