Abstract: An ablation apparatus places electrodes at the perimeter of a cavity. In an embodiment, the alternating electric field is used to expose the cavity to enough energy to ablate the cavity. In an embodiment, two modes are used to expose different regions of the cavity to different amounts of power for so that the thermal effect is more uniform. In an embodiment, the electrodes have a relatively large surface area so as to avoid charring the cavity, but are shaped so as to fit within a body orifice. For example, the diameter of the sheathed housing the electrodes during penetration may be only 5.5 mm.

Abstract: An ablation apparatus places electrodes at the perimeter of a cavity. In an embodiment, the alternating electric field is used to expose the cavity to enough energy to ablate the cavity. In an embodiment, two modes are used to expose different regions of the cavity to different amounts of power so that the thermal effect is more uniform. In an embodiment, the electrodes have a relatively large surface area so as to avoid charring the cavity, but are shaped so as to fit within a body orifice.

Abstract: An ablation apparatus places electrodes at the perimeter of a cavity. In an embodiment, the alternating electric field is used to expose the cavity to enough energy to ablate the cavity. In an embodiment, two modes are used to expose different regions of the cavity to different amounts of power for so that the thermal effect is more uniform. In an embodiment, the electrodes have a relatively large surface area so as to avoid charring the cavity, but are shaped so as to fit within a body orifice. For example, the diameter of the sheathed housing the electrodes during penetration may be only 5.5 mm.

Abstract: An ablation apparatus places electrodes at the perimeter of a cavity. In an embodiment, the alternating electric field is used to expose the cavity to enough energy to ablate the cavity. In an embodiment, two modes are used to expose different regions of the cavity to different amounts of power so that the thermal effect is more uniform. In an embodiment, the electrodes have a relatively large surface area so as to avoid charring the cavity, but are shaped so as to fit within a body orifice.

Abstract: An ablation apparatus places electrodes at the perimeter of a cavity. In an embodiment, the alternating electric field is used to expose the cavity to enough energy to ablate the cavity. In an embodiment, two modes are used to expose different regions of the cavity to different amounts of power for so that the thermal effect is more uniform. In an embodiment, the electrodes have a relatively large surface area so as to avoid charring the cavity, but are shaped so as to fit within a body orifice. For example, the diameter of the sheathed housing the electrodes during penetration may be only 5.5 mm.

Abstract: A stent-graft includes a short tube graft and patch located inside of a primary graft. The patch forms a smooth and reliably sealed transition between the primary graft and the short tube graft. Accordingly, the disruption to fluid, e.g., blood, flowing through the lumen of the primary graft by the short tube graft is minimal. Further, the patch supports the inner end of the short tube graft. Thus, the patch, the short tube graft and the primary graft form a stable three-dimensional structure.

Abstract: A stent graft system and method of use includes a stent graft for fixation at an attachment site with graft material defining at least one opening having an opening perimeter; a support attached to the graft material; a guide rail attached around the opening perimeter; and a helical anchor having a plurality of coils with a point at one end. The plurality of coils are rotatable around the guide rail to cause the pointed end of the coils to penetrate the graft material and the adjacent tissue in contact with the stent graft to sew the stent graft to the attachment site.

Abstract: An ablation apparatus places electrodes at the perimeter of a cavity. In an embodiment, the alternating electric field is used to expose the cavity to enough energy to ablate the cavity. In an embodiment, two modes are used to expose different regions of the cavity to different amounts of power for so that the thermal effect is more uniform. In an embodiment, the electrodes have a relatively large surface area so as to avoid charring the cavity, but are shaped so as to fit within a body orifice. For example, the diameter of the sheathed housing the electrodes during penetration may be only 5.5 mm.

Abstract: A prosthesis delivery system comprises a tip having a lumen, a first end and a second end; a sleeve coupled to the tip second end; a spindle comprising a spindle body and a plurality of projections extending radially outward from the spindle body, each projection having a first edge and a second edge, the first edge facing the tip and the second edge extending from the first edge, being angled toward the tip first end, and extending toward the sleeve; and endoprosthesis having an undulating spring with a plurality of crown portions having apices, where the crown portions extend over at least one of the first or second edges and the sleeve radially constrains the apices.

Abstract: A stent graft fixation system and method including a stent graft for fastening to a fixation point in a body lumen, the stent graft including a stent; a graft material supported by the stent and having a fixation region; and a guide suture joined to the graft material in the fixation region. The guide suture has a length selected to extend from the fixation point to outside of the body lumen.

Abstract: A stent graft system includes a first stent graft having a first end and a second end opposing the first end. The system further includes a second stent graft in fluid communication with the first stent graft. The second stent graft defines a lumen a third end in fluid communication with the second end. The second stent graft further includes a fourth end opposing the third end, and at least a first sleeve and second sleeve extending radially therefrom and in fluid communication with the lumen, The first sleeve is radially offset from the second sleeve. Each of the first sleeve and second sleeve comprises a flexible material configured to evert between a first position such that the sleeve is positioned within the lumen and a second position such that the sleeve is positioned exterior to the lumen. The system further includes a third stent graft.

Abstract: A tubular prosthesis comprises a tubular graft; and an undulating stent having a plurality of apexes, a first end defined at least in part by a first group of the apexes, and a second end defined at least in part by a second group of the apexes, the first group of apexes being pivotally attached to the tubular graft so as to form a plurality of circumferentially arranged hinges about which the stent can pivot so that the second group of apexes can move between a position where they are inside the tubular graft and a position where they are outside the tubular graft.

Abstract: A stent graft system and method of use includes a stent graft for fixation at an attachment site with graft material defining at least one opening having an opening perimeter; a support attached to the graft material; a guide rail attached around the opening perimeter; and a helical anchor having a plurality of coils with a point at one end. The plurality of coils are rotatable around the guide rail to cause the pointed end of the coils to penetrate the graft material and the adjacent tissue in contact with the stent graft to sew the stent graft to the attachment site.

Abstract: An endostapler delivery system includes a biasing mechanism to offset or counter forces generated by a stapling device and therefore prevent the stapling device from moving during the firing of the staple. The delivery system includes a catheter having at least one lumen extending there through for receiving the stapling device. The biasing mechanism is an expandable biasing cage having a dome or semi-circular expanded shape provided at the distal portion of the catheter. When expanded, the biasing cage does not block or occlude a vessel, thereby allowing blood flow to continue during the stapling procedure. The biasing cage may include a plurality of ribbons or strands that extend generally parallel to the blood flow when expanded in situ, a mesh or braided structure, or a plurality of ribbons or strands that extend generally parallel to the blood flow when expanded in situ and a mesh or braided structure placed over the plurality of ribbons.

Abstract: An endostapler delivery system includes a biasing mechanism to offset or counter forces generated by a stapling device and therefore prevent the stapling device from moving during the firing of the staple. The delivery system includes a catheter having at least one lumen extending there through for receiving the stapling device. The biasing mechanism is an expandable biasing cage having a dome or semi-circular expanded shape provided at the distal portion of the catheter. When expanded, the biasing cage does not block or occlude a vessel, thereby allowing blood flow to continue during the stapling procedure. The endostapler delivery system further includes a steering wire that can be used to bend the catheter shaft.

Abstract: A cryoablation system including a cannula having a proximal end, a distal end, and a longitudinal axis, an expandable balloon extending from the distal end of the cannula and fluidly connected to a source of heat transfer fluid by at least one fluid path, a pump for circulating the heat transfer fluid into and out of the balloon, a probe handle coupled to the proximal end of the cannula and in fluidic communication with the balloon through the cannula, and a heat exchanger for varying the temperature of the heat transfer fluid, wherein the heat exchanger is fluidly connected to a secondary refrigerant source. The heat exchanger may be positioned within the probe handle, within the cannula, or at least partially within the balloon. The heat transfer fluid of this cryoablation system preferably has a freezing point lower than about ?110° C. and a boiling point greater than about 50° C.

Abstract: Endovascular fastener delivery apparatus comprises a flexible elongated member having a proximal end and a distal end and being configured and adapted to be endolumenally advanced through human vasculature, a flexible pusher member slidably coupled to the elongated member, and a plurality of serially aligned clip carriers secured to the pusher member, each clip carrier comprising a spring element and having a leading end adapted to seat a fastener and a trailing end fixedly secured to the pusher member. In one embodiment, a plurality of bridge clip fasteners are endolumenally advanced to a site in a lumen in a human body and the fasteners are passed from an inner surface of the prosthesis through the prosthesis and a wall of the lumen to secure the prosthesis to the lumen wall.

Abstract: A cryoablation system including a cannula having a proximal end, a distal end, and a longitudinal axis, an expandable balloon extending from the distal end of the cannula and fluidly connected to a source of heat transfer fluid by at least one fluid path, a pump for circulating the heat transfer fluid into and out of the balloon, a probe handle coupled to the proximal end of the cannula and in fluidic communication with the balloon through the cannula, and a heat exchanger for varying the temperature of the heat transfer fluid, wherein the heat exchanger is fluidly connected to a secondary refrigerant source. The heat exchanger may be positioned within the probe handle, within the cannula, or at least partially within the balloon. The heat transfer fluid of this cryoablation system preferably has a freezing point lower than about ?110° C. and a boiling point greater than about 50° C.

Abstract: An electrode device adapted for use in medical devices, such as tissue ablation apparatus, includes a sheet of flexible fabric including at least one surface electrode formed as part of the fabric. More particularly, the sheet is made from a plurality of filaments. At least some of the filaments are made at least partially from an electrically conductive material and cooperate so as to form the electrode. The filaments are formed into a plurality of yarns which are interwoven to form the sheet.

Abstract: A stent graft fixation system and method including a stent graft for fastening to a fixation point in a body lumen, the stent graft including a stent; a graft material supported by the stent and having a fixation region; and a guide suture joined to the graft material in the fixation region. The guide suture has a length selected to extend from the fixation point to outside of the body lumen.