Abstract: Provided are a residual image detection method and apparatus of a display panel, and a display device. The method includes: controlling a display panel to display a chessboard picture for a preset duration, controlling the display panel to display a pure color picture having a third grayscale, the pure color picture includes multiple pure color sub-pictures, and each of pure color sub-picture includes a middle area and multiple edge areas surrounding the middle area; detecting a luminance of each of the multiple edge areas in the pure color picture; and calculating the residual image quantization value of each of the multiple edge areas according to the luminance of each of the multiple edge areas and a formula, and determining a residual image quantization value of the display panel according to residual image quantization values of the multiple edge areas.