Patents by Inventor Jialan Shi

Jialan Shi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and assays for factor VIII activity
    Patent number: 11067572
    Abstract: The methods and compositions described herein relate to the measurement of factor VIII (fVIII) levels and/or activity.
    Type: Grant
    Filed: October 29, 2018
    Date of Patent: July 20, 2021
    Assignees: President and Fellows of Harvard College, The U.S. Government as Represented by The Department of Veterans Affairs
    Inventors: Gary Eugene Gilbert, Jialan Shi, Valerie A. Novakovic
  • METHODS AND ASSAYS FOR FACTOR VIII ACTIVITY
    Publication number: 20190064159
    Abstract: The methods and compositions described herein relate to the measurement of factor VIII (fVIII) levels and/or activity.
    Type: Application
    Filed: October 29, 2018
    Publication date: February 28, 2019
    Applicants: PRESIDENT AND FELLOWS OF HARVARD COLLEGE, THE U.S. GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS
    Inventors: Gary Eugene Gilbert, Jialan Shi, Valerie A. Novakovic
  • LONG TERM STORAGE AND PRESERVATION OF PLATELETS
    Publication number: 20190045776
    Abstract: Provided herein, inter alia, are compositions and methods for preserving platelets in a lesion-free and functional state during extended storage periods of up to 15 days as well as methods and kits for utilizing the same. In contrast to currently available compositions and techniques for preserving platelets, platelets stored in the compositions disclosed herein are characterized by a marked decrease in “storage-lesions,” which are associated with attenuated hemostatic function. During platelet storage, the compositions disclosed herein (1) maintain and/or restore platelet energy states and morphology; (2) maintain active metabolism and buffering; (3) preserve and/or promote nitric oxide production; and (4) prevent microparticle formation, aggregation and activation during storage. As such, long term preservation in the compositions described herein produce platelets that are fully functional and lesion-free.
    Type: Application
    Filed: June 9, 2016
    Publication date: February 14, 2019
    Applicants: PRESIDENT AND FELLOWS OF HARVARD COLLEGE, PRESIDENT AND FELLOWS OF HARVARD COLLEGE, PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Hemant THATTE, Jialan SHI
  • Methods and assays for factor VIII activity
    Patent number: 10114017
    Abstract: The methods and compositions described herein relate to the measurement of factor VIII (fVIII) levels and/or activity.
    Type: Grant
    Filed: November 11, 2014
    Date of Patent: October 30, 2018
    Assignees: PRESIDENT AND FELLOWS OF HARVARD COLLEGE, THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS
    Inventors: Gary Eugene Gilbert, Jialan Shi, Valerie A. Novakovic
  • METHODS AND ASSAYS FOR FACTOR VIII ACTIVITY
    Publication number: 20160291008
    Abstract: The methods and compositions described herein relate to the measurement of factor VIII (fVIII) levels and/or activity.
    Type: Application
    Filed: November 11, 2014
    Publication date: October 6, 2016
    Applicants: PRESIDENT AND FELLOWS OF HARVARD COLLEGE, THE U.S. GOVERNMENT AS REPRESENTED BY THE DEPARTME NT OF VETERANS AFFAIRS
    Inventors: Gary Eugene GILBERT, Jialan SHI, Valerie A. NOVAKOVIC
  • ORAL SYRINGES
    Publication number: 20160279031
    Abstract: An oral dispensing device comprises a main body for holding liquid and a guard, the main body being straight, elongated and having a longitudinal axis, and capable of dispensing the held liquid from one end, and the guard being set upon the main body with a front portion of the main body protruding from the front of the guard. The guard being shaped such that when the front portion is placed in a mouth of a subject, the guard lies against the front of a face of the subject, such that if the front of the face of the subject is consider as a plane, the longitudinal axis of the liquid holding body is inclined to the plane of the face.
    Type: Application
    Filed: November 17, 2014
    Publication date: September 29, 2016
    Applicant: BABYHAPPY LTD.
    Inventors: Dorota Dyk, Jialan Shi, Valerie A. Vovakovic
  • Method for detecting the presence of a phospholipid
    Patent number: 7771956
    Abstract: A method, kit and probe for detecting the presence of a phospholipid, such as phosphatidylserine, in a biological material is provided. A binding agent including lactadherin, a fragment of lactadherin, a functional equivalent of lactadherin, or a functional equivalent of a fragment of lactadherin, is used to detect the presence of any phospholipid.
    Type: Grant
    Filed: June 30, 2004
    Date of Patent: August 10, 2010
    Assignees: Brigham & Women's Hospital, Inc., United States of America Department of Veterans Affairs
    Inventors: Gary E. Gilbert, Jialan Shi, Christian W. Heegaard, Jan T. Rasmussen
  • Method, composition and kit for detecting phosphatidylserine (PS) on cell membranes
    Publication number: 20100168401
    Abstract: A method, composition and kit for detecting the presence of a phospholipid, such as phosphatidylserine, on a cell membrane is provided. A binding agent including lactadherin, a fragment of lactadherin, a functional equivalent of lactadherin, or a functional equivalent of a fragment of lactadherin, is used to detect the presence of any phospholipid.
    Type: Application
    Filed: March 8, 2010
    Publication date: July 1, 2010
    Inventors: Gary E. Gilbert, Jialan Shi, Christian W. Heegaard, Jan T. Rasmussen
  • Method, Composition and Kit for Detecting Phosphatidylserine (Ps) on Cell Membranes
    Publication number: 20070249734
    Abstract: A method, composition and kit for detecting the presence of a phospholipid, such as phosphatidylserine, on a cell membrane is provided. A binding agent including lactadherin, a fragment of lactadherin, a functional equivalent of lactadherin, or a functional equivalent of a fragment of lactadherin, is used to detect the presence of any phospholipid.
    Type: Application
    Filed: June 30, 2004
    Publication date: October 25, 2007
    Applicants: THE BRIGHAM & WOMEN'S HOSPITAL, INC., U.S. DEPT. OF VETERANS AFFAIRS
    Inventors: Gary Gilbert, Jialan Shi, Christian Heegaard, Jan Rasmussen