Patents by Inventor Jiali Li
Jiali Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20120109659Abstract: The invention provides a compensation method for audio frame loss in a MDCT domain, the method comprising: when a frame currently lost is a Pth frame, obtaining a set of frequencies to be predicted, and for each frequency in the set, using phases and amplitudes of a plurality of frames before a (P?1)th frame in a MDCT-MDST domain to predict a phase and an amplitude of the Pth frame, and using the predicted phase and amplitude to obtain a MDCT coefficient of the Pth frame at each corresponding frequency; for a frequency outside the set, using MDCT coefficients of a plurality of frames before the Pth frame to calculate a MDCT coefficient value of the Pth frame at the frequency; performing an IMDCT for the MDCT coefficients of the Pth frame to obtain a time domain signal of the Pth frame.Type: ApplicationFiled: February 25, 2010Publication date: May 3, 2012Applicant: ZTE CORPORATIONInventors: Ming Wu, Zhibin Lin, Ke Peng, Zheng Deng, Jing Lu, Xiaojun Qiu, Jiali Li, Guoming Chen, Hao Yuan, Kaiwen Liu
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Publication number: 20110159601Abstract: The invention features methods for evaluating the conformation of a polymer, for example, for determining the conformational distribution of a plurality of polymers and to detect binding or denaturation events. The methods employ a nanopore which the polymer, e.g., a nucleic acid, traverses. As the polymer traverses the nanopore, measurements of transport properties of the nanopore yield data on the conformation of the polymer.Type: ApplicationFiled: December 6, 2010Publication date: June 30, 2011Inventors: Jene A. Golovchenko, Jiali Li, Derek Stein, Marc H. Gershow
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Patent number: 7846738Abstract: The invention features methods for evaluating the conformation of a polymer, for example, for determining the conformational distribution of a plurality of polymers and to detect binding or denaturation events. The methods employ a nanopore which the polymer, e.g., a nucleic acid, traverses. As the polymer traverses the nanopore, measurements of transport properties of the nanopore yield data on the conformation of the polymer.Type: GrantFiled: August 16, 2004Date of Patent: December 7, 2010Assignee: President and Fellows of Harvard CollegeInventors: Jene A. Golovchenko, Jiali Li, Derek Stein, Marc H. Gershow
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Patent number: 7258838Abstract: A solid state nanopore device including two or more materials and a method for fabricating the same. The device includes a solid state insulating membrane having an exposed surface, a conductive material disposed on at least a portion of the exposed surface of the solid state membrane, and a nanopore penetrating an area of the conductive material and at least a portion of the solid state membrane. During fabrication a conductive material is applied on a portion of a solid state membrane surface, and a nanopore of a first diameter is formed. When the surface is exposed to an ion beam, material from the membrane and conductive material flows to reduce the diameter of the nanopore. A method for evaluating a polymer molecule using the solid state nanopore device is also described. The device is contacted with the polymer molecule and the molecule is passed through the nanopore, allowing each monomer of the polymer molecule to be monitored.Type: GrantFiled: February 14, 2003Date of Patent: August 21, 2007Assignee: President and Fellows of Harvard CollegeInventors: Jiali Li, Derek M. Stein, Gregor M. Schurmann, Gavin M. King, Jene Golovchenko, Daniel Branton, Michael Aziz
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Publication number: 20070172386Abstract: A solid state nanopore device including two or more materials and a method for fabricating the same. The device includes a solid state insulating membrane having an exposed surface, a conductive material disposed on at least a portion of the exposed surface of the solid state membrane, and a nanopore penetrating an area of the conductive material and at least a portion of the solid state membrane. During fabrication a conductive material is applied on a portion of a solid state membrane surface, and a nanopore of a first diameter is formed. When the surface is exposed to an ion beam, material from the membrane and conductive material flows to reduce the diameter of the nanopore. A method for evaluating a polymer molecule using the solid state nanopore device is also described. The device is contacted with the polymer molecule and the molecule is passed through the nanopore, allowing each monomer of the polymer molecule to be monitored.Type: ApplicationFiled: February 14, 2003Publication date: July 26, 2007Inventors: Jiali Li, Derek Stein, Gregor Schurmann, Gavin King, Jene Golovchenko, Daniel Branton, Michael Aziz
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Publication number: 20070141025Abstract: Provided is a cancer therapeutic agent comprising a cancer targeting molecule linked to a liver-expressed chemokine (LEC). In one embodiment, the cancer targeting molecule is an antibody that targets cancer cells or tumors in vivo. The cancer targeting molecule is associated non-covalently or covalently with LEC. The cancer therapeutic agents of the invention are useful for the treatment of cancer in an individual by reducing the size of a tumor or inhibiting the growth of cancer cells in an individual and/or by inhibiting the development of metastasis. The effectiveness of the therapy using the LEC cancer therapeutic agents can be increased by reducing the activity of immunoregulatory T cells and/or by adoptively transferring immune T cells.Type: ApplicationFiled: February 13, 2007Publication date: June 21, 2007Inventors: Alan Epstein, Jiali Li, Peisheng Hu
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Patent number: 7118657Abstract: For controlling a physical dimension of a solid state structural feature, a solid state structure is provided, having a surface and having a structural feature. The structure is exposed to a first periodic flux of ions having a first exposure duty cycle characterized by a first ion exposure duration and a first nonexposure duration for the first duty cycle, and then at a second periodic flux of ions having a second exposure duty cycle characterized by a second ion exposure duration and a second nonexposure duration that is greater than the first nonexposure duration, for the second duty cycle, to cause transport, within the structure including the structure surface, of material of the structure to the structural feature in response to the ion flux exposure to change at least one physical dimension of the feature substantially by locally adding material of the structure to the feature.Type: GrantFiled: October 28, 2003Date of Patent: October 10, 2006Assignee: President and Fellows of Harvard CollegeInventors: Jene A. Golovchenko, Derek M. Stein, Jiali Li
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Publication number: 20060003458Abstract: The invention features methods for evaluating the conformation of a polymer, for example, for determining the conformational distribution of a plurality of polymers and to detect binding or denaturation events. The methods employ a nanopore which the polymer, e.g., a nucleic acid, traverses. As the polymer traverses the nanopore, measurements of transport properties of the nanopore yield data on the conformation of the polymer.Type: ApplicationFiled: August 16, 2004Publication date: January 5, 2006Inventors: Jene Golovchenko, Jiali Li, Derek Stein, Marc Gershow
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Publication number: 20050006224Abstract: For controlling a physical dimension of a solid state structural feature, a solid state structure is provided, having a surface and having a structural feature. The structure is exposed to a first periodic flux of ions having a first exposure duty cycle characterized by a first ion exposure duration and a first nonexposure duration for the first duty cycle, and then at a second periodic flux of ions having a second exposure duty cycle characterized by a second ion exposure duration and a second nonexposure duration that is greater than the first nonexposure duration, for the second duty cycle, to cause transport, within the structure including the structure surface, of material of the structure to the structural feature in response to the ion flux exposure to change at least one physical dimension of the feature substantially by locally adding material of the structure to the feature.Type: ApplicationFiled: October 28, 2003Publication date: January 13, 2005Applicant: President and Fellows of Harvard CollegeInventors: Jene Golovchenko, Derek Stein, Jiali Li
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Publication number: 20040228836Abstract: Provided is a cancer therapeutic agent comprising a cancer targeting molecule linked to a liver-expressed chemokine (LEC). In one embodiment, the cancer targeting molecule is an antibody that targets cancer cells or tumors in vivo. The cancer targeting molecule is associated non-covalently or covalently with LEC. The cancer therapeutic agents of the invention are useful for the treatment of cancer in an individual by reducing the size of a tumor or inhibiting the growth of cancer cells in an individual and/or by inhibiting the development of metastasis. The effectiveness of the therapy using the LEC cancer therapeutic agents can be increased by reducing the activity of immunoregulatory T cells and/or by adoptively transferring immune T cells.Type: ApplicationFiled: February 13, 2004Publication date: November 18, 2004Applicant: University of Southern CaliforniaInventors: Alan L. Epstein, Jiali Li, Peisheng Hu
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Patent number: 6783643Abstract: A solid state structure having a surface is provided and exposed to a flux, F, of incident ions under conditions that are selected based on: ∂ ∂ t ⁢ C ⁡ ( r , t ) = F ⁢ ⁢ Y 1 + D ⁢ ∇ 2 ⁢ C - C τ trap - F ⁢ ⁢ C ⁢ ⁢ &sigmType: GrantFiled: June 27, 2002Date of Patent: August 31, 2004Assignee: President and Fellows of Harvard CollegeInventors: Jene A. Golovchenko, Daniel Branton, Michael J. Aziz, Jiali Li, Derek M. Stein, Ciaran J. McMullan
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Publication number: 20030066749Abstract: A solid state structure having a surface is provided and is exposed to a flux, F, of incident ions.Type: ApplicationFiled: June 27, 2002Publication date: April 10, 2003Applicant: President and Fellows of Harvard CollegeInventors: Jene A. Golovchenko, Daniel Branton, Michael J. Aziz, Jiali Li, Derek M. Stein, Ciaran J. McMullan
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Patent number: 6464842Abstract: There is provided controlled fabrication of a solid state structural feature on a solid state structure by exposing the structure to a fabrication process environment the conditions of which are selected to produce a prespecified feature in the structure. A physical detection species is directed toward a designated structure location during process environment exposure of the structure, and the detection species is detected in a trajectory from traversal of the designated structure location, to indicate changing physical dimensions of the prespecified feature. The fabrication process environment is then controlled in response to the physical species detection to fabricate the structural feature.Type: GrantFiled: June 22, 2000Date of Patent: October 15, 2002Assignee: President and Fellows of Harvard CollegeInventors: Jene A. Golovchenko, Daniel Branton, Derek M. Stein, Ciaran J. McMullan, Jiali Li
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Patent number: 6449472Abstract: A remote convenience system (10) and an associated function remotely control convenience functions at a vehicle (16). A receiver/controller (14), located at the vehicle (16), receives vehicle remote convenience function request signals (30) that convey remote function request messages and controls vehicle systems (e.g., 48, 50, 52, and 68) to perform the remotely requested vehicle functions. The receiver/controller (14) includes a messaging processing portion (110) for providing a signal (e.g., 128/130) to activate an at-vehicle alarm component (e.g., 50/52) and for providing a signal (132) to activate a remote assistance-summoning component (68). A portable transmitter outputs the remote convenience function request signals (30) to cause remote control performance. The transmitter (12) includes a manually actuatable emergency pushbutton switch (94). The switch (94) is actuatable in a first operation mode (e.g.Type: GrantFiled: May 5, 1999Date of Patent: September 10, 2002Assignee: TRW Inc.Inventors: Rahul Dixit, Judy (Jiali) Li, Michael Scott Ogden, James W. Hussey