Abstract: A polypeptide compound having a structure shown in formula I, or a stereoisomer, mixture or pharmaceutically acceptable salt thereof Experimental results show that the polypeptide compound can effectively exhibit high agonistic activity to GHSR-1a.

Abstract: The present disclosure provides an N protein epitope mutation marker for preparing an epitope deletion-marked vaccine strain of type II porcine reproductive and respiratory syndrome virus (PRRSV) and use thereof, belonging to the technical field of biological products. In the mutation marker, one or more amino acids are mutated based on an epitope sequence at positions 92 to 103 of a C-terminal of an N protein of the type II PRRSV; and the epitope mutation marker has an amino acid sequence shown in SEQ ID NO: 1, where X1 is selected from the group consisting of T, P, and A; and X2 is selected from the group consisting of V and A.

Abstract: An apparatus for wireless communication includes a receiver configured to receive a request for data associated with an Internet-of-things (IoT) service session with an IoT cloud server. The apparatus further includes a transmitter configured to transmit, based on receiving the request and prior to transmitting a response to the request, a message indicating a timing parameter associated with availability of the data. The receiver is further configured to receive an uplink grant at a time that is based on the timing parameter, and the transmitter is further configured to transmit the response to the request based on the uplink grant. The response includes at least a subset of the data.

Abstract: Disclosed is a copper-niobium alloy for a medical biopsy puncture needle. A needle core and/or needle tube of the puncture needle are/is made of the copper-niobium alloy. The copper-chromium alloy includes the following components by mass: 5?Nb?15 and the balance of Cu. A copper alloy with designed components is obtained by combining a diamagnetic material Cu with paramagnetic Nb, and compared with existing medical stainless steel and titanium alloy, the copper alloy has greatly reduced magnetic susceptibility, and specifically, the artifact area and volume are also significantly reduced. In addition, the blank of use of the copper alloy in medical biopsy paracentesis is filled.

Abstract: A conversion device includes a primary side circuit, a secondary side circuit, a transformer, and a control circuit. The primary side circuit includes a primary side switch and is configured to receive an input voltage. The secondary side circuit outputs an output voltage to a load. The transformer comprises a primary winding and a secondary winding, the primary winding is electrically coupled to the primary side circuit and the secondary winding electrically coupled to the secondary side circuit. The control circuit is configured to control a peak value of the current of the primary side switch, to be limited in a band range.

Abstract: A downhole throttling device based on wireless control includes an inlet nozzle, a throttling assembly, an electrical sealing cylinder, a gas guide cylinder, a lower adapter sleeve, an end socket, a female sleeve, and electrical components. The inlet nozzle is connected to the throttling assembly, the throttling assembly is connected to the electrical sealing cylinder and the gas guide cylinder, the electrical sealing cylinder and the gas guide cylinder are both connected to the lower adapter sleeve, the lower adapter sleeve is respectively connected to the end socket and the female sleeve, and the electrical components are arranged in the electrical sealing cylinder. A throttling effect is achieved by detecting the temperature and pressure in a tube by a temperature/pressure sensor in the electrical components and controlling a motor to rotate a movable valve in the throttling assembly by a circuit control assembly, thereby achieving wireless control over downhole throttling.

Abstract: A follow-hold switch circuit comprising: a follower; a sampling sub-circuit for voltage sampling; a bootstrap-control sub-circuit, which provides a bootstrap voltage to the sampling sub-circuit when the circuit is in a following state; a sampling-switch-control sub-circuit, which provides a common-mode voltage to a bootstrap capacitor in the bootstrap-control sub-circuit when the circuit is in a holding state; the follower is connected to an output of the sampling sub-circuit; the sampling sub-circuit is connected to the bootstrap-control sub-circuit and the sampling-switch-control sub-circuit respectively through a sampling switch; the present disclosure can effectively improve the linearity of sampling switches.

Abstract: A fracturing apparatus is provided. The fracturing apparatus includes a plunger pump, a transmission shaft, a main motor, an oil pipe, a first radiator and a noise reduction cabin. The main motor is spaced apart from the plunger pump, the plunger pump is connected with the main motor through the transmission shaft; the oil pipe is configured to be connected with the plunger pump; the first radiator is spaced apart from the plunger pump, the first radiator is configured to dissipate heat from oil in the oil pipe, the main motor, the first radiator and at least part of the oil pipe are all located inside the noise reduction cabin, and the plunger pump is located outside the noise reduction cabin.

Abstract: An interface circuit and an electronic apparatus, including: a programmable current array (1), generating a first current and a second current transmitted to a common mode and differential mode generation circuit (2) according to an input code, and a third current and a fourth current transmitted to a driving bias generation circuit (3) according to the input code; the common mode and differential mode generation circuit (2), generating a common mode voltage according to the first current, and generating a high level voltage and a low level voltage according to the second current and the common mode voltage; a driving bias generation circuit (3), simulating a load according to the third and fourth currents, and generating a bias voltage based on the load and the low and high level voltages; an output driving circuit (4), converting an input signal into a differential signal in which the common mode voltage and a differential mode amplitude are configurable.

Abstract: A processor may automatically generate one or more transcripts based on a media context. The processor may append at least one of the one or more transcripts to the media. The processor may modify the at least one of the one or more transcripts based on an adjustment to a weight factor.

Abstract: A method of generating a cellular model of Alzheimer's disease (AD) comprises integrating AD related gene to hiPSC to induce increased beta secretase and/or Abeta 42 peptides, and the cellular model of Alzheimer's disease (AD) is prepared by the method.

Abstract: A cholesteric liquid crystal display includes a cholesteric liquid crystal device, a color filter element, a first quarter-wave plate, and a light recovery structure. The cholesteric liquid crystal device includes a cholesteric liquid crystal. The color filter element and the first quarter-wave plate overlap the cholesteric liquid crystal device. The first quarter-wave plate and the color filter element are located between the cholesteric liquid crystal and the light recovery structure.

Abstract: The present invention discloses a method for reconstructing incomplete data of X-ray absorption contrast computed tomography (CT) based on deep learning (DL). The method includes the following steps: using a filtered back projection (FBP) algorithm to obtain an initial reconstructed image; forward projecting the initial reconstructed image to obtain artifact-contaminated complete projection sequences; using a DL technique to process the artifact-contaminated projection sequences to obtain artifact-free projection sequences; using the FBP algorithm to reconstruct the artifact-free projection sequences to obtain a final reconstructed image. Compared with the traditional incomplete data reconstruction methods, the examples of the present invention feature a simpler calculation process, fewer parameters to be manually set, a faster calculation speed and higher image quality.

Abstract: A snare trap is provided, including a trigger base and a snare assembly. The snare assembly includes a cable having a noose, an abutting mechanism sleeved on the cable, a restricting mechanism disposed on the cable and an elastic member disposed between the abutting mechanism and the restricting mechanism. The noose is releasably disposed around the trigger base, and the elastic member is compressible and restricted by the restricting mechanism. The elastic member includes a plurality of segments connected with one another, and at least one of the plurality of segments includes a plurality of coils each having an outer diametric dimension different from an outer diametric dimension of another one of the plurality of coils. When the noose is disposed around the trigger base and the elastic member is compressed, at least two of the plurality of coils are radially overlapped with each other.

Abstract: The invention surprisingly found that Lactobacillus plantarum subsp. plantarum PS128 provides an advantageous effect in treatment or prevention of tic disorders and basal ganglia disorders. Accordingly, the invention provides a method of treating or preventing a movement disorder in a subject, comprising administering to a subject an effective amount of cells of a Lactobacillus plantarum subsp. plantarum PS128, which is deposited under DSMZ Accession No. DSM 28632.

Abstract: A cluster transfer robot includes a body, two clamping arms arranged at the bottom of the body, and a first driving mechanism arranged at the bottom of the body. The first driving mechanism includes a driving wheel configured for driving the transfer robot to move. The clamping arm includes a second driving mechanism and a rotating assembly connected to the second driving mechanism, the rotating assembly includes a rotating arm rotatably connected to the body and a supporting wheel arranged on the rotating arm for supporting the transfer robot, the rotating arm is provided with a clamping portion for clamping automobile tire, and two clamping portions of two rotating arms are arranged facing to each other to define a clamping space for the automobile tire when the two clamping portions are close to each other. The cluster transfer robot can greatly reduce the construction cost of intelligent parking lots.

Abstract: The disclosure provides a high-activity long-acting hypoglycemic fusion protein, which is formed by connecting, via a linker peptide or directly, a high-activity Exendin-4 mutant with an optimally mutated Fc fragment of a human immunoglobulin IgG1. The optimally mutated Fc fragment of the human immunoglobulin IgG1 comprises an optimally mutated human IgG1 hinge region and human IgG1 constant regions CH2 and CH3.

Abstract: A method of generating a cellular model of Alzheimer's disease (AD) comprises integrating AD related gene to hiPSC to induce increased beta secretase and/or Abeta 42 peptides, and the cellular model of Alzheimer's disease (AD) is prepared by the method.

Abstract: A method for preparing tulathromycin, and two intermediate compounds shown in formula V and formula VI are provided.

Abstract: The present invention discloses a method for reconstructing incomplete data of X-ray absorption contrast computed tomography (CT) based on deep learning (DL). The method includes the following steps: using a filtered back projection (FBP) algorithm to obtain an initial reconstructed image; forward projecting the initial reconstructed image to obtain artifact-contaminated complete projection sequences; using a DL technique to process the artifact-contaminated projection sequences to obtain artifact-free projection sequences; using the FBP algorithm to reconstruct the artifact-free projection sequences to obtain a final reconstructed image. Compared with the traditional incomplete data reconstruction methods, the examples of the present invention feature a simpler calculation process, fewer parameters to be manually set, a faster calculation speed and higher image quality.