Abstract: Systems and methods for improving substrate fabrication are provided. Subsets of dies of substrates may be inspected at various points in the fabrication process to generate spectra data. The spectra data can be used to generate data that are input to a machine learning model to predict yields for the substrates.

Abstract: A biological sample detection method based on surface-enhanced Raman spectroscopy is disclosed, which relates to the technical field of biological detection. The method includes following operations: washing a substrate used for Raman spectroscopy to obtain a clean substrate; performing surface nanostructuring on the clean substrate to make the clean substrate have a surface Raman enhancement effect, and ultrasonically cleaning the nanostructured substrate with clear water to obtain a surface nanostructured substrate; and inserting the surface nanostructured substrate in a test biological sample, and taking it out after adsorbing the substance to be detected, and then detecting Raman spectrum signals on the surface.

Abstract: Disclosed are a method for manufacturing a high-temperature structural material and a precursor. The method includes following operations: providing a precursor, wherein the precursor is made of a polymer or the polymer and a high-temperature material; processing the precursor into a precursor object with a preset shape; and converting the processed precursor object into a high-temperature material object through a preset processing method.

Abstract: Compositions and methods comprising polynucleotides and polypeptides having EPSP (5-enolpyruvylshikimate-3-phosphate) synthase (EPSPS) activity are provided. In specific embodiments, the sequence has an improved property, such as, but not limited to, improved catalytic capacity in the presence of the inhibitor, glyphosate. Further provided are nucleic acid constructs, plants, plant cells, explants, seeds and grain having the EPSPS sequences. Various methods of employing the EPSPS sequences are provided. Such methods include methods for producing a glyphosate tolerant plant, plant cell, explant or seed and methods of controlling weeds in a field containing a crop employing the plants and/or seeds disclosed herein.

Abstract: Disclosed are a soft bistable magnetic actuator, a fabrication method thereof, a fatigue testing device, and an auto underwater vehicle. The method for fabricating the soft bistable magnetic actuator includes the following operations: casting a soft precursor by injection molding, wherein the soft precursor consists of a soft deformable portion and a soft peripheral portion surrounded, the soft deformable portion is made of magnetic particles and polymer, and the soft peripheral portion is made of a magnetic particle, a mixture of organic liquid, and polymer; and extracting the organic liquid by an organic solvent shrinks the soft peripheral portion, buckles the soft deformable portion towards one side.

Abstract: A method for forming a complex shape three-dimensional ceramic article by printing a first layer of a first material having a first fraction of first ceramic particles and a first fraction of a first polymeric ceramic precursor. A second layer is printed such that it is at least partially disposed on the first layer of a second material having a second fraction of second ceramic particles and a second fraction of a second polymeric ceramic precursor. A composite of the first layer and the second layer is heated at a temperature sufficient to decompose the first and second polymeric ceramic precursors and sinter the article. During the sintering process, the first and second layers with different fractions of ceramic particles undergo different degrees of shrinkage, resulting in a tuneable mismatch of the bilayer structure and accurately achieving a targeted geometry.

Abstract: The present invention provides a method of in situ 4D printing of high-temperature materials including 3D printing a structure of an ink including a precursor. The structure is treated with controlled high energy flow to create a portion which has a different coefficient of thermal expansion/thermal shrinkage ratio. The structure is heated and the difference in the coefficient of thermal expansion creates an interface stress to cause a selected level of deformation. Alternatively, two structures with different coefficients of expansion/thermal shrinkage ratio may be printed. Thermal treatment of the two structures creates an interface stress to cause a selected level of deformation.

Abstract: The present disclosure discloses a new use of desloratadine (DLT) and pharmaceutically acceptable salts thereof in preparing a drug for treating a neurodegenerative disease related to motor dysfunction. The present disclosure shows, through a large number of experimental tests, that desloratadine and the pharmaceutically acceptable salts thereof can improve the state of motor dysfunction in an SOD1-G93A model mouse in the behavioral experimental tests of Rotarod experimental test, gait monitoring experimental test and cage experimental test, and that desloratadine and the pharmaceutically acceptable salts thereof can effectively delay the onset time and prolong the survival cycle of the SOD1-G93A model mouse, and therefore, desloratadine and the pharmaceutically acceptable salts thereof can be used to treat neurodegenerative diseases related to motor dysfunction, including amyotrophic lateral sclerosis.

Abstract: Nonlinear on-chip optical devices using AlScN are described herein. In one aspect, an optical component having nonlinear characteristics can include a first substrate defining a refractive index; and a nonlinear layer, the nonlinear layer disposed on the first substrate, the nonlinear layer comprising an amount of scandium (Sc), and the nonlinear layer defining a refractive index that is higher than the refractive index of the first substrate.

Abstract: Provided are a polymorph of an EP4 receptor antagonist, a preparation method therefor and a use thereof, relating in particular to a polymorph of an EP4 receptor antagonist (S)-4-(1-(2-(4-fluorobenzyl)-4, 7-dihydro-5H-thieno [2,3-c]pyran-3-carboxamido) ethyl) benzoic acid, a preparation method therefor and a use thereof.

Abstract: A method for preparing an entropy-stabilized ceramic thin film coating includes preparing a first layer formed by raw materials with a plurality of metal elements, and subjecting the first layer to reaction with anion thereby transforming at least a portion of the first layer to a second layer. The present invention also discloses an entropy-stabilized ceramic thin film coating and a component coated with an entropy-stabilized ceramic thin film coating.

Abstract: A method for optimizing an ultrasonic imaging system parameter based on deep learning, comprising the following steps: step 1: collecting samples for training neural networks, the samples comprising ultrasound image samples i, and a corresponding ultrasonic imaging system parameter vector sample p used by an ultrasonic imaging system when the ultrasonic image samples are collected; step 2: establishing a neural network model and training the neural networks to convergence by using the samples collected=in step 1, so as to obtain a trained neural network system onn; and step 3: taking the original ultrasonic imaging system parameter vector p or the original ultrasonic image as an input to be input into the neural network system onn trained in step 2, at this moment, a parameter obtained from an output end of onn being an optimized ultrasonic imaging system parameter vector ep=onn(p).

Abstract: Provided in the present invention is a preparation method for a nano organometallic carboxylate which effectively solves the problems of a complex washing process, and cumbersome, dangerous and uneconomical preparation of lye in traditional methods for producing organometallic carboxylates. A new method for preparing high-quality organometallic carboxylates by using a carboxylic acid, caustic soda, a metal oxide or a hydroxide as starting materials, and using ball milling to assist reaction thereof. The present invention not only efficiently utilizes lye, it also obtains high-quality organometallic carboxylates, which overcomes the technical prejudice that the prior art uses calcium chloride, sodium chloride and other salts for poor reaction efficiency. The problem in environmental pollution caused by the washing waste liquid in the existing process is fundamentally solved.

Abstract: Compositions and methods comprising polynucleotides and polypeptides having EPSP (5-enolpyruvylshikimate-3-phosphate) synthase (EPSPS) activity are provided. In specific embodiments, the sequence has an improved property, such as, but not limited to, improved catalytic capacity in the presence of the inhibitor, glyphosate. Further provided are nucleic acid constructs, plants, plant cells, explants, seeds and grain having the EPSPS sequences. Various methods of employing the EPSPS sequences are provided. Such methods include methods for producing a glyphosate tolerant plant, plant cell, explant or seed and methods of controlling weeds in a field containing a crop employing the plants and/or seeds disclosed herein.

Abstract: A method for correcting misalignments is provided. An alignment for each device of a group of devices mounted on a substrate is determined. An alignment error for the group of devices mounted on the substrate is determined based on the respective alignment for each device. One or more correction factors are calculated based on the alignment error. The alignment error is corrected based on the one or more correction factors.

Abstract: A thermoelectric element to convert thermal energy into electrical energy includes a first electrode part, a second electrode part having a different work function than the first electrode part and arranged at a distance from the first electrode part, on a same surface of a substrate as the first electrode part, and a middle part provided between the first electrode part and the second electrode part.

Abstract: A decoupled ETP model processor is configured to store power consumption data retrieved from power systems; convert the power consumption data into power activated time cycles and power non-activated time cycles; derive a thermal resistance (R) parameter and a capacitance (C) parameter for a predetermined heat flow (Q) parameter at each of the outdoor temperatures; compare the converted power activated time cycles to the actual power activated time cycles; compare the converted power non-activated time cycles to the actual power non-activated time cycles; calculate a first improved resistance-capacitance-heat flow (RCQ) parameter set and a respective first outdoor temperature for the compared and converted power activated time cycles to the actual power activated time cycles; calculate the Q parameter at each outdoor temperature during the power activated time cycles; and calculate the R parameter and the C parameter at each outdoor temperature during the power non-activated time cycles.

Abstract: The present disclosure discloses a band-stop filter and a radio frequency device, and the band-stop filter includes a cavity, an input port and an output port disposed on the cavity, and a transmission mainline and a plurality of resonators are disposed within the cavity, both ends of the transmission mainline are connected to the input port or the output port respectively, each resonator includes a resonant chamber and a resonant column disposed within the resonant chamber, a coupling wall is disposed between the resonant column and the corresponding transmission mainline, the coupling wall extends upwardly from the bottom wall of the cavity, the coupling wall and the transmission mainline are coupled.

Abstract: This application provides a driving switching mechanism for a stapling instrument. An actuation driving assembly includes a driving sleeve for driving an end effector to perform a closing action and a knife bar driving rod for driving the end effector to perform a stapling action. A handle driving assembly includes a driving handle and a knife bar driving assembly which includes a knife driving member and a handle driving connecting member. The handle driving connecting member is connected to a handle driving portion. The knife driving member is movably connected to the handle driving connecting member, and is movable relative to the handle driving connecting member to a driving position or a driving disengagement position. When the knife driving member is in the driving position, the knife driving member and the knife bar driving rod are engaged as the handle driving portion moves toward a second position.

Abstract: Provided in the present invention is a preparation method for a nano organometallic carboxylate which effectively solves the problems of a complex washing process, and cumbersome, dangerous and uneconomical preparation of lye in traditional methods for producing organometallic carboxylates. A new method for preparing high-quality organometallic carboxylates by using a carboxylic acid, caustic soda, a metal oxide or a hydroxide as starting materials, and using ball milling to assist reaction thereof. The present invention not only efficiently utilizes lye, it also obtains high-quality organometallic carboxylates, which overcomes the technical prejudice that the prior art uses calcium chloride, sodium chloride and other salts for poor reaction efficiency. The problem in environmental pollution caused by the washing waste liquid in the existing process is fundamentally solved.