Abstract: Disclosed are a pyrazolo[1,5-a]pyridine compound, a preparation method therefor and a use thereof. Also disclosed is a pharmaceutical composition containing the compound as an active ingredient or a pharmaceutically acceptable salt thereof. The present invention further relates to the use of a compound of formula (I) for treating and preventing diseases that can be treated with wild-type, gene fusion-type and mutant (including but not limited to G804 and G810) RET kinase inhibitors, including diseases or conditions mediated by an RET kinase.

Abstract: An anti-shake camera includes a camera body, and a circuit board and a coil fixing plate which are fixed to a back surface of the camera body; a back surface of the coil fixing plate is divided into four areas according to diagonal lines, fan-shaped coils are respectively fixed to two symmetric areas among the four areas, and a rotating shaft is arranged in a center of the diagonal lines; and a substrate is arranged behind the back surface of the coil fixing plate, a surface, opposite to the back surface of the coil fixing plate, of the substrate is provided with a matching mechanism of the rotating shaft, and one or more fan-shaped permanent magnets forming gaps with included angles with the fan-shaped coils are fixed to areas, corresponding to areas of the coil fixing plate where no fan-shaped coils are fixed, on the substrate.

Abstract: Provided are a detection substrate and a ray detector. The detection substrate includes: a base substrate; a plurality of detection pixels located on the base substrate, at least one detection pixel serves as a detection marking pixel. The detection marking pixel includes: a storage capacitor, a first electrode plate of the storage capacitor coupled to a bias voltage end; a discharge circuit configured to write a signal of the bias voltage end into a second electrode plate of the storage capacitor under the control of a first scanning signal end; and a reading circuit coupled to an external reading circuit, the reading circuit configured to write the voltage of the second electrode plate of the storage capacitor into the external reading circuit and write a reference signal of the external reading circuit into the second electrode plate of the storage capacitor under the control of a second scanning signal end.

Abstract: The present invention relates to a pyrazolo[1,5-a]pyridine derivative, a preparation method therefor, and a composition and a use thereof. Specifically, the present invention relates to the compound of formula (I) and the use thereof for the treatment and/or prevention of wild type, gene-fusion type (including but not limited to KIF5B, CCDC6 and NCOA4) and mutant type (including but not limited to V804, G810 and M918) RET kinases-related diseases, including diseases or conditions mediated by RET kinase.

Abstract: The present invention discloses a refrigerator, comprising a compressor compartment disposed in its lower rear portion thereof, wherein the back plate of the compressor compartment has a first air port and a second air port, and the bottom plate is provided with a third air port. The refrigerator further comprises a baffle movably disposed at the first air port to open or close the first air port. The baffle may prevent the hot air discharged from the compressor compartment from blending with cold air and re-entering the compressor compartment after the refrigerator is embedded in the cupboard.

Abstract: A method for implementing a function jump includes receiving a first function, searching, for an address of the first function, a first data structure in which addresses of a plurality of functions are stored, where a patch function used to replace the first function is available when the address of the first function is found, searching a second data structure for an address of the patch function based on the address of the first function, where correspondences between a plurality of functions and patch functions of the functions are stored in the second data structure, jumping from the first function to the patch function of the first function based on the address of the patch function of the first function, and executing the patch function of the first function to respond to the call to the first function.

Abstract: Embodiments of the present disclosure disclose a computing device, and are applied to the field of computing devices. In the present disclosure, a virtual interrupt obtained by a host machine is mapped to a physical interrupt of a physical layer, and a virtual interrupt identifier corresponding to the physical interrupt is transferred to a virtual processor by using the physical layer. When a hardware layer transparently transmits the virtual interrupt identifier to the virtual processor, the virtual processor does not need to exit. This decreases a delay caused by exit of the virtual processor when software implements virtual interrupt routing.

Abstract: A liquid crystal aligning agent includes polymer(s) from at least one of polyamic acid and group of polyimides by ring closure thereof. The acid includes a first segment structure formed by first dianhydride of formula (I) and first diamine of formula (II) or (III). X1 is an amorphous first soft segment. L is single bond, double bond, divalent or trivalent hydrocarbon group having 1 to 3 Cs. Y1 is single bond, O, NH, S, unsaturated double bond(s), or aliphatic, aromatic, heterocyclic or fused ring. One A1 and one A2, combined with Y1, are each C. Remaining A1s and A2s are each CH, CR or N. Z1 is aliphatic, aromatic, heterocyclic or fused ring. A3s and A4s are each CH, CR or N. Neither of numbers of Ns in the A1s, A2s, A3s and A4s is more than two, R1, R2 and R are each hydrogen or aliphatic hydrocarbon group.

Abstract: A drug research and development software repository and a software package management system. The drug research and development software repository includes a user authentication module, a software package upload and index creation module, a baseline release management module, an authorization management module, a software package retrieval and download module, an adapter plug-in, and a storage layer. The software package management system includes an authentication module, a package management service module, a web front-end module, and a command line tool module.

Abstract: The invention belongs to the technical field of the molecular force field and particularly relates to a computing task management and analysis system for molecular force field parameter building and an operation method thereof. The system comprises a computing result analysis module and a computing task management module, the computing result analysis module is connected with the computing task management module, and the computing task management module is connected with a force field building computing server through a cloud computing interface. The operation method comprises: (1) selecting a molecular force field building computing templates; (2) selecting a computing task submitting platform and submitting computing tasks; (3) retrieving computing results; and (4) analyzing the computing results.

Abstract: The present invention relates to the technical field of plant cultivation through artificial light, and particularly provides a light environment method for plant cultivation through full-artificial light to provide a full-artificial light source for plant growth. The light source includes a light wave with a waveband of 620 nm to 760 nm, and the number of photons of the light wave of 620 nm to 760 nm accounts for 64% to 76% of the total number of photons of the light source. Compared with traditional light sources, such as existing fluorescent lamps and high-pressure sodium lamps, the present invention adopting a mode of light source proportion and light source combination can greatly improve the yield of the plant.

Abstract: Disclosed is an optical lens, from an object side to an image side including a first lens, a second lens and a third lens. The camera optical lens satisfies: 1.20?f1/f?1.80; ?2.00?f2/f??1.00; 0.75?f3/f?1.10; ?6.00?R2/R1??2.00; 2.20?R4/R3?8.00; 1.50?d2/d4?3.50; where f, f1, f2 and f3 denote a focal length of the camera optical lens, the first lens, the second lens and the third lens, respectively; R1, R2 denote a central curvature radius of an object-side surface and an image-side surface of the first lens, respectively; R3, R4 denote a central curvature radius of an object-side surface and an image-side surface of the second lens, respectively; d2 denotes an on-axis distance from the image-side surface of the first lens to the object-side surface of the second lens, and d4 denotes an on-axis distance from the image-side surface of the second lens to an object-side surface of the third lens.

Abstract: The present invention provides a general description language data system for directed acyclic graph automatic task flow, including: Step definition layer, Workflow definition layer and Template definition layer; The Step definition layer is the description of a single task, for the input and output declarations of each docker image or other executor, comprises name, type, file and parameters. The Workflow definition layer is a workflow composed of one or more Steps, the dependency topology of these Steps needs to be defined, and shared parameters can also be defined. The Template definition layer is based on a Workflow definition layer. The Template definition layer pre-sets the parameters, and supplies the descriptions, checkers or data source definitions of the parameters. The data center of the present invention is used with the task execution tool, and a programming language needs to be used to implement the corresponding tool.

Abstract: Systems and techniques are described for large field of view imaging. A device's first image sensor captures a first image based on first light from a scene redirected by a light redirection element (e.g., a first prism and/or first reflective surface), and the device's second image sensor captures a second image based on second light from the scene redirected by the light redirection element (e.g., a second prism and/or second reflective surface). The device can modify the first image and/or second image using perspective distortion correction and/or to align one or more properties of two respective depictions of a shared portion of a scene in the two images. The one or more properties can include brightness, contrast, positioning, sharpness, tint, hue, and/or saturation. The device can generate a combined image with a large field of view and smooth transitions by combining the first image and the second image.

Abstract: The present invention provides a method for promoting plant growth, a plant lamp and application thereof. The method at least includes providing an artificial light source for a growing plant. The light source includes a red light with a peak wavelength of 680-695 nm and a light wave half-width lower than 35 nm; or the light source includes a blue light with a peak wavelength of 410-440 nm and a light wave half-width lower than 35 nm. The plant lamp provides the light source for promoting plant growth. By using the light source in the present invention to irradiate the plant, plant growth is significantly promoted.

Abstract: Methods and systems for deploying images to computing systems include predicting an environment for a plurality of processing nodes. Image deployment to the plurality of processing nodes is simulated to determine a subset of the plurality of processing nodes for deployment. One or more images is pre-loaded to the subset of the plurality of processing nodes in advance of a deployment time.

Abstract: Systems and techniques are described for controlling digital imaging field of view. A device's first image sensor captures a first image based on first light redirected by a light redirection element, and the device's second image sensor captures a second image based on second light redirected by the light redirection element. The device can modify the first image and second image using perspective distortion correction, and can generate a combined image with a large field of view by combining the first image and the second image. The light redirection element can include two prisms that have corners cut and polished to form edges, which can be coupled together and/or colored. A refractive index of the adhesive can be selected to minimize light noise in the combined image. A light-absorbent colorant can coat the interface between the edges of the prisms to minimize light noise in the combined image.

Abstract: A control method for a heating device and a heating device are provided. The heating device includes an electromagnetic wave generation module configured to generate an electromagnetic wave signal for heating an object to be processed. The control method includes: determining or obtaining attribute information of the object to be processed, the attribute information at least including food groups, and each of the food groups including at least one food variety; determining operating power and/or operating time of the electromagnetic wave generation module according to the attribute information; and controlling the electromagnetic wave generation module to operate according to the operating power and/or the operating time. Uneven heating and local overheating caused by different contents of substances in foods of different varieties are reduced as compared with using a fixed operating parameter.

Abstract: The present disclosure relates to a counter substrate and display panel. The counter substrate includes a base substrate, PS pattern layer and alignment film. A surface of the PS pattern layer away from the base substrate is a support surface, and the PS pattern layer includes: main PSs in a display area and a peripheral barrier wall in a non-display area. The peripheral barrier wall has an elongated-strip shape and has a same length direction as a corresponding display area side, the support surface of the peripheral barrier wall is closer to the base substrate than that of the main PS, and a distance between the support surfaces of the peripheral barrier wall and main PS in a thickness direction is a first distance. A ratio between a width of the support surface of the peripheral barrier wall and the first distance is less than 100.

Abstract: This disclosure provides a system and method for user interaction in complex web 3D scenes, including a receiving module, a transmission module and a 3D model module. The receiving module receives molecular data. The transmission module analyzes the received molecular data and then enters the two branch modules at the same time. The branch modules include: a view layer unit: processing browser rendering and 3D model construction, the data generated by the branch will finally be presented on the browser page; a data layer unit: processing 3D picking-related business logic, and establishing a list of related model index information for atoms and covalent bonds in molecular data. The 3D model module: establishes a one-to-one correspondence between color and 3D model. This invention simplifies the display model of the molecule for the picking of web 3D molecular visualization and reduces the computational cost of the model data on the rendering.