Patents by Inventor Jian-Sen Li

Jian-Sen Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tagmentation Using Immobilized Transposomes With Linkers
    Publication number: 20230392142
    Abstract: The present disclosure relates to methods, compositions, and kits for treating target nucleic acids, including methods and compositions for fragmenting and tagging nucleic acid (e.g., DNA) using transposome complexes bound to a solid support.
    Type: Application
    Filed: June 1, 2023
    Publication date: December 7, 2023
    Applicants: Illumina, Inc., Illumina Cambridge Limited
    Inventors: Grace Desantis, Stephen M. Gross, Jian-Sen Li, Natalie Morrell, Andrew Slatter, Kevin Shen, Samantha Snow
  • Tagmentation using immobilized transposomes with linkers
    Patent number: 11708573
    Abstract: The present disclosure relates to methods, compositions, and kits for treating target nucleic acids, including methods and compositions for fragmenting and tagging nucleic acid (e.g., DNA) using transposome complexes bound to a solid support.
    Type: Grant
    Filed: January 4, 2021
    Date of Patent: July 25, 2023
    Assignees: Illumina, Inc.
    Inventors: Grace DeSantis, Stephen M. Gross, Jian-Sen Li, Natalie Morrell, Andrew Slatter, Kevin Shen, Samantha Snow
  • FLUORESCENT DETECTION OF AMINES AND HYDRAZINES AND ASSAYING METHODS THEREOF
    Publication number: 20230139797
    Abstract: Provided herein are processes for preparing fluorescent 1-cyano-2-substituted isoindole compounds or N-substituted phthalazinium compounds, comprising reacting an aromatic dialdehyde or aromatic aldehyde-ketone compound with a material that contains primary amino or hydrazine groups, and assaying methods involving the processes thereof.
    Type: Application
    Filed: December 6, 2022
    Publication date: May 4, 2023
    Inventors: Ali Asadi, Jian-Sen Li
  • Fluorescent detection of amines and hydrazines and assaying methods thereof
    Patent number: 11530352
    Abstract: Provided herein are processes for preparing fluorescent 1-cyano-2-substituted isoindole compounds or N-substituted phthalazinium compounds, comprising reacting an aromatic dialdehyde or aromatic aldehyde-ketone compound with a material that contains primary amino or hydrazine groups, and assaying methods involving the processes thereof.
    Type: Grant
    Filed: October 2, 2017
    Date of Patent: December 20, 2022
    Assignee: Illumina, Inc.
    Inventors: Ali Asadi, Jian-Sen Li
  • Compositions and Methods for Improving Library Enrichment
    Publication number: 20210164027
    Abstract: This disclosure describes a hybridization buffer including a crowding agent, a method that includes using the hybridization buffer, and a kit including the hybridization buffer. This disclosure also describes blockers for use in hybrid capture methods, methods of using those blockers, and a kit including those blockers. Additionally, this disclosure describes a method of hybrid capture that does not include amplifying the library members using PCR prior to sequencing the library members.
    Type: Application
    Filed: August 13, 2019
    Publication date: June 3, 2021
    Applicants: Illumina, Inc., Illumina Cambridge Limited
    Inventors: Andrew F. Slatter, Junhua Zhao, Grace DeSantis, Stephen M. Gross, Hayley Marianne Hogan, Jian-Sen Li, Oliver Jon Miller
  • Tagmentation Using Immobilized Transposomes With Linkers
    Publication number: 20210139887
    Abstract: The present disclosure relates to methods, compositions, and kits for treating target nucleic acids, including methods and compositions for fragmenting and tagging nucleic acid (e.g., DNA) using transposome complexes bound to a solid support.
    Type: Application
    Filed: January 4, 2021
    Publication date: May 13, 2021
    Applicants: Illumina, Inc., Illumina Cambridge Limited
    Inventors: Grace DeSantis, Stephen M. Gross, Jian-Sen Li, Natalie Morrell, Andrew Slatter, Kevin Shen, Samantha Snow
  • Tagmentation using immobilized transposomes with linkers
    Patent number: 10920219
    Abstract: The present disclosure relates to methods, compositions, and kits for treating target nucleic acids, including methods and compositions for fragmenting and tagging nucleic acid (e.g., DNA) using transposome complexes bound to a solid support.
    Type: Grant
    Filed: February 20, 2018
    Date of Patent: February 16, 2021
    Assignees: ILLUMINA, INC.
    Inventors: Grace DeSantis, Stephen M. Gross, Jian-Sen Li, Natalie Morrell, Andrew Slatter, Kevin Shen, Samantha Snow
  • FLUORESCENT DETECTION OF AMINES AND HYDRAZINES AND ASSAYING METHODS THEREOF
    Publication number: 20190225880
    Abstract: Provided herein are processes for preparing fluorescent 1-cyano-2-substituted isoindole compounds or N-substituted phthalazinium compounds, comprising reacting an aromatic dialdehyde or aromatic aldehyde-ketone compound with a material that contains primary amino or hydrazine groups, and assaying methods involving the processes thereof.
    Type: Application
    Filed: October 2, 2017
    Publication date: July 25, 2019
    Applicant: ILLUMINA, INC.
    Inventors: Ali Asadi, Jian-Sen Li
  • TAGMENTATION USING IMMOBILIZED TRANSPOSOMES WITH LINKERS
    Publication number: 20180245069
    Abstract: The present disclosure relates to methods, compositions, and kits for treating target nucleic acids, including methods and compositions for fragmenting and tagging nucleic acid (e.g., DNA) using transposome complexes bound to a solid support.
    Type: Application
    Filed: February 20, 2018
    Publication date: August 30, 2018
    Inventors: Grace DeSantis, Stephen M. Gross, Jian-Sen Li, Natalie Morrell, Andrew Slatter, Kevin Shen, Samantha Snow