Abstract: The disclosed technology provides for improving sleep quality of a user by adjusting a sleep environment. A bed system can include, for example, a controller that can retrieve, from a data repository, data for a set of past sleep sessions of a user, identify, based on the data, a past sleep session in the set of past sleep sessions that satisfies sleep quality criteria, determine thermal settings for the bed system based on the data associated with the identified past sleep session of the user, and apply the thermal settings to the bed system for execution during at least one subsequent sleep session of the user.

Abstract: Base calls for a target sequence may be identified relative to a reference sequence by using values from sequencing reads at locations satisfying a high-confidence condition to identify base calls at a given location not satisfying the high-confidence condition. The high-confidence condition may relate to the level of coverage by the sequencing reads at a location of the reference sequence. The quality of measurements of the sequencing reads may be incorporated into the base-call process.

Abstract: Base calls for a target sequence may be identified relative to a reference sequence by using values from sequencing reads at locations satisfying a high-confidence condition to identify base calls at a given location not satisfying the high-confidence condition. The high-confidence condition may relate to the level of coverage by the sequencing reads at a location of the reference sequence. The quality of measurements of the sequencing reads may be incorporated into the base-call process.

Abstract: Base calls for a target sequence may be identified relative to a reference sequence by using values from sequencing reads at locations satisfying a high-confidence condition to identify base calls at a given location not satisfying the high-confidence condition. The high-confidence condition may relate to the level of coverage by the sequencing reads at a location of the reference sequence. The quality of measurements of the sequencing reads may be incorporated into the base-call process.

Abstract: Base calls for a target sequence may be identified relative to a reference sequence by using values from sequencing reads at locations satisfying a high-confidence condition to identify base calls at a given location not satisfying the high-confidence condition. The high-confidence condition may relate to the level of coverage by the sequencing reads at a location of the reference sequence. The quality of measurements of the sequencing reads may be incorporated into the base-call process.

Abstract: One embodiment of the present invention relates to a method of treating data derived from a separation of a nucleic acid sample. The data, which include features indicating the presence of different nucleic acid fragments in the sample are transformed on the basis of spacings between the features to obtain transformed data having a substantially constant spacing between features. Another embodiment of the present invention relates to an electrophoresis separations apparatus having at least one separation volume, a detector, and a processor. The processor is configured to transform the separations data based upon the spacing between features to obtain transformed data having a substantially constant spacing between features.