Patents by Inventor Jianhong Chu

Jianhong Chu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CS1-specific chimeric antigen receptor engineered immune effector cells
    Patent number: 11845794
    Abstract: Disclosed herein are chimeric antigen receptors (CAR) that can specifically recognize tumor-associated antigens (TAA) on multiple myeloma (MM) cells. Also disclosed are immune effector cells, such as T cells or Natural Killer (NK) cells, that are engineered to express these CARs. Therefore, also disclosed are methods of providing an anti-tumor immunity in a subject with MM that involves adoptive transfer of the disclosed immune effector cells engineered to express the disclosed CARs.
    Type: Grant
    Filed: July 9, 2019
    Date of Patent: December 19, 2023
    Assignee: Ohio State Innovation Foundation
    Inventors: Jianhua Yu, Craig Hofmeister, Jianhong Chu
  • CS1-SPECIFIC CHIMERIC ANTIGEN RECEPTOR ENGINEERED IMMUNE EFFECTOR CELLS
    Publication number: 20200002418
    Abstract: Disclosed herein are chimeric antigen receptors (CAR) that can specifically recognize tumor-associated antigens (TAA) on multiple myelorna (MM) cells. Also disclosed are Mullane effector cells, such as T cells or Natural Killer (NK) cells, that are engineered to express these CARs. Therefore, also disclosed are methods of providing an anti-tumor immunity in a subject with MM that involves adoptive transfer of the disclosed immune effector cells engineered to express the disclosed CARs.
    Type: Application
    Filed: July 9, 2019
    Publication date: January 2, 2020
    Inventors: Jianhua Yu, Craig Hofmeister, Jianhong Chu
  • CS1-specific chimeric antigen receptor engineered immune effector cells
    Patent number: 10358494
    Abstract: Disclosed herein are chimeric antigen receptors (CAR) that can specifically recognize tumor-associated antigens (TAA) on multiple myeloma (MM) cells. Also disclosed are immune effector cells, such as T cells or Natural Killer (NK) cells, that are engineered to express these CARs. Therefore, also disclosed are methods of providing an anti-tumor immunity in a subject with MM that involves adoptive transfer of the disclosed immune effector cells engineered to express the disclosed CARs.
    Type: Grant
    Filed: May 2, 2014
    Date of Patent: July 23, 2019
    Assignee: Ohio State Innovation Foundation
    Inventors: Jianhua Yu, Craig Hofmeister, Jianhong Chu
  • CS1-specific chimeric antigen receptor engineered immune effector cells
    Patent number: 10227409
    Abstract: Disclosed herein are chimeric antigen receptors (CAR) that can specifically recognize tumor-associated antigens (TAA) on multiple myeloma (MM) cells. Also disclosed are immune effector cells, such as T cells or Natural Killer (NK) cells, that are engineered to express these CARs. Therefore, also disclosed are methods of providing an anti-tumor immunity in a subject with MM that involves adoptive transfer of the disclosed immune effector cells engineered to express the disclosed CARs.
    Type: Grant
    Filed: May 17, 2017
    Date of Patent: March 12, 2019
    Assignee: Ohio State Innovation Foundation
    Inventors: Jianhua Yu, Craig Hofmeister, Jianhong Chu
  • CS1-SPECIFIC CHIMERIC ANTIGEN RECEPTOR ENGINEERED IMMUNE EFFECTOR CELLS
    Publication number: 20170320941
    Abstract: Disclosed herein are chimeric antigen receptors (CAR) that can specifically recognize tumor-associated antigens (TAA) on multiple myeloma (MM) cells. Also disclosed are immune effector cells, such as T cells or Natural Killer (NK) cells, that are engineered to express these CARs. Therefore, also disclosed are methods of providing an anti-tumor immunity in a subject with MM that involves adoptive transfer of the disclosed immune effector cells engineered to express the disclosed CARs.
    Type: Application
    Filed: May 17, 2017
    Publication date: November 9, 2017
    Inventors: Jianhua Yu, Craig Hofmeister, Jianhong Chu
  • CS1-SPECIFIC CHIMERIC ANTIGEN RECEPTOR ENGINEERED IMMUNE EFFECTOR CELLS
    Publication number: 20160075784
    Abstract: Disclosed herein are chimeric antigen receptors (CAR) that can specifically recognize tumor-associated antigens (TAA) on multiple myeloma (MM) cells. Also disclosed are immune effector cells, such as T cells or Natural Killer (NK) cells, that are engineered to express these CARs. Therefore, also disclosed are methods of providing an anti-tumor immunity in a subject with MM that involves adoptive transfer of the disclosed immune effector cells engineered to express the disclosed CARs.
    Type: Application
    Filed: May 2, 2014
    Publication date: March 17, 2016
    Inventors: Jianhua Yu, Craig Hofmeister, Jianhong Chu