Patents by Inventor Jianhui Zhong

Jianhui Zhong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11925451
    Abstract: The present disclosure discloses a method for synthesizing high-quality magnetic resonance images, wherein the method expands the value ranges of echo time TE and repetition time TR in a magnetic resonance signal formula to negative intervals, and expands the contribution of proton density PD to a negative power. The method can effectively reduce the influence of the measurement error of quantitative magnetic resonance imaging tissue parameters on the tissue contrast of the synthetic magnetic resonance image, and can obviously improve the tissue contrast of the synthetic magnetic resonance image. This method will significantly improve the imaging quality of synthetic magnetic resonance imaging, and promote its detection effect in neuroscience and clinical lesions. This method is expected to improve the imaging quality of synthetic magnetic resonance imaging and promote its detection effect in neuroscience and clinical lesions.
    Type: Grant
    Filed: September 29, 2020
    Date of Patent: March 12, 2024
    Assignee: ZHEJIANG UNIVERSITY
    Inventors: Hongjian He, Jun Li, Xiaozhi Cao, Qiuping Ding, Jianhui Zhong
  • Patent number: 11353531
    Abstract: The present disclosure discloses a method for measuring relaxation time of ultrashort echo time magnetic resonance fingerprinting. In the method, semi-pulse excitation and semi-projection readout are adopted to shorten echo time (TE) to achieve acquisition of an ultrashort T2 time signal; and image acquisition and reconstruction are based on magnetic resonance fingerprint imaging technology. A TE change mode of sinusoidal fluctuation is introduced, so that distinguishing capability of a magnetic resonance fingerprint signal to short T2 and ultrashort T2 tissues is improved, and multi-parameter quantitative imaging of the short T2 and ultrashort T2 tissues and long T2 tissues is realized.
    Type: Grant
    Filed: May 9, 2020
    Date of Patent: June 7, 2022
    Assignee: ZHEJIANG UNIVERSITY
    Inventors: Hongjian He, Qing Li, Huihui Ye, Xiaozhi Cao, Jianhui Zhong, Qiuping Ding
  • Patent number: 11275141
    Abstract: A magnetic resonance diffusion tensor imaging method and corresponding device. The method includes acquiring omnidirectionally sampled diffusion weighted images of a plurality of training samples; performing diffusion tensor model fitting and undersampling for the omnidirectionally sampled diffusion weighted images of each training sample to obtain an omnidirectionally sampled diffusion tensor image and an undersampled diffusion weighted image; training a deep learning network, with the omnidirectionally sampled diffusion tensor images of the plurality of training samples as training targets and the undersampled diffusion weighted images as training data; acquiring undersampled diffusion weighted images of a target object; and inputting the undersampled diffusion weighted images of target objects into the trained deep learning network to obtain the predicted omnidirectionally sampled diffusion tensor images of the target objects. Also, a fiber tracking method and corresponding device.
    Type: Grant
    Filed: September 25, 2019
    Date of Patent: March 15, 2022
    Assignee: Siemens Healthcare GmbH
    Inventors: Jianhui Zhong, Mu Lin, Yi Sun
  • Publication number: 20220057463
    Abstract: The present disclosure discloses a method for measuring relaxation time of ultrashort echo time magnetic resonance fingerprinting. In the method, semi-pulse excitation and semi-projection readout are adopted to shorten echo time (TE) to achieve acquisition of an ultrashort T2 time signal; and image acquisition and reconstruction are based on magnetic resonance fingerprint imaging technology. A TE change mode of sinusoidal fluctuation is introduced, so that distinguishing capability of a magnetic resonance fingerprint signal to short T2 and ultrashort T2 tissues is improved, and multi-parameter quantitative imaging of the short T2 and ultrashort T2 tissues and long T2 tissues is realized.
    Type: Application
    Filed: May 9, 2020
    Publication date: February 24, 2022
    Inventors: Hongjian HE, Qing LI, Huihui YE, Xiaozhi CAO, Jianhui ZHONG, Qiuping DING
  • Publication number: 20210038110
    Abstract: The present disclosure discloses a method for synthesizing high-quality magnetic resonance images, wherein the method expands the value ranges of echo time TE and repetition time TR in a magnetic resonance signal formula to negative intervals, and expands the contribution of proton density PD to a negative power. The method can effectively reduce the influence of the measurement error of quantitative magnetic resonance imaging tissue parameters on the tissue contrast of the synthetic magnetic resonance image, and can obviously improve the tissue contrast of the synthetic magnetic resonance image. This method will significantly improve the imaging quality of synthetic magnetic resonance imaging, and promote its detection effect in neuroscience and clinical lesions. This method is expected to improve the imaging quality of synthetic magnetic resonance imaging and promote its detection effect in neuroscience and clinical lesions.
    Type: Application
    Filed: September 29, 2020
    Publication date: February 11, 2021
    Inventors: Hongjian HE, Jun LI, Xiaozhi CAO, Qiuping DING, Jianhui ZHONG
  • Publication number: 20200096592
    Abstract: A magnetic resonance diffusion tensor imaging method and corresponding device. The method includes acquiring omnidirectionally sampled diffusion weighted images of a plurality of training samples; performing diffusion tensor model fitting and undersampling for the omnidirectionally sampled diffusion weighted images of each training sample to obtain an omnidirectionally sampled diffusion tensor image and an undersampled diffusion weighted image; training a deep learning network, with the omnidirectionally sampled diffusion tensor images of the plurality of training samples as training targets and the undersampled diffusion weighted images as training data; acquiring undersampled diffusion weighted images of a target object; and inputting the undersampled diffusion weighted images of target objects into the trained deep learning network to obtain the predicted omnidirectionally sampled diffusion tensor images of the target objects. Also, a fiber tracking method and corresponding device.
    Type: Application
    Filed: September 25, 2019
    Publication date: March 26, 2020
    Applicant: Siemens Healthineers Ltd.
    Inventors: Jianhui Zhong, Mu Lin, Yi Sun
  • Patent number: 7002348
    Abstract: An RF coil construction for MRI is disclosed. The construction includes a device for cryogenically cooling receiver coils, at least two coil elements being cryogenically cooled by the device and forming an array. Each coil element includes at least two capacitors for tuning and matching the coil element. The construction also includes a circuit connected to each coil element for decoupling the coil element from the transmitter coil(s), and also for decoupling among coil elements.
    Type: Grant
    Filed: September 14, 2004
    Date of Patent: February 21, 2006
    Assignee: University of Rochester
    Inventors: Wingchi Edmund Kwok, Zhigang You, Jianhui Zhong
  • Publication number: 20050030032
    Abstract: An RF coil construction for MRI is disclosed. The construction includes a device for cryogenically cooling receiver coils, at least two coil elements being cryogenically cooled by the device and forming an array. Each coil element includes at least two capacitors for tuning and matching the coil element. The construction also includes a circuit connected to each coil element for decoupling the coil element from the transmitter coil(s), and also for decoupling among coil elements.
    Type: Application
    Filed: September 14, 2004
    Publication date: February 10, 2005
    Inventors: Wingchi Kwok, Zhigang You, Jianhui Zhong
  • Patent number: 6825664
    Abstract: An RF coil construction for MRI is disclosed. The construction includes a device for cryogenically cooling receiver coils, at least two coil elements being cryogenically cooled by the device and forming an array. Each coil element includes at least two capacitors for tuning and matching the coil element. The construction also includes a circuit connected to each coil element for decoupling the coil element from the transmitter coil(s), and also for decoupling among coil elements.
    Type: Grant
    Filed: April 3, 2003
    Date of Patent: November 30, 2004
    Assignee: University of Rochester
    Inventors: Wingchi Edmund Kwok, Zhigang You, Jianhui Zhong
  • Publication number: 20030189426
    Abstract: An RF coil construction for MRI is disclosed. The construction includes a device for cryogenically cooling receiver coils, at least two coil elements being cryogenically cooled by the device and forming an array. Each coil element includes at least two capacitors for tuning and matching the coil element. The construction also includes a circuit connected to each coil element for decoupling the coil element from the transmitter coil(s), and also for decoupling among coil elements.
    Type: Application
    Filed: April 3, 2003
    Publication date: October 9, 2003
    Applicant: UNIVERSITY OF ROCHESTER
    Inventors: Wingchi Edmund Kwok, Zhigang You, Jianhui Zhong
  • Patent number: 6583623
    Abstract: In magnetic resonance imaging, a pulse sequence is used to obtain both water-only and fat-only signals within a single acquisition time. Pulses and readout gradients are applied to take a proton-density-weighted image of the water, a proton-density-weighted image of the fat, and a T2-weighted image of the water. Between the first water readout gradient and the fat readout gradient, a spoiling gradient is applied to spoil the first water echo. Between the fat readout gradient and the second water readout gradient, a refocusing gradient is applied to refocus the second water echo. The proton-density-weighted images of water and fat are combined to form water-plus-fat images free of in-plane and through-plane chemical-shift artifacts.
    Type: Grant
    Filed: March 30, 2001
    Date of Patent: June 24, 2003
    Assignee: University of Rochester
    Inventors: Wingchi Edmund Kwok, Jianhui Zhong, Saara Marjatta Sofia Totterman
  • Patent number: 6528997
    Abstract: In nuclear magnetic resonance imaging of the human brain or the like, multiple quantum coherences, such as intermolecular double quantum coherence (iDQC) between water molecules, are used for soft tissue contrast. A group of pulse sequences are used in which, (a) The standard &bgr;=&pgr;/2 pulse in the original CRAZED sequence is replaced with a &pgr;/3 pulse. The maximum signal derived from iDQCs is increased by a factor of 3{square root over (3)}/4. (b) The position of the acquisition window is adjusted, and a large acquisition window (small bandwidth) is used to sample a broad range of time-domain signals. (c) Receiver dynamic range is optimized. (d) A two-step phase cycle scheme for iDQC-encode gradients is designed to remove additional undesired coherence pathways.
    Type: Grant
    Filed: March 20, 2001
    Date of Patent: March 4, 2003
    Assignee: University of Rochester
    Inventors: Jianhui Zhong, Zhong Chen, Wingchi E. Kwok
  • Patent number: 6373249
    Abstract: A magnetic imaging device, such as an MR scanner, is used to provide a modified three-dimensional gradient echo sequence having a spatial-spectral excitation in which phase-encoding lines are interleaved for the excitation of water and of fat. The phase-encoding lines are spaced by an interval equal to half of the repetition time. The resulting data are sorted for the reconstruction of water-only and fat-only images, which are realigned and combined to form water-fat combined images free of chemical shift artifacts.
    Type: Grant
    Filed: May 19, 2000
    Date of Patent: April 16, 2002
    Assignee: University of Rochester
    Inventors: Wingchi E. Kwok, Jianhui Zhong, Saara Marjatta Sofia Totterman
  • Publication number: 20010050558
    Abstract: In nuclear magnetic resonance imaging of the human brain or the like, multiple quantum coherences, such as intermolecular double quantum coherence (iDQC) between water molecules, are used for soft tissue contrast. A group of pulse sequences are used in which, (a) The standard &bgr;=&pgr;/2 pulse in the original CRAZED sequence is replaced with a &pgr;/3 pulse. The maximum signal derived from iDQCs is increased by a factor of 3{square root}{square root over (3)}/4. (b) The position of the acquisition window is adjusted, and a large acquisition window (small bandwidth) is used to sample a broad range of time-domain signals. (c) Receiver dynamic range is optimized. (d) A two-step phase cycle scheme for iDQC-encode gradients is designed to remove additional undesired coherence pathways.
    Type: Application
    Filed: March 20, 2001
    Publication date: December 13, 2001
    Inventors: Jianhui Zhong, Zhong Chen, Wingchi E. Kwok
  • Patent number: 6288540
    Abstract: A technique for MRI or the like employs optimized orthogonal gradients. For a device having a peak physical magnetic field gradient strength G0, the gradients are optimized if, in physical space, one gradient has a value −0.5G0 while the two gradients orthogonal thereto have the value G0. That is equivalent to an optimized orthogonal gradient space in which one gradient has a value 1.5G0 while the two gradients orthogonal thereto have the value zero. The gradients are cycled over a sequence of six gradient pulses to provide enough data to calculate the diffusion tensor.
    Type: Grant
    Filed: May 19, 2000
    Date of Patent: September 11, 2001
    Assignee: University of Rochester
    Inventors: Zhong Chen, Jianhui Zhong, Wingchi Edmund Kwok