Patents by Inventor Jianliang Xiao
Jianliang Xiao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11974502Abstract: Soft motherboards having rigid plugin modules are described herein. In one aspect of the present disclosure, an electronic device can include a polymeric substrate having: a plurality of slots, each configured for receiving an electronic module; one or more electrical junctions including a stretchable conductive interconnect electronically coupling a slot to another slot of the plurality of slots; and at least one electronic module including: a film configured to: support other components of the electronic module; and be inserted, and be partially housed in, one of the plurality of slots of the polymeric substrate; and at least one electrode coupled to the film and positioned to be in contact with a corresponding electrical junction of the polymeric substrate when the film is partially housed in the polymeric substrate.Type: GrantFiled: February 10, 2022Date of Patent: April 30, 2024Assignee: The Regents of the University of ColoradoInventors: Jianliang Xiao, Yan Sun, Wei Ren
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Publication number: 20240109888Abstract: Compounds having formula (I), and enantiomers, and diastereomers, stereoisomers, pharmaceutically-acceptable salts thereof, are useful as kinase modulators, including RIPK1 modulation. All the variables are as defined herein.Type: ApplicationFiled: July 6, 2023Publication date: April 4, 2024Inventors: Guanglin Luo, Jie Chen, Carolyn Diane Dzierba, David B. Frennesson, Junqing Guo, Amy C. Hart, Xirui Hu, Michael E. Mertzman, Matthew Reiser Patton, Jianliang Shi, Steven H. Spergel, Brian Lee Venables, Yong-Jin Wu, Zili Xiao, Michael G. Yang
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Publication number: 20230413432Abstract: In one aspect, the present disclosure relates to an electronic device comprising: a plurality of electronic chip components; a plurality of liquid metal (LM) electrical interconnects coupled to the plurality of electronic chips; and a polyimine film encapsulating the plurality of electronic chip components and the plurality of LM electrical interconnects. In some embodiments, the polyimine film comprises the product of the polymerization reaction between terephthaldehyde, 3,3diamino-N-methyldipropylamine, and tris(2-aminoethyl)amine.Type: ApplicationFiled: November 4, 2021Publication date: December 21, 2023Inventors: Jianliang Xiao, Wei Zhang, Chuanqian Shi, Zhanan Zou
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Patent number: 11839491Abstract: Systems and methods for a shape-memory in-ear biosensor for polysomnography and monitoring physiological signals are provided. Various embodiments include an earpiece made from a shape memory or temperature-dependent phase transition material embedded into polydimethylsiloxane elastomer body. The earpiece can use electrodes to detect physiological signals by making direct contact with a user's skin and without the use of electrically conductive gel. When heated above the glass transition temperature of the shape memory polymer, various embodiments of the biosensor may be folded. When cooled, the biosensor will maintain the folded shape. The folded biosensor may then be inserted into the ear canal of a user where, in response to heating by the user's body, it partially unfolds to conform to the shape of the ear canal.Type: GrantFiled: October 7, 2020Date of Patent: December 12, 2023Assignee: The Regents of the University of Colorado, a body corporateInventors: Andres Villada, Dana Stamo, Zhanan Zou, Jianliang Xiao
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Patent number: 11759960Abstract: An optical waveguide-type soft photoactuator based on an optical micro/nanofiber includes an optical micro/nanofiber, a first deformed material membrane, and a second deformed material membrane. One end of the optical micro/nanofiber is provided with a taper region and a waist region, and the taper region and the waist region are encapsulated in the first deformed material membrane. The second deformed material membrane covers a side of the first deformed material membrane, and the first deformed material membrane or the second deformed material membrane is doped with a photothermal conversion material. The refractive index of the first deformed material membrane is less than the refractive index of a core of the optical micro/nanofiber. The coefficient of thermal expansion of the first deformed material membrane and a coefficient of thermal expansion of the second deformed material membrane are different.Type: GrantFiled: November 2, 2021Date of Patent: September 19, 2023Assignee: ZHEJIANG LABInventors: Lei Zhang, Jianliang Xiao, Wenzhen Yang, Shuqi Ma, Ni Yao
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Publication number: 20230191623Abstract: An optical waveguide-type soft photoactuator based on an optical micro/nanofiber includes an optical micro/nanofiber, a first deformed material membrane, and a second deformed material membrane. One end of the optical micro/nanofiber is provided with a taper region and a waist region, and the taper region and the waist region are encapsulated in the first deformed material membrane. The second deformed material membrane covers a side of the first deformed material membrane, and the first deformed material membrane or the second deformed material membrane is doped with a photothermal conversion material. The refractive index of the first deformed material membrane is less than the refractive index of a core of the optical micro/nanofiber. The coefficient of thermal expansion of the first deformed material membrane and a coefficient of thermal expansion of the second deformed material membrane are different.Type: ApplicationFiled: November 2, 2021Publication date: June 22, 2023Applicant: ZHEJIANG LABInventors: Lei ZHANG, Jianliang XIAO, Wenzhen YANG, Shuqi MA, Ni YAO
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Patent number: 11590006Abstract: Methods, systems, and methods of manufacture for soft robotic actuators are described herein. In one aspect, a soft robotic actuator can include an elastomeric material defining a cavity; a volume of liquid metal (LM) positioned within the cavity; and an energy source coupled to the LM, where the energy source is adapted or configured to alter a temperature of the volume of LM, whereby altering the temperature of the volume of LM initiates an actuation of the elastomeric material.Type: GrantFiled: November 13, 2020Date of Patent: February 28, 2023Assignee: The Regents of the University of Colorado, a body corporateInventors: Jianliang Xiao, Zhanan Zou
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Patent number: 11518840Abstract: In one aspect, the invention provides a healable, recyclable and malleable e-skin. In certain embodiments, the e-skin comprises sensors that can detect at least one applied stimulus. In other embodiments, the e-skin comprises a dynamic covalent thermo set doped with a nano-particle composition, thereby rendering the doped thermoset conductive. The e-skin of the invention has potential applicability to the fields of robotics, prosthetics, health monitoring, biomedical devices and consumer products.Type: GrantFiled: November 20, 2018Date of Patent: December 6, 2022Assignee: The Regents of the University of ColoradoInventors: Jianliang Xiao, Wei Zhang, Zhanan Zou, Chengpu Zhu
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Publication number: 20220256711Abstract: Soft motherboards having rigid plugin modules are described herein. In one aspect of the present disclosure, an electronic device can include a polymeric substrate having: a plurality of slots, each configured for receiving an electronic module; one or more electrical junctions including a stretchable conductive interconnect electronically coupling a slot to another slot of the plurality of slots; and at least one electronic module including: a film configured to: support other components of the electronic module; and be inserted, and be partially housed in, one of the plurality of slots of the polymeric substrate; and at least one electrode coupled to the film and positioned to be in contact with a corresponding electrical junction of the polymeric substrate when the film is partially housed in the polymeric substrate.Type: ApplicationFiled: February 10, 2022Publication date: August 11, 2022Inventors: Jianliang Xiao, Yan Sun, Wei Ren
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Publication number: 20220221354Abstract: The present disclosure provides a high-performance integrated strain sensing device that is highly stretchable, rehealable, recyclable and reconfigurable. This device can include dynamic covalent thermoset polyimine as the substrate and encapsulation, eutectic liquid metal alloy as the strain sensing unit and interconnects, and off-the-shelf chip components for measuring and magnifying functions. The device can be attached on the knee, elbow, wrist and finger joints for strain sensing and motion monitoring, and can also be attached on the abdomen to accurately measure respiration cycles.Type: ApplicationFiled: January 13, 2022Publication date: July 14, 2022Inventors: Jianliang Xiao, Wei Zhang, Chuanqian Shi
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Publication number: 20210205103Abstract: Methods, systems, and methods of manufacture for soft robotic actuators are described herein. In one aspect, a soft robotic actuator can include an elastomeric material defining a cavity; a volume of liquid metal (LM) positioned within the cavity; and an energy source coupled to the LM, where the energy source is adapted or configured to alter a temperature of the volume of LM, whereby altering the temperature of the volume of LM initiates an actuation of the elastomeric material.Type: ApplicationFiled: November 13, 2020Publication date: July 8, 2021Inventors: Jianliang Xiao, Zhanan Zou
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Publication number: 20210100509Abstract: Systems and methods for a shape-memory in-ear biosensor for polysomnography and monitoring physiological signals are provided. Various embodiments include an earpiece made from a shape memory or temperature-dependent phase transition material embedded into polydimethylsiloxane elastomer body. The earpiece can use electrodes to detect physiological signals by making direct contact with a user's skin and without the use of electrically conductive gel. When heated above the glass transition temperature of the shape memory polymer, various embodiments of the biosensor may be folded. When cooled, the biosensor will maintain the folded shape. The folded biosensor may then be inserted into the ear canal of a user where, in response to heating by the user's body, it partially unfolds to conform to the shape of the ear canal.Type: ApplicationFiled: October 7, 2020Publication date: April 8, 2021Inventors: Andres Villada, Dana Stamo, Zhanan Zou, Jianliang Xiao
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Publication number: 20200291164Abstract: In one aspect, the invention provides a healable, recyclable and malleable e-skin. In certain embodiments, the e-skin comprises sensors that can detect at least one applied stimulus. In other embodiments, the e-skin comprises a dynamic covalent thermo set doped with a nano-particle composition, thereby rendering the doped thermoset conductive. The e-skin of the invention has potential applicability to the fields of robotics, prosthetics, health monitoring, biomedical devices and consumer products.Type: ApplicationFiled: November 20, 2018Publication date: September 17, 2020Inventors: Jianliang Xiao, Wei Zhang, Zhanan Zou, Chengpu Zhu
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Patent number: 9981957Abstract: The present invention relates to a process for preparing substituted piperidine compounds and especially chiral substituted piperidine compounds. The process involves reacting a substituted pyridinium ion with an amine as defined herein, in the presence of a hydrogen donor, a catalysts and a suitable solvent.Type: GrantFiled: March 24, 2015Date of Patent: May 29, 2018Assignee: THE UNIVERSITY OF LIVERPOOLInventors: Jianliang Xiao, Jianjun Wu
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Publication number: 20170107208Abstract: The present invention relates to a process for preparing substituted piperidine compounds and especially chiral substituted piperidine compounds. The process involves reacting a substituted pyridinium ion with an amine as defined herein, in the presence of a hydrogen donor, a catalysts and a suitable solvent.Type: ApplicationFiled: March 24, 2015Publication date: April 20, 2017Inventors: Jianliang XIAO, Jianjun WU
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Patent number: 9340519Abstract: A substituted paracyclophane of formula (I) is provided wherein X1 and X2 are linking groups comprising between 2 to 4 carbon atoms, Y1 and Y2 are selected from the group consisting of hydrogen, halide, oxygen, nitrogen, alkyl, cycloalkyl, aryl or heteroaryl and Z is a substituted or unsubstituted alkyl group, aryl group or heteroaryl group. The substituted paracyclophane provides transition metal catalysts that are useful in C—C and C—N bond formation and asymmetric hydrogenation reactions.Type: GrantFiled: July 21, 2014Date of Patent: May 17, 2016Assignee: Johnson Matthey PLCInventors: Jianliang Xiao, Jiwu Ruan
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Patent number: 9212199Abstract: The present invention relates to an iridium-based catalyst compound for hydrogenating reducible moieties, especially imines and iminiums, the catalyst compounds being defined by the formulas: where ring B is either itself polycyclic, or ring B together with R is polycyclic. The catalysts of the invention are particularly effective in reductive amination procedures 10 which involve the in situ generation of the imine or iminium under reductive hydrogenative conditions.Type: GrantFiled: April 15, 2013Date of Patent: December 15, 2015Assignee: The University of LiverpoolInventors: Dinesh Talwar, Weijun Tang, Chao Wang, Barbara Villa Marcos, Jianliang Xiao
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Publication number: 20150080592Abstract: The present invention relates to an iridium-based catalyst compound for hydrogenating reducible moieties, especially imines and iminiums, the catalyst compounds being defined by the formulas: where ring B is either itself polycyclic, or ring B together with R is polycyclic. The catalysts of the invention are particularly effective in reductive amination procedures 10 which involve the in situ generation of the imine or iminium under reductive hydrogenative conditions.Type: ApplicationFiled: April 15, 2013Publication date: March 19, 2015Inventors: Dinesh Talwar, Weijun Tang, Chao Wang, Barbara Villa Marcos, Jianliang Xiao
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Publication number: 20150073165Abstract: The present invention relates to an iridium-based catalyst compound for hydrogenating reducible moieties, especially imines and iminiums, the catalyst compounds being defined by the formula: (Formula (I)) where ring B is a conjugated ring system with one or more substituents. The catalysts of the invention are particularly effective in reductive amination procedures which involve the in situ generation of the imine or iminium under reductive hydrogenative conditions.Type: ApplicationFiled: April 15, 2013Publication date: March 12, 2015Inventors: Barbara Villa Marcos, Weijun Tang, Dinesh Talwar, Chao Wang, Jianjun Wu, Jianliang Xiao
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Publication number: 20140330012Abstract: A substituted paracyclophane of formula (I) is provided wherein X1 and X2 are linking groups comprising between 2 to 4 carbon atoms, Y1 and Y2 are selected from the group consisting of hydrogen, halide, oxygen, nitrogen, alkyl, cycloalkyl, aryl or heteroaryl and Z is a substituted or unsubstituted alkyl group, aryl group or heteroaryl group. The substituted paracyclophane provides transition metal catalysts that are useful in C—C and C—N bond formation and asymmetric hydrogenation reactions.Type: ApplicationFiled: July 21, 2014Publication date: November 6, 2014Applicant: Johnson Matthey Public Limited CompanyInventors: Jianliang Xiao, Jiwu Ruan