Abstract: The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit Human Respiratory Syncytial Virus (HRSV) or Human Metapneumovirus (HMPV) inhibitors. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HRSV or HMPV infection. The invention also relates to methods of treating an HRSV or HMPV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.

Abstract: The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit Respiratory Syncytial Virus (RSV). The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from RSV infection. The invention also relates to methods of treating an RSV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.

Abstract: The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit Human Respiratory Syncytial Virus (HRSV) or Human Metapneumovirus (HMPV) inhibitors. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HRSV or HMPV infection. The invention also relates to methods of treating an HRSV or HMPV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.

Abstract: The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit Respiratory Syncytial Virus (RSV). The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from RSV infection. The invention also relates to methods of treating an RSV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.

Abstract: Systems and methods to transmit audio-video signals over an optical communication channel are described. One aspect includes receiving a plurality of audio-video electrical signals at an optical transmitter. The optical transmitter may also receive a plurality of out-of-band electrical signals. The optical transmitter may collectively modulate the audio-video electrical signals to generate a composite electrical signal. In one aspect, the optical transmitter bias current-modulates a bias current level of the composite electrical signal using the electrical out-of-band signals, and generates a modulated electrical signal based on the bias current-modulating. The optical transmitter may convert the modulated electrical signal into a modulated optical signal using a laser diode, and transmit the modulated optical signal to an optical receiver over an optical communication channel.

Abstract: Systems and methods for optical transmission of one-or-more out-of-band signals associated with audio-video signal communication are described. In one aspect, an optical receiver receives a first out-of-band electrical signal and a second out-of-band electrical signal from a video sink. The first out-of-band electrical signal may correspond to an audio-video stream previously received or concurrently being received from a video source optical transmitter at the optical receiver. The second out-of-band electrical signal may also correspond to the audio-video stream. The optical receiver may combine the first out-of-band electrical signal and the second out-of-band electrical signal into a transmit electrical signal. In one aspect, the optical receiver converts the transmit electrical signal into an optical signal, and transmits the optical signal to an optical transmitter via an optical communication channel.

Abstract: The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit Human Respiratory Syncytial Virus (HRSV) or Human Metapneumovirus (HMPV) inhibitors. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HRSV or HMPV infection. The invention also relates to methods of treating an HRSV or HMPV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.

Abstract: Systems and methods for signal communication over an optical link are described. One aspect includes receiving a source CONFIG1 signal from a DP master device and a sink CONFIG1 signal from a sink terminal. The source and sink CONFIG1 signals are analyzed. It is determined whether a signal transmission mode is a DP protocol. For a DP protocol, a pair of source AUX signals is received from the DP master device. A pair of sink AUX signals is received from the sink terminal. Communication resource contention between the source and sink AUX signals is identified. A communication direction of the communication resources is transitioned to give the source AUX signals precedence over the sink AUX signals. The source AUX signals are transferred to the sink terminal via the communication resources. The direction of the communication resources is again transitioned. The sink AUX signals are transferred to the DP master device.

Abstract: The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit Human Respiratory Syncytial Virus (HRSV) or Human Metapneumovirus (HMPV) inhibitors. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HRSV or HMPV infection. The invention also relates to methods of treating an HRSV or HMPV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.

Abstract: A rotary positioning adjustment device and a curtain with the same are provided. The rotary positioning adjustment device includes a shaft sleeve (303) and a connecting rod (1). A reel (304) is fixedly connected with an end of the connecting rod (1); a fixed seat (305) is sleeved on the connecting rod (1); the reel (304) is arranged in the fixed seat (305); and a power storage assembly is installed in the shaft sleeve (303). The power storage assembly includes a power input piece (300), a second torsion spring (301) and a power output piece (302); a first support leg (315) of the second torsion spring (301) is connected in a hooked mode with one side of an input block (314) of the power input piece (300), and a second support leg (316) of the second torsion spring (301) is connected in a hooked mode with the other side of the input block (314). The rotary positioning adjustment device further includes a first torsion spring (310).

Abstract: Systems and methods for optical data interconnection are described. One aspect includes a first signal converter that converts first high-speed HDMI electrical signals into high-speed HDMI optical signals, and transmits the optical signals over a first optical communication channel. A second signal converter encodes first low-speed HDMI electrical signals, converts these encoded signals into low-speed HDMI optical signals, and transmits these optical signals over a second optical communication channel. A third signal converter receives the high-speed HDMI optical signals, and converts these optical signals to second high-speed HDMI electrical signals. A fourth signal converter receives the low-speed HDMI optical signals, converts these optical signals to second low-speed HDMI electrical signals, and decodes the second low-speed HDMI electrical signals.

Abstract: Systems and methods for optical data interconnection are described. One aspect includes detecting a first HDMI connection of a first terminal of an optical connector. A second HDMI connection of a second terminal of the optical connector may be detected. One aspect includes determining that the first HDMI connection is associated with an HDMI source, and determining that the second HDMI connection is associated with an HDMI sink. Responsive to determining that the first HDMI connection is associated with the HDMI source, an HDMI transmission mode is selected for the first terminal. Responsive to determining that the second HDMI connection is associated with the HDMI sink, an HDMI reception mode is selected for the second terminal. The first terminal and the second terminal may perform HDMI optical communication via an optical communication channel.

Abstract: The present invention relates to pharmaceutical agents administered to a subject either in combination or in series for the treatment of a Respiratory Syncytial Virus (RSV) infection, wherein treatment comprises administering a compound effective to inhibit the function of the RSV and an additional compound or combinations of compounds having anti-RSV activity.

Abstract: Systems and methods to implement a USB and Thunderbolt optical signal transceiver are described. One method includes detecting presence of a USB sideband signal received over an optical communication channel and associated with a USB communication request. Responsive to the detecting, the method may determine that the USB communication request corresponds to a USB communication mode and perform a sideband negotiation. The USB communication mode may be enabled. A specified number of channels associated with the USB communication request may be determined. USB communication may be performed using the specified number of channels over the optical communication channel in the USB communication mode.

Abstract: Systems and methods to implement a USB and Thunderbolt optical signal transceiver are described. One method includes detecting presence of a USB sideband signal received over an optical communication channel and associated with a USB communication request. Responsive to the detecting, the method may determine that the USB communication request corresponds to a USB communication mode and perform a sideband negotiation. The USB communication mode may be enabled. A specified number of channels associated with the USB communication request may be determined. USB communication may be performed using the specified number of channels over the optical communication channel in the USB communication mode.

Abstract: Systems and methods for signal communication over an optical link are described. One aspect includes receiving a source CONFIG1 signal from a DP master device and a sink CONFIG1 signal from a sink terminal. The source and sink CONFIG1 signals are analyzed. It is determined whether a signal transmission mode is a DP protocol. For a DP protocol, a pair of source AUX signals is received from the DP master device. A pair of sink AUX signals is received from the sink terminal. Communication resource contention between the source and sink AUX signals is identified. A communication direction of the communication resources is transitioned to give the source AUX signals precedence over the sink AUX signals. The source AUX signals are transferred to the sink terminal via the communication resources. The direction of the communication resources is again transitioned. The sink AUX signals are transferred to the DP master device.

Abstract: The present invention discloses Stenotrophomonas maltophilia GYH and its application in degrading chlorinated hydrocarbon pollutants, and the application is carried out as follows: resting cells obtained by spreading cultivation of Stenotrophomonas maltophilia GYH are added to a pH=5-8 inorganic salt medium, and then a chlorinated hydrocarbon pollutant is added, and the cells are cultured at 20-35° C. and 140-180 rpm to degrade the pollutant. The concentration of chlorinated hydrocarbon pollutant which can be removed by Stenotrophomonas maltophilia GYH ranges from 2.9 mg/L to 8.93 mg/L. Therefore, the Stenotrophomonas maltophilia has a highly efficient degradation ability for similar industrial pollutants and is able to withstand high concentrations of these pollutants.

Abstract: Systems and methods for HDMI signal communication over an optical communication link are described. One aspect includes receiving an HDMI control signal from an HDMI master device, and another HDMI control signal from an HDMI sink terminal via a communication resources. The method identifies half-duplex communication resource contention between the HDMI control signal and the other HDMI control signal, and transitions a communication direction of the half-duplex communication resources to give the HDMI control signal precedence over the other HDMI control signal. Subsequent to transitioning the communication direction, the method transfers the HDMI control signal to the HDMI sink terminal via the communication resources. Subsequent to transferring the HDMI control signal, the method again transitions the direction of the half-duplex communication resources, and transfers the other HMDI control signal to the HDMI master device.

Abstract: Methods for USB signal communication over an optical link are described. One aspect includes detecting connection of a device circuit to a USB device. The detecting may further include transmitting an electrical pulse through a reactive network, and detecting a change in a delay associated with the electrical pulse responsive to connecting the device circuit to the USB device. An optical signal associated with the detected connection may be transmitted to a host circuit via an optical communication channel.

Abstract: The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit Respiratory Syncytial Virus (RSV). The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from RSV infection. The invention also relates to methods of treating an RSV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.