Abstract: A composite support system based on a steel-concrete (concrete-filled steel tube) support and a shotcrete arch includes an anchor mesh layer provided on an inner wall of a roadway. A flexible compressible layer is provided on the outer side of the anchor mesh layer; a support frame is erected on the outer side of the flexible compressible layer; reinforcement meshes are respectively arranged on an inner side and an outer side of the support frame; the support frame and the reinforcement meshes form a framework to construct an arch spray layer; the reinforcement meshes and the support frame are embedded into an arch structure to form a rigid layer; the flexible compressible layer is provided between the rigid layer and the anchor spray layer. When the flexible compressible layer is compressed, the flexible compressible layer is deformed toward a reserved deformation space for a yielding purpose.

Abstract: A composite support system based on a steel-concrete (concrete-filled steel tube) support and a shotcrete arch includes an anchor mesh layer provided on an inner wall of a roadway. A flexible compressible layer is provided on the outer side of the anchor mesh layer; a support frame is erected on the outer side of the flexible compressible layer; reinforcement meshes are respectively arranged on an inner side and an outer side of the support frame; the support frame and the reinforcement meshes form a framework to construct an arch spray layer; the reinforcement meshes and the support frame are embedded into an arch structure to form a rigid layer; the flexible compressible layer is provided between the rigid layer and the anchor spray layer. When the flexible compressible layer is compressed, the flexible compressible layer is deformed toward a reserved deformation space for a yielding purpose.

Abstract: The present invention concerns methods of specifically inhibiting an immune response of a subject to one or more selected antigens using an immunosuppressive composition derived from a glioblastoma cell line. The method steps include obtaining a population of antigen presenting cells (APCs); loading the APC population with specific antigens (in auto-immune diseases) or using donor APCs (for transplantation); incubating the APC population with the immunosuppressive composition; and introducing the incubated cells into the subject being treated. The APCs can be monocytes, macrophages, or dendritic cells. This method causes specific inhibition of the immune response because it induces apoptosis and/or anergy in the subject's T cells specific for antigens present on the APCs, but does not affect the immune response to antigens not present on the APC surfaces.