Abstract: The invention provides a radiotherapeutical or radiosurgical system comprising at least two high-intensity radiation sources configured to rotate around a common rotation axis and a ring-shaped imaging device. A three-source configuration is considered as the most cost-effective and will be used as an example for illustration. The configuration of these high-intensity radiation sources and use of a unique compact MLC for each of the radiation sources make it possible for the system to rapidly deliver high-conformal non-coplanar stereotactic radiation treatment in one gantry rotation without any couch rotation. Therefore the invention can deliver high precision and high-conformal non-coplanar stereotactic radiation treatment to any part of the body in an extremely short time (0.1-20 seconds), which may exhibit numerous advantages over the prior art, such as reduction of radiation damage to the circulating immune cells in blood and mitigation of patient motion-induced problems, among others.

Abstract: The present invention provides a radiotherapeutical or radiosurgical system comprising at least two high-intensity radiation sources configured to rotate around a common rotation axis and a ring-shaped imaging device. A three-source configuration is considered as the most cost-effective and will be used as an example for illustration. The three radiation sources are specially configured with each radiation source emits a radiation beam having an angle (?1, ?2 or ?3 respectively) relative to the common rotation axis and targets at a common isocenter. During a radiation treatment, the angles ?1, ?2 and ?3 are independently of each other constant or variable with a magnitude of less than ±15°, and it always remains that ?1??2, ?1??3, and ?2??3.

Abstract: A three-dimensional tumor ruler and holder and methods of use thereof are provided. One embodiment provides a three-dimensional tumor ruler to simultaneously measure the length, width, and height of a tumor when positioned on or near the tumor. The tumor measurements can then be used to calculate tumor volume. Tumor volume can be used to accurately determine for example the dose of a drug or radiation to administer to a subject. In another embodiment, the tumor ruler can be used to position the tumor during administration of a drug or radiation therapy to maximize exposure of the tumor to the therapy.