Patent number: 7230010
Abstract: A 1,2,4-triazole derivative of formula 1 or a non-toxic salt thereof, a preparation method thereof, and a pharmaceutical composition containing the derivative or the salt as an active ingredient are provided: wherein: R1 represents naphthyl, indolyl, benzofuranyl, benzothienyl, benzimidazolyl, benzothiazolyl, benzotriazolyl, benzooxazolyl, quinolinyl, or isoquinolinyl; wherein, R1 is optionally substituted at a substitutable position with one or more radicals independently selected from halogen, hydroxy, nitro, C1-C6 alkyl, C1-C6 haloalkyl, C1-C6 alkoxy, C1-C6 haloalkoxy, cyano, amino, monoalkylamino, and dialkylamino; R2 represents methyl or amino; and A, B, E, and D each independently represent carbon or nitrogen.
Type:
Grant
Filed:
August 1, 2003
Date of Patent:
June 12, 2007
Assignee:
CJ Corp.
Inventors:
Il Hwan Cho, Dong Hyun Ko, Myeong Yun Chae, Taerho Kim, Kyoung Rae Kang, Jong Hoon Kim, Sung Hak Jung, Sang Wook Park, Hyung Ok Chun, Hyung Chul Ryu, Ji Young Noh, Hyun Jung Park, Jie Eun Park, Young Mee Chung
