Abstract: The present disclosure provides a compound function prediction method based on a neural network and a connectivity map (CMAP) algorithm. The compound function prediction method is used to predict an efficacy of a compound, and the compound function prediction method includes the following steps: constructing a compound molecule—encoding vector neural network; constructing and training an encoding vector—marker gene expression variation deep neural network; constructing and training a marker gene expression level or gene expression variation—whole genome gene expression level or gene expression variation neural network; constructing upregulated and downregulated gene sets of a disease or a phenotype; and evaluating a correlation between the compound and the disease or the phenotype.

Abstract: A method for reducing frequency interference, and a communication satellite system. The method includes configuring the communication satellite system, determining a first range of areas in which a spatial isolation angle between the LEO satellite and the GEO satellite does not satisfy a minimum spatial isolation angle within service areas of the movable spot beams, enabling the movable spot beams to not enter the areas, and when the movable spot beams of the transmitting and receiving user antennas of multiple adjacent LEO satellites provide services to a same area, calculating a spatial isolation angles between the movable spot beams of the transmitting and receiving user antennas of any two adjacent LEO satellites, and in response to the spatial isolation angle not satisfying the minimum spatial isolation angle, assigning different sub-frequencies to the movable spot beams that do not satisfy the minimum spatial isolation angle.

Abstract: The present disclosure relates to novel compounds that degrade Bruton's tyrosine kinase (BTK), pharmaceutical compositions containing such compounds, and their use in prevention and treatment of conditions modulated by BTK.

Abstract: The present disclosure relates to novel compounds that inhibit glucose-induced degradation-deficient (GID) E3 ligase, pharmaceutical compositions containing such compounds, and their use in prevention and treatment of cancer and related diseases and conditions.

Abstract: Disclosed are a rotating wheel apparatus, a driving wheel and a robot. The rotating wheel apparatus includes: a rotating assembly, a bearing and a supporting base. The rotating assembly is provided with an accommodating groove. The bearing is accommodated in the accommodating groove and connected to the rotating assembly. The supporting base is close to a notch of the accommodating groove, the supporting base is connected to the bearing, so that the rotating assembly is rotationally connected to the supporting base.

Abstract: A composite solution for enhancing induced disease resistance of lentinan (LNT) to a plant, a preparation method of the composite solution, and a method for enhancing induced disease resistance of LNT to a plant are provided. The composite solution for enhancing induced disease resistance of LNT to a plant includes: an LNT-containing solution and an SPc-containing solution, where SPc is a dendritic macromolecule functionalized by an amino functional group, and has a structural formula shown in formula I, where n=1 to 100. An LNT/SPc complex is produced in the composite solution. SPc spontaneously combines with LNT through hydrogen bonding, such that an agglomerate structure formed by LNT in an aqueous solution is broken and reduced to a nano-scale particle size, and a spherical particle is produced, which can significantly reduce a contact angle of the LNT aqueous solution, and promote the distribution and diffusion of LNT.

Abstract: A method for constructing an efficient product surface defect detection model based on network collaborative pruning is provided. According to an initial product surface defect detection model, the method provides a network-based collaborative pruning method and constructs the efficient product surface defect detection model. On a premise of ensuring an accuracy of a product defect detection method, a product surface defect detection time is reduced to satisfy manufacturer's requirements on the product surface defect detection time and accuracy of product surface defects.

Abstract: A touch substrate manufacturing method, for manufacturing a target touch substrate to be assembled with a display substrate, is provided. A size of an active display region of the display substrate is a first preset size. The method includes: providing a touch substrate to be processed having a second preset size, the second preset size being greater than the first preset size; and cutting, in at least one cutting direction, the touch substrate to be processed to obtain the target touch substrate, the cutting direction being parallel to an extending direction of a touch channel on the touch substrate to be processed. A manufacturing method for touch module, a touch substrate and a touch module are also provided.

Abstract: A display panel includes a display region and a photoelectric sensing region which includes a light transmitting region and a frame region surrounding the light transmitting region; the frame region includes a first region surrounding the light transmitting region, a second region on a side of the first region away from the light transmitting region and surrounding the first region, and a third region between the second region and the display region. The spacers are in an array and in the display region but not in the light transmitting region. A plurality of first support pillars are in the first region, arranged around the light transmitting region, and spaced from each other. A plurality of second support pillars are in the second region, around the second region, and spaced from each other. A plurality of third support pillars are in the third region in an array.

Abstract: Disclosed by the present invention are an aqueous polyurethane functional mask substrate and an application thereof. Two kinds of water-based polyurethane dispersions are used as the main components of the mask substrate. The transdermal penetration and absorption of functional ingredients such as whitening, moisturizing and anti-aging ingredients in facial mask products are promoted by means of the special cross-linked structures of polyurethane films. During use, a mask is evenly applied to the face; and after the mask dries, the entire mask may be removed directly or removed after being moistened using water. The mask substrate according to the present invention is also applicable to body masks such as a hand mask, a neck mask and a back mask.

Abstract: A microspheric ionomer having a cross-linked structure, a preparation method therefor, applications thereof, and a preparation system thereof. The ionomer comprises structure units A represented by formula (1), structure units B represented by formula (2), and a cross-linking structure provided by a cross-linking agent, M being separately selected from H, a metal cation, and a straight chain, a saturated alkyl of branched or ring-shaped C1-C20, R being H or a methyl; and metal cations are introduced to part of structure units A in the ionomer. The ionomer shows an outstanding effect on nucleation of PET, serves as a nucleating agent for PET modification, so as to obtain a corresponding PET composition.

Abstract: The invention provides a method for cargo sorting, configured to control an end effector with a package placement platform to sort the cargo, and the method includes: moving the package placement platform to a package obtaining position and obtaining the cargo to be sorted that enters into the package placement platform; moving the package placement platform to a package storage location; and exerting a first force to push the cargo into a package storage unit. With the help of the package placement platform, the method of the invention can receive the packages of different types or different sizes or different material so as to sort and transport all kinds of packages.

Abstract: Disclosed is a recoverable and self-expanding short-frame valve suitable for aortic valve regurgitation, including a tubular frame and valve leaflets. The tubular frame can contract to a delivery configuration or expand to a use configuration in a radial direction; the tubular frame includes a first portion and a second portion integrally formed and coaxially arranged; a waist portion is formed at the junction of the first portion and the second portion when the tubular frame is in the use configuration; and the second portion is divergently arranged in a direction away from the waist portion. According to the present disclosure, the complete recovery of the valve can be realized without affecting the later coronary intervention.

Abstract: The present disclosure provides a method for preparing lithium iron phosphate from ferric hydroxyphosphate, including: purifying ferrous sulfate to form a ferrous sulfate solution, adding hydrogen peroxide, phosphoric acid, an ammonium dihydrogen phosphate solution and ammonia water into the ferrous sulfate solution and then reacting to form a mixed slurry, holding the mixed slurry at a temperature for a period of time, and then washing with water and subjecting to press filtration to form ferric hydroxyphosphate precursors with different iron-phosphorus ratios; then flash drying, sintering at a high temperature, and pulverizing to obtain ferric hydroxyphosphate precursors with different iron-phosphorus ratios and different specific surface areas.

Abstract: A fusion method of satellite-based and ground-based lightning data includes S1, selecting valid data in the satellite-based and ground-based lightning data; S2, determining a time threshold for fusing the satellite-based and ground-based lightning data; S3, determining a spatial threshold for fusing the satellite-based lightning data and the ground-based lightning data; and S4, constructing a data fusion scheme to obtain a fused all lightning data set.

Abstract: Provided is an organic light-emitting diode display substrate, including: a source/drain layer, a planarization layer and an anode layer which are laminated in sequence, wherein the source/drain layer includes at least one pair of first signal lines; the anode layer includes a common power line, wherein the common power line is provided with vent holes; overlapping areas between two first signal lines in each pair of the first signal lines and a projection pattern of the vent hole are equal, the overlapping area being greater than 0, wherein the projection pattern of the vent hole is a pattern of an orthographic projection of the vent hole in the common power line on the source/drain layer. A display panel and a display device are also provided.

Abstract: The present disclosure provides a speaker diaphragm and a speaker. The diaphragm includes a thermoplastic polyester elastomer film layer, a thermoplastic polyester elastomer being a copolymer composed of a hard segment A of polyester and a soft segment B of polyether or aliphatic polyester, wherein the thermoplastic polyester elastomer film layer has Young's modulus of 1-1000 MPa, with an elastic recovery rate after 10% strain being greater than or equal to 80%. The speaker diaphragm has a good stiffness, a good damping performance and a good resilience.

Abstract: Provided are a display apparatus and a process method for the display apparatus. The display apparatus includes a display; a communicator, communicating with the network; a remote controller; a memory; and a processor configured for executing instructions in the memory to cause the display apparatus to perform: obtaining video source information from a target video source currently played by the display, where the video source information includes signal source information and type information; determining picture modes corresponding to the target video source according to the signal source information and the type information; displaying the picture modes corresponding to the target video source in a picture mode list; in response to a selection instruction for selecting a target picture mode, obtaining image adjustment parameters corresponding to the target picture mode; and adjusting image quality of the target video source according to the image adjustment parameters.

Abstract: Embodiments of the present invention relate to the field of communications methods and technologies, and in particular, to a transmission method and apparatus. The transmission method includes: generating, by a first device, a sequence based on one or more transmission parameters, where the one or more transmission parameters include at least one of the following: a time domain resource type, transmission waveform indication information, subcarrier spacing indication information, device type information, service type indication information, multiple-input multiple-output MIMO parameter information, duplex mode indication information, control channel format indication information, and transmission carrier indication information; generating to-be-transmitted information by using the sequence; and sending the to-be-transmitted information. According to the transmission method and apparatus in the embodiments of the present invention, a new transmission error check mechanism is provided.