Patents by Inventor Jihua CHEN
Jihua CHEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240186820Abstract: The present invention discloses a power source transfer circuit for switching among a plurality of power sources to supply power to a load. The power source transfer circuit includes a first switch, a second switch and a bypass switch, wherein one of the plurality of power sources supplies power to the load via the first switch and the second switch, and wherein the bypass switch is connected in parallel to the second switch on a neutral line and is configured to control neutral overlapping duration during switching among the plurality of power sources. The power source transfer circuit including a bypass switch provided by the present disclosure can reduce the neutral overlapping duration to microseconds during power source transfer, so as to realize fast and reliable response.Type: ApplicationFiled: June 28, 2023Publication date: June 6, 2024Applicant: Schneider Electric Industries SASInventors: Xiaohang Chen, Haijun Zhao, Ying Shi, Jiamin Chen, Yangfeng Song, Qing Yang, Jihua Dong
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Publication number: 20240173102Abstract: Dental attachment positioning apparatuses and methods of use. A dental attachment apparatus may include an orthodontic attachment having a surface shaped to conform to a contour of a buccal surface of a tooth, and one or more registration surfaces that are shaped to conform to one or more occlusal surfaces of the patient's teeth. The one or more registration surfaces may be configured to aid in proper positioning or orientation of the orthodontic attachment. When the attachment positioning apparatus is placed on the patient's dentition, the orthodontic attachment is positioned at a specified location with respect to the buccal surface of the tooth.Type: ApplicationFiled: February 7, 2024Publication date: May 30, 2024Inventors: Peter WEBBER, Yan CHEN, Jihua CHENG, Bastien PESENTI, Chunhua LI, Jennifer C. CHEN
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Patent number: 11980681Abstract: The invention relates to a dentin collagen fibril demineralizing material, and a preparation method and application thereof. The invention relates to a conjugate of water-soluble chitosan and an aminocarboxylic acid metal chelating agent used for dental demineralization, preferably dentin demineralization. The invention also discloses a dentin collagen fibril demineralizing material and a preparation method and application thereof, wherein the material is prepared from 0.5-1 part by mass of water-soluble chitosan, 10-30 parts by mass of EDTA, and 0.8-1.5 parts by mass of cross-linking agent. The invention relates to a dental demineralization composition comprising a conjugate and a material of the invention. The conjugate, material and composition can be used for dentin demineralization treatment before dental bonding and restoration.Type: GrantFiled: May 13, 2022Date of Patent: May 14, 2024Assignee: The Fourth Military Medical University of Chinese People's Liberation ArmyInventors: Lina Niu, Jihua Chen, Zhiming Zheng, Jingmei Guo, Fan Yu, Kai Jiao
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Patent number: 11971180Abstract: An outdoor unit of an air conditioner includes an outdoor-unit main control circuit, a power supply, a power supply control circuit, and an outdoor-unit communication circuit. The power supply control circuit is disposed in a loop of a power supply line for supplying power to the power supply, and is configured to control the power supply line to supply power to the power supply by controlling on/off of the loop; and the power supply is configured to supply power to the outdoor-unit main control circuit and the outdoor-unit communication circuit after receiving the power supplied from the power supply line.Type: GrantFiled: June 30, 2021Date of Patent: April 30, 2024Assignee: HISENSE (GUANGDONG) AIR CONDITIONER CO., LTD.Inventors: Jianneng Zhang, Yongping Cao, Xidong Li, Minan Wu, Xiaoqin Wei, Jihua Chen
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Patent number: 11931222Abstract: The present disclosure provides methods, computing device readable medium, devices, and systems having a dental attachment formation structures. One dental appliance includes a body having a first surface shaped to abut an exterior surface of a tooth and a well portion of the first surface shaped to form an attachment that is to be attached to the exterior surface of the tooth, a release layer formed over a surface of the well to allow the attachment to be removed from the well, and an attachment material that is used to form the attachment positioned within the well.Type: GrantFiled: November 12, 2015Date of Patent: March 19, 2024Assignee: Align Technology, Inc.Inventors: Peter Webber, Yan Chen, Jihua Cheng, Bastien Pesenti, Chunhua Li, Jennifer C. Chen
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Publication number: 20240027432Abstract: The inventions provide immunoassays for reducing the effects of interference in the detection and quantification of analytes, including but not limited to cytokines, enzymes, antibodies, and others by acidifying samples and allowing for binding of the analytes and corresponding capture reagents in the acidified samples without neutralization.Type: ApplicationFiled: July 12, 2023Publication date: January 25, 2024Inventors: Joshua Zylstra, Giane Oliveira Sumner, Michael A. Partridge, Jihua Chen
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Patent number: 11845234Abstract: A vacuum bag system (VBS) for forming pre-consolidated composite blanks has a blank enclosure for sealing around a periphery of the blank, while leaving a second side of the blank exposed, an articulated forming caul (AFC) with at least two facets, each facet effectively jointedly coupled to an adjacent facet, and having a respective, independently controlled, heater integrated with, or coupled to the facet. The VBS further has a forming enclosure for sealing around a periphery of a tool. The blank enclosure brings the blank and the facets into uniform thermal contact resistance and mechanical contact; and permits the articulated AFC to distribute thermal and mechanical load across the blank during forming, even as the facets move to align to faces of the mold.Type: GrantFiled: January 24, 2020Date of Patent: December 19, 2023Assignee: National Research Council of CanadaInventors: Ali Yousefpour, Drazen Djokic, Simon Hind, Meysam Rahmat, Steven Roy, Marc-Andre Octeau, Jihua Chen
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Publication number: 20230372585Abstract: Disclosed are nucleic acid-calcium phosphate nanoparticle complexes and application thereof in biomineralization. Specifically, disclosed are a biological mineralizer and a preparation method thereof. The mineralizer contains a complex formed by nucleic acid and amorphous calcium phosphate nanoparticles. Further, disclosed is a collagen fiber product containing the biological mineralizer or treated with the biological mineralizer, such as a medical device for being implanted into a patient. Further, disclosed is use of the biological mineralizer or the collagen fiber product in treatment of bone-associated diseases or disorders or improvement of bone conditions of patients. Further, disclosed is a method of using the biological mineralizer to induce biomimetic mineralization of collagen fibers or a preparation method of a mineralized collagen fiber product.Type: ApplicationFiled: August 7, 2020Publication date: November 23, 2023Inventors: Lina NIU, Jihua CHEN, Kia JIAO, Minjuan SHEN, Yuxuan MA, Jianfei YAN, Qianqian WAN, Jing LI
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Publication number: 20230266333Abstract: The present disclosure is directed towards modifying binding molecules in order to minimize pre-existing binding interactions, including binding molecules engineered to minimize or mitigate background reactivity in a sample matrix caused by drug non-specific binding interactions.Type: ApplicationFiled: September 19, 2022Publication date: August 24, 2023Inventors: Giane Oliveira SUMNER, Jihua CHEN, Michael PARTRIDGE, Albert TORRI, Manoj RAJADHYAKSHA
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Publication number: 20230110651Abstract: The present invention generally pertains to methods of determining concentrations of drugs and their targets. In particular, the present invention, in part, pertains to use of a mild acidic assay condition to determine total drug and total target concentrations to mitigate either target interference or drug interference. The present invention also discloses a free target assay using a capture agent that has a lower affinity with a much slower association and dissociation rate compared to the drug.Type: ApplicationFiled: September 28, 2022Publication date: April 13, 2023Inventors: Jihua Chen, Kimberly Kendra, Stacey Shank, Lisa DeStefano, Matthew Andisik, Michael Partridge, Albert Torri, Giane Oliveira Sumner
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Patent number: 11448651Abstract: The present disclosure is directed towards modifying binding molecules in order to minimize pre-existing binding interactions, including binding molecules engineered to minimize or mitigate background reactivity in a sample matrix caused by drug non-specific binding interactions.Type: GrantFiled: July 10, 2019Date of Patent: September 20, 2022Assignee: Regeneron Pharmaceuticals, Inc.Inventors: Giane Oliveira Sumner, Jihua Chen, Michael Partridge, Albert Torri, Manoj Rajadhyaksha
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Publication number: 20220273546Abstract: The invention relates to a dentin collagen fibril demineralizing material, and a preparation method and application thereof. The invention relates to a conjugate of water-soluble chitosan and an aminocarboxylic acid metal chelating agent used for dental demineralization, preferably dentin demineralization. The invention also discloses a dentin collagen fibril demineralizing material and a preparation method and application thereof, wherein the material is prepared from 0.5-1 part by mass of water-soluble chitosan, 10-30 parts by mass of EDTA, and 0.8-1.5 parts by mass of cross-linking agent. The invention relates to a dental demineralization composition comprising a conjugate and a material of the invention. The conjugate, material and composition can be used for dentin demineralization treatment before dental bonding and restoration.Type: ApplicationFiled: May 13, 2022Publication date: September 1, 2022Inventors: Lina NIU, Jihua CHEN, Zhiming ZHENG, Jingmei GUO, Fan YU, Kai JIAO
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Publication number: 20220072816Abstract: A vacuum bag system (VBS) for forming pre-consolidated composite blanks has a blank enclosure for sealing around a periphery of the blank, while leaving a second side of the blank exposed, an articulated forming caul (AFC) with at least two facets, each facet effectively jointedly coupled to an adjacent facet, and having a respective, independently controlled, heater integrated with, or coupled to the facet. The VBS further has a forming enclosure for sealing around a periphery of a tool. The blank enclosure brings the blank and the facets into uniform thermal contact resistance and mechanical contact; and permits the articulated AFC to distribute thermal and mechanical load across the blank during forming, even as the facets move to align to faces of the mold.Type: ApplicationFiled: January 24, 2020Publication date: March 10, 2022Applicant: National Research Council of CanadaInventors: Ali YOUSEFPOUR, Drazen DJOKIC, Simon HIND, Meysam RAHMAT, Steven ROY, Marc-Andre OCTEAU, Jihua CHEN
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Publication number: 20210325055Abstract: An outdoor unit of an air conditioner includes an outdoor-unit main control circuit, a power supply, a power supply control circuit, and an outdoor-unit communication circuit. The power supply control circuit is disposed in a loop of a power supply line for supplying power to the power supply, and is configured to control the power supply line to supply power to the power supply by controlling on/off of the loop; and the power supply is configured to supply power to the outdoor-unit main control circuit and the outdoor-unit communication circuit after receiving the power supplied from the power supply line.Type: ApplicationFiled: June 30, 2021Publication date: October 21, 2021Applicant: Hisense (Guangdong) Air Conditioner Co., Ltd.Inventors: Jianneng ZHANG, Yongping CAO, Xidong LI, Minan WU, Xiaoqin WEI, Jihua CHEN
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Publication number: 20210293811Abstract: The present invention provides methods and systems to detect, quantify or characterize anti-drug antibodies which are induced by the administration of pharmaceutical products. The methods and systems include the use of a binding partner of a target and/or a co-factor to improve the detection of anti-drug antibodies in serum samples in the presence of soluble targets based on competitive target binding. The methods and systems also include the use of immuno-depletion to improve the detection.Type: ApplicationFiled: March 16, 2021Publication date: September 23, 2021Inventors: Jihua Chen, Kimberly Kendra, Albert Torri, Giane Oliveira Sumner
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Publication number: 20200330360Abstract: a The invention relates to a dentin collagen fibril demineralizing material, and a preparation method and application thereof. The invention relates to a conjugate of water-soluble chitosan and an aminocarboxylic acid metal chelating agent used for dental demineralization, preferably dentin demineralization. The invention also discloses a dentin collagen fibril demineralizing material and a preparation method and application thereof, wherein the material is prepared from 0.5-1 part by mass of water-soluble chitosan, 10-30 parts by mass of EDTA, and 0.8-1.5 parts by mass of cross-linking agent. The invention relates to a dental demineralization composition comprising a conjugate and a material of the invention. The conjugate, material and composition can be used for dentin demineralization treatment before dental bonding and restoration.Type: ApplicationFiled: February 14, 2020Publication date: October 22, 2020Inventors: Lina NIU, Jihua CHEN, Zhiming ZHENG, Jingmei GUO, Fan YU, Kai JIAO
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Publication number: 20200018754Abstract: The present disclosure is directed towards modifying binding molecules in order to minimize pre-existing binding interactions, including binding molecules engineered to minimize or mitigate background reactivity in a sample matrix caused by drug non-specific binding interactions.Type: ApplicationFiled: July 10, 2019Publication date: January 16, 2020Inventors: Giane SUMNER, Jihua CHEN, Michael PARTRIDGE, Albert TORRI, Manoj RAJADHYAKSHA
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Publication number: 20200018770Abstract: The present disclosure provides methods for mitigating drug target interference in an anti-drug antibody (ADA) immunoassay, wherein the ADA immunoassay comprises one or more target blocking reagents under mild basic pH assay conditions.Type: ApplicationFiled: July 9, 2019Publication date: January 16, 2020Applicants: Regeneron Pharmaceuticals, Inc., Regeneron Pharmaceuticals, Inc.Inventors: Giane Sumner, Jihua Chen