Patents by Inventor Jill Murrell

Jill Murrell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Transgenic mouse expressing APP770-V717F
    Patent number: 6184435
    Abstract: Methods for screening for risk of Alzheimer's disease involve assaying for a guanine to thymine substitution at position 1924 of the gene encoding the human amyloid precursor protein. Also described are transgenic non-human mammals, especially transgenic mice, harboring an expressable gene sequence encoding human amyloid precursor protein having a phenyalanine for valine amino acid substitution in the transmembrane domain of the amyloid precursor protein.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: February 6, 2001
    Assignee: Advanced Research and Technology Institute
    Inventors: Merrill D. Benson, Jill Murrell, Martin Farlow, Bernardino Ghetti
  • Method for screening for alzheimer's disease
    Patent number: 5879883
    Abstract: Method for screening for risk of Alzheimer's disease involve assaying for a guanine to thymine substitution at position 1924 of the gene encoding the human amyloid precursor protein. Also described are transgenic mammals harboring an expressable gene sequence encoding human amyloid precursor protein having a phenyanine for valine amino acid substitution in the transmembrane domain of the amyloid precursor protein.
    Type: Grant
    Filed: May 3, 1995
    Date of Patent: March 9, 1999
    Assignee: Indiana University Foundation
    Inventors: Merrill D. Benson, Jill Murrell, Martin Farlow, Bernardino Ghetti