Abstract: A method of manufacturing multi-color hosiery comprises at least the steps of: a. providing a pattern knitter which has a main control computer to process color differentiation and set up yarn feeding commands according to a knitting color layout of hosiery; b. selecting total number of colored yarns and color types of pattern color yarns, and mounting the colored yarns on yarn racks, and arranging all knitting sets of a feeder support of the pattern knitter to match the colored yarns up to forty six different color types; and c. controlling yarn fingers through the main control computer according to sequence of the yarn feeding commands to perform knitting operation to finish a hosiery body. Any pattern color on the hosiery can be knitted to one row of the hosiery body.