Abstract: The invention relates to activated Streptococcus pneumoniae serotype 10A, 22F or 33F polysaccharides and processes for their preparation. The invention also relates to immunogenic conjugates comprising Streptococcus pneumoniae serotype 10A, 22F or 33F polysaccharides covalently linked to a carrier protein, processes for their preparation and immunogenic compositions and vaccines comprising them.

Abstract: A touch panel includes: a substrate having a first region and a second region. A plurality of sensing cells are disposed in the first region and a pad portion is disposed in the second region. An insulating interlayer is disposed on the plurality of sensing cells, a connection pattern is disposed on the insulating interlayer, with the connection pattern being electrically connected to adjacent sensing cells through contact holes. A transparent conductive pattern is disposed in the second region and on the insulating interlayer, with the transparent conductive pattern being electrically connected to the plurality of sensing cells and the pad portion.

Abstract: The invention relates to activated Streptococcus pneumoniae serotype 10A, 22F or 33F polysaccharides and processes for their preparation. The invention also relates to immunogenic conjugates comprising Streptococcus pneumoniae serotype 10A, 22F or 33F polysaccharides covalently linked to a carrier protein, processes for their preparation and immunogenic compositions and vaccines comprising them.

Abstract: The present disclosure relates generally to methods of preparing glycoconjugates containing a saccharide conjugated to a carrier protein by use of stable nitroxyl radical related agent/oxidant as an oxidizing agent, to immunogenic compositions comprising such glycoconjugates, and to methods for the use of such glycoconjugates and immunogenic compositions.

Abstract: The present invention relates to new immunogenic compositions comprising conjughated Streptococcus pneumoniae capsular saccharide antigens (glycoconjugates) and uses thereof. Immunogenic compositions of the present invention will typically comprise at least one glycoconjugate from a S. pneumoniae serotype not found in PREVNAR®, SYNFLORIX® and/or PREVNAR 13®. The invention also relates to vaccination of human subjects, in particular infants and elderly, against pneumococcal infections using said novel immunogenic compositions.

Abstract: In a display device foldable along a folding axis, the display device includes: a display panel configured to display an image at a display region; and a touch unit configured to sense a touch input at the display region, and sense a folding state of the display device, wherein the touch unit includes: a plurality of first sensors arranged in a matrix on a same plane; and a second sensor overlapping the folding axis, the second sensor comprising a conductive line of which at least a portion is bent.

Abstract: A composite electronic component composed of a composite body including a capacitor and an electrostatic discharge (ESD) protection device coupled to each other. The capacitor includes a ceramic body in which a plurality of dielectric layers and internal electrodes are stacked with a respective dielectric layer therebetween. The ESD protection device includes first and second electrodes disposed on the ceramic body, a discharging part disposed between the first and second electrodes, and a protective layer disposed on the first and second electrodes and the discharging part. An input terminal disposed on a first end surface of the composite body and is connected to internal electrodes and the first and second electrodes. A ground terminal formed on a second end surface of the composite body and is connected to internal electrodes and the first and second electrodes.

Abstract: The present disclosure relates generally to methods of preparing glycoconjugates containing a saccharide conjugated to a carrier protein by use of stable nitroxyl radical related agent/oxidant as an oxidizing agent, to immunogenic compositions comprising such glycoconjugates, and to methods for the use of such glycoconjugates and immunogenic compositions.

Abstract: The invention provides eTEC linked glycoconjugates comprising a saccharide covalently conjugated to a carrier protein through a (2-((2-oxoethyl)thio)ethyl)carbamate (eTEC) spacer, immunogenic compositions comprising such glycoconjugates, and methods for the preparation and use of such glycoconjugates and immunogenic compositions.

Abstract: The present invention relates generally to glycoconjugates comprising a saccharide covalently conjugated to a carrier protein through a spacer containing ((2-oxoethyl)thio)). In an aspect the invention provides oxo-eT linked glycoconjugates comprising a saccharide covalently conjugated to a carrier protein through a ((2-oxoethyl)thio) spacer having the formula (I): wherein: A is a group (C?X)m wherein X is S or O and m is 0 or 1; B is a bond, O, or CH2; and when m is 0, B can also be (C?O); R is a C2-C16 alkylene, C2-C16 heteroakylene, NH—C(?O)—C2-C16 alkylene, or NH—C(?O)—C2-C16 heteroakylene, wherein said alkylene and heteroalkylene are optionally substituted by 1, 2 or 3 groups independently selected from COOR? where R? is selected from H, methyl, ethyl or propyl. The invention further relates to immunogenic compositions comprising such glycoconjugates, and to methods for the preparation and use of such glycoconjugates and immunogenic compositions.

Abstract: A touch panel and method of manufacturing the same are disclosed. In one aspect, the touch panel includes a substrate, a first touch electrode line formed over the substrate and including a plurality of first touch electrodes which are electrically connected to each other, and a second touch electrode line formed to cross the first touch electrode line and being electrically insulated therefrom. The second touch electrode line can include a plurality of second touch electrodes which are electrically connected to each other. The touch panel can also include a plurality of connecting wires respectively connected to the first and second touch electrode lines. At least one of the first touch electrode line, the second touch electrode line, and the connecting wires can include at least one photosensitive conductive layer having a metal nanowire.

Abstract: The present invention relates generally to glycoconjugates comprising a saccharide covalently conjugated to a carrier protein through a spacer containing ((2-oxoethyl)thio)). In an aspect the invention provides oxo-eT linked glycoconjugates comprising a saccharide covalently conjugated to a carrier protein through a ((2-oxoethyl)thio) spacer having the formula (I): (I) wherein: A is a group (C?X)m wherein X is S or O and m is 0 or 1; B is a bond, O, or CH2; and when m is 0, B can also be (C?O); R is a C2-C16 alkylene, C2-C16 heteroalkylene, NH—C(?O)—C2-C16 alkylene, or NH—C(?O)—C2-C16 heteroalkylene, wherein said alkylene and heteroalkylene are optionally substituted by 1, 2 or 3 groups independently selected from COOR? where R? is selected from H, methyl, ethyl or propyl. The invention further relates to immunogenic compositions comprising such glycoconjugates, and to methods for the preparation and use of such glycoconjugates and immunogenic compositions.

Abstract: A display panel includes a first plurality of pixels in first pixel rows corresponding to a first plurality of gate lines, a second plurality of pixels in second pixel rows corresponding to a second plurality of gate lines, and a gate driver coupled to the first plurality of gate lines and the second plurality of gate lines, the gate driver is configured to in a first display mode, turn on the first plurality of pixels and the second plurality of pixels, and in a second display mode, turn off the first plurality of pixels and turn on the second plurality of pixels. By turning off the pixels in the plurality of rows disposed in the dark areas, the number of the pixels to be driven can be reduced while obtaining a sufficient pixel compensation time, thereby driving the display panel at high speed.

Abstract: A water collecting boundary block includes a body having an opened upper portion and a space portion formed therein, a grating which is seated on the body, and through which a plurality of rainwater inlets are formed, and a drain part formed at one side of a lower end of the body so as to be connected to the space portion, to provide water stored in the space portion to a ground.

Abstract: The invention provides eTEC linked glycoconjugates comprising a saccharide covalently conjugated to a carrier protein through a (2-((2-oxoethyl)thio)ethyl)carbamate (eTEC) spacer, immunogenic compositions comprising such glycoconjugates, and methods for the preparation and use of such glycoconjugates and immunogenic compositions.

Abstract: In one aspect, the invention relates to an immunogenic composition comprising modified O-polysaccharide molecules derived from E. coli lipopolysaccharides and conjugates thereof. Multivalent vaccines may be prepared by combining two or more monovalent immunogenic compositions for different E. coli serotypes. In one embodiment, the modified O-polysaccharide molecules are produced by a recombinant bacterium that includes a wzz gene.

Abstract: An inductor includes first and second coil patterns disposed in a single chip, and at least one common lead terminal electrically connected to respective end portions of the first and second coil patterns. The first and second coil patterns operate independently of each other, such that a range of a current passing through the first coil pattern and a range of a current passing through the second coil pattern are different from each other. The first and second coil patterns are coil patterns having different electrical characteristics.

Abstract: The present disclosure relates generally to methods of preparing glycoconjugates containing a saccharide conjugated to a carrier protein by use of stable nitroxyl radical related agent/oxidant as an oxidizing agent, to immunogenic compositions comprising such glycoconjugates, and to methods for the use of such glycoconjugates and immunogenic compositions.

Abstract: The present disclosure relates generally to methods of preparing glycoconjugates containing a saccharide conjugated to a carrier protein by use of stable nitroxyl radical related agent/oxidant as an oxidizing agent, to immunogenic compositions comprising such glycoconjugates, and to methods for the use of such glycoconjugates and immunogenic compositions.

Abstract: A touch panel includes: sensing electrodes respectively connected to sensing lines and arranged in a matrix form including columns in a first direction and rows in a second direction perpendicular to the first direction; pad electrodes respectively connected to pad lines and arranged in the second direction, a center of arrangement of the pad electrodes corresponding to a center of the rows of the sensing electrodes in the second direction; and a path determination unit connecting the sensing lines and the pad lines, the pad electrodes including: center pad electrodes; left pad electrodes; and right pad electrodes, and the pad lines including: center pad lines extended from the center pad electrodes; left pad lines extended from the left pad electrodes; and right pad lines extended from the right pad electrodes.