Abstract: The present disclosure relates to compounds that are Syk inhibitors or pharmaceutically acceptable salts or co-crystals thereof, and pharmaceutical compositions thereof, and to their use in the treatment of various disease states, including cancer and inflammatory conditions.

Abstract: The present disclosure provides processes and systems for heat integration in ethanol production. In one embodiment, a feed mixture is distilled with one or more distillation units to remove at least a portion of the water, and form a distillation unit bottom stream, a vaporous overhead stream, and a fusel oil stream. Molecular sieve units are regenerated by vacuum or a combination of vacuum and optionally a portion of the product stream to form one or more regenerate streams. A feed tank is configured to receive at least one selected from a condensed portion of the regenerate streams and a portion of a vaporous depressure stream, to form a feed stream. The energy contained in the depressure vapor is recovered by the depressure vapor contacting the feed tank and heating up at least one stream forwarded into the feed tank.

Abstract: A method for managing a thermal management device for a motor vehicle is disclosed. The device has a refrigerant circuit that circulates a refrigerant fluid. The circuit includes a main loop having, in the direction of circulation of the fluid, a compressor, a condenser configured to exchange heat energy with a first element, a first expansion device and a first evaporator configured to exchange heat energy with a second element. The device operates in a mode of strict cooling of the third element in which the condenser transfers heat energy to the first element and only the second evaporator absorbs heat energy from the third element. The method includes managing the open diameter of the first expansion device as a function of the ambient temperature so that the refrigerant fluid circulates inside the first evaporator, the open diameter of the first expansion device decreasing as the ambient temperature of the first element increases.

Abstract: The invention concerns a method for managing a thermal management device (1) for a motor vehicle, comprising the following steps: —increasing the speed of rotation of the compressor (3) to its maximum speed, —determining a modified setpoint temperature (T15-sp3) of the third element (300) greater than the first setpoint temperature (T15-sp1), so that the temperature of the second element (200) at the outlet of the first evaporator (11) tends towards its setpoint temperature (T11-sp), —adjusting the opening diameter of the second expansion device (13) so that the temperature of the third element (300) at the outlet of the second evaporator (15) reaches a modified setpoint temperature (T15-sp3), until the temperature of the second element (200) at the outlet of the first evaporator (11) reaches the setpoint temperature (T11-sp). The invention further relates to the thermal management device (1) for implementing said management method.

Abstract: A polymer, an electrolyte, and a lithium-ion battery employing the same are provided. The polymer is a product of a composition via a polymerization. The composition includes a first monomer and a second monomer. The first monomer has a structure represented by Formula (I) and the second monomer is fluorine-containing acrylate, fluorine-containing alkene, fluorine-containing epoxide, or a combination thereof. Particularly, n, m, and l are independently 1, 2, 3, 4, 5, or 6; and, R1, R2, R3, R4, R5 and R6 are as defined in the specification.

Abstract: The present invention relates to a method for controlling a thermal management device (1) of a motor vehicle comprising a refrigerant-fluid circuit comprising a compressor (3), a first heat exchanger (5), an expansion device (7) and the second heat exchanger (9), said thermal management device (1) further comprising an electric heating device (60), said control method involving, upon a starting of the thermal management device (1) from cold, the following steps: direct or indirect heating of the internal air flow (20) by the electrical heating device (60) alone until said internal air flow (200) reaches a target temperature and/or until a predetermined timer has run out, —when the internal air flow (200) has reached its target temperature and/or when the timer has run out, starting the compressor (3) so that the refrigerant-fluid circuit draws heat energy from the external air flow (100) at the second heat exchanger (9) and gives up said heat energy at the first heat exchanger (5).

Abstract: Fluid circulation valve, the said valve comprising a housing (1) and a body (2) for circulation of fluid, the said body (2) being located at least partially within the said housing (1), the said body (2) being attached to the housing (1) and having a passage (4) for fluid between the said body (2) and the said housing (1), the said valve further comprising a control member (30) that can be actuated electromagnetically, the said control member (30) being able to move with respect to the said body (2) so as to selectively open or close the said passage (4), the said body (2) having at least locally a tubular configuration at the said passage (4), the said control member (30) being able to slide along the said body (2) at least at the said passage (4).

Abstract: The present disclosure provides high-grade ethanol production systems and methods that increase energy efficiency as compared to typical systems and methods by minimizing undesired acetal formation. The provided ethanol production method may include a low boilers removal distillation column and/or a stripper column constructed to simultaneously remove at least a portion of the acetaldehyde and at least a portion of the acetal from a feed stream in the presence of water. In some aspects, a low boilers removal process may be followed by a water removal process, which may be followed by a high boilers removal process. Acidity (e.g., carbon dioxide) may also be removed from a feed stream prior to or during the low boilers removal process. By minimizing acetal production, the provided method minimizes the amount of energy that is required to remove acetal when producing high-grade ethanol.

Abstract: A cathode of a lithium ion battery is provided. The cathode of a lithium ion battery includes a collector material. A first electrode layer including a lithium manganese iron phosphate (LMFP) material is disposed on a surface of the collector material. A second electrode layer including an active material is disposed on the first electrode layer. The active material includes lithium nickel manganese cobalt oxide (NMC), lithium nickel cobalt aluminum oxide (NCA), lithium cobalt oxide (LCO), Li-rich cathode material, or a combination thereof.

Abstract: A reversible thermal management device for a motor vehicle includes a refrigerant fluid circuit containing a main loop which has, successively, a compressor, an internal condenser, a first expansion device and an external evaporator/condenser, a first, second, and third bypass branch, the third branch having at least one heat exchanger, a device for redirecting the refrigerant fluid coming from the internal condenser towards the first expansion device or the first bypass branch, a stop valve for the refrigerant fluid, arranged on the main loop, a first check valve arranged on the second bypass branch to block the refrigerant fluid coming from the internal condenser, a second check valve arranged on the main loop to block the refrigerant fluid coming from the evaporator/condenser, and a device for redirecting the refrigerant fluid coming from the first expansion device towards the at least one heat exchanger of the third bypass branch or the evaporator/condenser.

Abstract: A solid state electrolyte having a garnet type crystal structure is provided. The chemical composition of the solid state electrolyte includes lithium, lanthanum, zirconium, oxygen, and sulfur. The content of sulfur in the solid state electrolyte is between 5 mol % and 35 mol % based on the content of oxygen in the solid state electrolyte. A solid state battery including a positive electrode layer, a negative electrode layer, and a solid state electrolyte layer is also provided. The solid state electrolyte layer is disposed between the positive electrode layer and the negative electrode layer. The solid state electrolyte layer includes the solid state electrolyte.

Abstract: The present disclosure provides processes and systems for ethanol production. In one embodiment, a first beer column receives a first portion of a feed mixture including ethanol and water to form a first beer column bottom stream and a first beer column vaporous overhead stream. A beer column receives a second portion of the feed mixture. A first portion of the first beer column bottom stream is forwarded to a first beer column reboiler. A second portion of the first beer column bottom stream is forwarded to a plurality of evaporators. A condensed portion of the first beer column vaporous overhead stream is forwarded to a stripper column. The stripper column forms a feed stream, which is contacted with a separation system, thereby forming a permeate and a retentate. The permeate is forwarded directly to at least one selected from the first beer column and the stripper column.

Abstract: The present disclosure relates to compounds that are Syk inhibitors or pharmaceutically acceptable salts or co-crystals thereof, and pharmaceutical compositions thereof, and to their use in the treatment of various disease states, including cancer and inflammatory conditions.

Abstract: The invention concerns a method for controlling a system (1) for a motor vehicle, said system comprising at least: —an actuator, —a volatile memory (RAM) in which at least one item of position information of the actuator (IPRAM) is stored, —a long-term memory (EPROM) in which the following are stored: o at least one item of position information (IPROM) of the actuator, o an item of information relating to the powering down of the actuator (IHT), this item of information assuming a first value (v1) when the system has been powered down in a controlled manner and assuming a second value (v2) when the system has suffered a fault causing the current value of the position of the actuator stored in the volatile memory (RAM) to be deleted, in particular when the system has stopped being powered electrically as the result of an error, or communication between the system and a computer has been cut off as the result of an error.

Abstract: The present disclosure provides processes and systems for ethanol production. In one embodiment, a first beer column receives a first portion of a feed mixture including ethanol and water to form a first beer column bottom stream and a first beer column vaporous overhead stream. A beer column receives a second portion of the feed mixture. A first portion of the first beer column bottom stream is forwarded to a first beer column reboiler. A second portion of the first beer column bottom stream is forwarded to a plurality of evaporators. A condensed portion of the first beer column vaporous overhead stream is forwarded to a stripper column. The stripper column forms a feed stream, which is contacted with a separation system, thereby forming a permeate and a retentate. The permeate is forwarded directly to at least one selected from the first beer column and the stripper column.

Abstract: The present disclosure provides processes and systems for heat integration in ethanol production. In one embodiment, a feed mixture is distilled with one or more distillation units to remove at least a portion of the water, and form a distillation unit bottom stream, a vaporous overhead stream, and a fusel oil stream. Molecular sieve units are regenerated by vacuum or a combination of vacuum and optionally a portion of the product stream to form one or more regenerate streams. A feed tank is configured to receive at least one selected from a condensed portion of the regenerate streams and a portion of a vaporous depressure stream, to form a feed stream. The energy contained in the depressure vapor is recovered by the depressure vapor contacting the feed tank and heating up at least one stream forwarded into the feed tank.

Abstract: The present disclosure relates to compounds that are Syk inhibitors or pharmaceutically acceptable salts or co-crystals thereof, and pharmaceutical compositions thereof, and to their use in the treatment of various disease states, including cancer and inflammatory conditions.

Abstract: The present disclosure provides processes and systems for heat integration in ethanol production. In one embodiment, a feed mixture is distilled with one or more distillation units to remove at least a portion of the water, and form a distillation unit bottom stream, a vaporous overhead stream, and a fusel oil stream. Molecular sieve units are regenerated by vacuum or a combination of vacuum and optionally a portion of the product stream to form one or more regenerate streams. A feed tank is configured to receive at least one selected from a condensed portion of the regenerate streams and a portion of a vaporous depressure stream, to form a feed stream. The energy contained in the depressure vapor is recovered by the depressure vapor contacting the feed tank and heating up at least one stream forwarded into the feed tank.

Abstract: Doped titanium niobate is provided, which has a chemical structure of Ti(1-x)M1xNb(2-y)M2yO(7-z)Qz or Ti(2-x?)M1x?Nb(10-y?)M2y?O(29-z?)Qz?, wherein M1 is Li, Mg, or a combination thereof; M2 is Fe, Mn, V, Ni, Cr, or a combination thereof; Q is F, Cl, Br, I, S, or a combination thereof; 0?x?0.15; 0?y?0.15; 0.01?z?2; 0?x??0.3; 0?y??0.9; and 0.01?z??8.

Abstract: The present disclosure relates to compounds that are Syk inhibitors and to their use in the treatment of various disease states, including cancer and inflammatory conditions. In particular embodiments, the structure of the compounds is given by Formula I: wherein R1, R2, R3, and R4 are as described herein. The present disclosure further provides pharmaceutical compositions that include a compound of Formula I, or pharmaceutically acceptable salts or co-crystals thereof, and methods of using these compounds and compositions to treat conditions mediated by Syk.