Abstract: The present invention provides compounds of Formula (I), pharmaceutical compositions comprising these compounds and methods of using these compounds to provides a method of modulating a HSD17B13 protein for treatment of metabolic disease or liver condition, The present invention relates generally to compounds and pharmaceutical compositions useful as 17?-HSD13 inhibitors. Specifically, the present invention relates to compounds useful as inhibitors of 17?-HSD13 and methods for their preparation and use.

Abstract: Embodiments of the present disclosure relates to estimating downlink size for Quality of Experience (QoE) measurements. According to embodiments of the present disclosure, a terminal device is able to coordinate between an Access Stratum layer and an Application layer to associate the QoE configuration with the corresponding reports. In this way, enables unique identification of a single QoE configuration, as well as the corresponding QoE report at the terminal device.

Abstract: Method for measurement gap configuration comprising: sending a first message including a first measurement gap configuration based on a UE(10) new measurement gap capability from a first network device(20) to the UE(10); detecting at the first network device(20) whether a legacy gap assisted measurement is required for the UE(10); responsive to the legacy gap assisted measurement being required, sending a second message including a second measurement gap configuration based on a UE(10) legacy measurement gap capability from the first network device(20) to the UE(10); sending a third message indicating fallback of the UE(10) the legacy measurement gap capability from the first network device(20) to a second network device(30) in communication with the UE(10).

Abstract: Example embodiments of the present disclosure relate to devices, methods, apparatuses and computer readable storage media of dynamic signaling for a measurement gap. The method comprising receiving, from a second apparatus, information at least comprising an indication of a set of frequency bands associated with an measurement to be performed at the first apparatus; determining a requirement of a measurement gap for the measurement based on the information; and transmitting a message associated with the requirement to the second apparatus. In this way, a network controlled signaling management may be achieved, which may reduce the overhead of the signaling and improve the system performance.

Abstract: A method and system for improving e-commerce that is directed at improving landing pages for consumer products. Using long tail query phrases, the method and system generates more detailed landing pages that will assist in providing more information to consumers.

Abstract: Secondary loop air conditioning and heat pump systems include a reservoir with a capsule holding a phase change material.

Abstract: A spectral confocal measurement device includes a light source portion, configured to emit a broad-spectrum light beam with a certain wavelength range in a first predetermined path; an optical sampling portion, configured to converge the broad-spectrum light beam emitted from the light source portion on different measurement surfaces of an object to be measured, and output a reflected light in a second predetermined path that is different from a reverse direction of the first predetermined path; and a measurement portion, configured to receive and process the reflected light from the optical sampling portion to obtain a measurement result. The device can improve measurement accuracy and reduce production costs. In addition, a spectral confocal measurement method is also provided.

Abstract: A thermal management system and method for a vehicle, including: a heat-cold source thermal management circuit; an energy storage system thermal management circuit; a power electronics thermal management circuit; and a multi-port valve assembly coupled to the heat-cold source thermal management circuit, the energy storage system thermal management circuit, and the power electronics thermal management circuit and adapted to, responsive to an operating state of the vehicle, selectively couple and isolate the heat-cold source thermal management circuit, the energy storage system thermal management circuit, and the power electronics thermal management circuit to and from one another.

Abstract: In accordance with an embodiment, an apparatus may include at least one processor and at least one memory including computer program code. The at least one memory and the computer program code can be configured to, with the at least one processor, cause the apparatus to at least transmit a request for one or more cell global identities associated with one or more cells to a network entity. The at least one memory and the computer program code can be further configured to, with the at least one processor, cause the apparatus to at least update one or more neighbor relation tables based upon the received automatic neighbor relation related information. The at least one memory and the computer program code can be further configured to, with the at least one processor, cause the apparatus to at least transmit information based upon the updated one or more neighbor relation tables.

Abstract: The present invention provides compounds of Formula I: pharmaceutical compositions comprising these compounds and methods of using these compounds to treat or prevent a disease or disorder mediated by FXR and/or TGR5.

Abstract: A charging station assembly capable of generating and delivering a conditioned airflow while charging a battery of a vehicle. The temperature and flow rate of this conditioned airflow may be controlled based on the ambient conditions and battery status. The conditioned airflow may be directed toward an outside heat exchanger of a refrigerant system of the vehicle to enhance capacity. The conditioned airflow may also be routed to a battery pack for direct cooling or heating through additional ventilation system. In hot ambient conditions, the charging station provides cool air to facilitate battery cooling. In cold ambient conditions, the charging station provides hot air to facilitate battery heating. This charging station assembly shifts the load from the vehicle refrigerant system to the charging system, thereby improving battery thermal management capability, while eliminating the need for an oversized refrigerant system.

Abstract: Various disclosed embodiments include illustrative heating, ventilation, and air conditioning (HVAC) cases, HVAC systems, vehicles, and methods. In an illustrative embodiment, a heating, ventilation, and air conditioning (HVAC) system includes a case, a blower disposed in the case and configured to cause air to flow, a first heat exchanger disposed in the case and configured to heat the air, and an ambient extractor port defined in the case and configured to discharge to an ambient environment exterior to a structure the air provided to the ambient extractor port.

Abstract: Embodiments of the present disclosure relate to methods, apparatuses and computer readable storage media for a handover to dual connectivity. According to embodiments of the present disclosure, a terminal device receives, from a source network device, a connection reconfiguration message comprising configurations about a target master network device and a target secondary network device to be connected with the terminal device. The terminal device performs parallel random access to the target master network device and the target secondary network device. If the terminal device successfully connects to the target secondary network device but fails to connect to the target master network device, the terminal device will reconnect to the target master network device. In addition, the target secondary network device will indicate to the target master network device a result of the random access. As such, the solution can increase the success rate of the handover to dual connectivity.

Abstract: Various disclosed embodiments include illustrative heating, ventilation, and air conditioning (HVAC) devices, HVAC systems, vehicles, and methods. An illustrative HVAC system includes a case configured to at least partially recirculate air within the case, a blower disposed in the case and configured to cause air to flow, a first heat exchanger disposed in the case and configured to heat the air, and a second heat exchanger disposed in the case and configured to exchange heat with the air.

Abstract: Disclosed are methods for adjusting cell coverage of a multimedia broadcast multicast service. An example method (700) may include transmitting (701) data of a multimedia broadcast multicast service on a point-to-multipoint channel, monitoring (702) an uplink channel for information on an abnormal reception of the data, and adjusting (703) coverage of the point-to-multipoint channel based on the monitoring. Related apparatuses and computer readable media are also disclosed.

Abstract: The present invention relates to a method for producing a molybdenum alloy target, and solves the problem of low density and coarser grains of the molybdenum alloy targets in the prior art. The present invention comprises subjecting a mixed powder with a mass ratio depending upon the formula composition of a molybdenum alloy to a pre-press forming process to obtain a preformed molybdenum alloy target blank; placing the preformed molybdenum alloy target blank in a capsule and subjecting the capsule to processes of preheating for degassing and vacuum seal welding; subjecting the target blank to a hot isostatic pressing process to obtain a densified molybdenum alloy prefabricated target; removing the capsule; and subjecting the molybdenum alloy prefabricated target with the capsule removed to a temperature-rising and pressure-decreasing process, followed by finish machining to obtain a molybdenum alloy target.

Abstract: A method for measuring radiation intensity includes measuring the radiation intensity received by the protein in a radiation field based on degree of protein degradation in the radiation field, wherein the degree of degradation is a ratio of the molecular weight of the protein before and after irradiation. The measuring method is simple in operation, small in number of steps, small in error, and capable of measuring radiation doses of various radiation fields or even mixed radiation fields. Use of a biological dosimeter for measuring the radiation intensity by the method in a neutron capture therapy system can not only assess radiation contamination in the irradiation chamber, but also evaluate the neutron dose.

Abstract: The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, ester, stereoisomer, tautomer, solvate, hydrate, or combination thereof: which inhibit the Apoptosis signal-regulating kinase 1 (ASK-1), which associated with autoimmune disorders, neurodegenerative disorders, inflammatory diseases, chronic kidney disease, cardiovascular disease. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from ASK-1 related disease. The invention also relates to methods of treating an ASK-1 related disease in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The present invention specifically relates to methods of treating ASK-1 associated with hepatic steatosis, including non-alcoholic fatty liver disease (NAFLD) and non-alcohol steatohepatitis disease (NASH).

Abstract: The disclosure provides a display substrate, a driving method thereof and a display device. The display substrate includes: a base substrate with a hole in a hole region of the base substrate; a plurality of first signal lines, on a first side of the hole; and a plurality of second signal lines, on the other side of the hole distal to the first side; a plurality of first switch units, at terminals of the plurality of first signal lines proximal to the hole and electrically coupled to the plurality of first signal lines in one-to-one correspondence; a plurality of second switch units, at terminals of the plurality of second signal lines proximal to the hole; a plurality of connection lines comprising a plurality of first connection lines, a plurality of second connection lines and a plurality of third connection lines.

Abstract: The present disclosure provides an automatic separation apparatus for four fractions of heavy oil and a separation method thereof, wherein the apparatus includes a solvent reservoir tank (1), a separation unit for four fractions of heavy oil (100) and a receiving apparatus (9). The separation unit for four fractions of heavy oil (100) includes: a filter disc (4) having one end in communication with the solvent reservoir tank (1), and the other end in communication with an inlet of a pre-column flow path switching valve (5); a chromatographic column (6) having an inlet in communication with an outlet of the pre-column flow path switching valve (5), and an outlet in communication with an inlet of a post-column flow path switching valve (8). The receiving apparatus is in communication with an outlet of the post-column flow path switching valve (8).