Abstract: A fatty acid-releasing contact lens is described as well as method of manufacturing the same. The fatty acid-releasing contact lens comprises a glycerophospholipid loaded to the polymeric lens body and sustains the release of C12-C26 fatty acid after 1 hour in a release media comprising an sPLA2 enzyme solution. The fatty acid-releasing contact lens can be comfortably worn by a contact lens wearer and can increase the duration of comfortable lens wearing time and/or reduce lens awareness events in a contact lens wearer.

Abstract: The present disclosure provides a method for preparing lithium iron phosphate from ferric hydroxyphosphate, including: purifying ferrous sulfate to form a ferrous sulfate solution, adding hydrogen peroxide, phosphoric acid, an ammonium dihydrogen phosphate solution and ammonia water into the ferrous sulfate solution and then reacting to form a mixed slurry, holding the mixed slurry at a temperature for a period of time, and then washing with water and subjecting to press filtration to form ferric hydroxyphosphate precursors with different iron-phosphorus ratios; then flash drying, sintering at a high temperature, and pulverizing to obtain ferric hydroxyphosphate precursors with different iron-phosphorus ratios and different specific surface areas.

Abstract: The present application discloses a double-sided SiP packaging structure and a manufacturing method thereof, wherein the double-sided SiP packaging structure comprises a substrate, a first packaging structure arranged on the substrate, and a second packaging structure arranged below the substrate; the second packaging structure comprises a chip, interposer and a molding material; a conductive structure array is arranged on an upper surface of the interposer; the interposer is arranged below the substrate through the conductive structure array; a space region among a lower surface of the substrate, the chip and the interposer is filled with the molding material; a conductive bonding pad array is arranged on the lower surface of the interposer; and a groove is formed in a part of region between the conductive bonding pad and an edge contour of the interposer.

Abstract: A method for evaluating a downhole working condition of a PDC bit includes: performing an indoor test, including performing a drilling test in different full-sized cores by using the PDC bit with different degrees of abrasion and balling under condition of given WOB and rotational speed, to acquire change characteristics of a WOB, a rotational speed, a torque, a ROP and a bit vibration of the PDC bit in different time domains; improving and perfecting an existing prediction model and evaluation method for the downhole working condition through data obtained by the test to obtain the method; reading parameters of the WOB, the rotational speed, the torque and the ROP in real time during drilling; determining the downhole working condition of the PDC bit by using the method in the improving and perfecting.

Abstract: A system including one or more processors and one or more non-transitory computer-readable media storing computing instructions that, when executed on the one or more processors, perform certain acts. The acts can include obtaining an original load design for loading a trailer to deliver stacks of pallets to physical stores. The load design specifies a respective floor spot assignment for each of the stacks. The original load design satisfies center-of-gravity constraints. The acts also can include generating fluid groups of the stacks to form an initial fluid grouping. The acts additionally can include determining that the fluid groups do not collectively satisfy the center-of-gravity constraints. The acts further can include until the fluid groups collectively satisfy the center-of-gravity constraints, repeatedly determining one or more infeasible groups from the fluid groups, and adjusting at least one of the one or more infeasible groups to update the fluid groups.

Abstract: A method of fabricating an integrated circuit includes etching trenches in a first surface of a semiconductor layer. A trench dielectric layer is formed over the first surface and over bottoms and sidewalls of the trenches and a doped polysilicon layer is formed over the trench dielectric layer and within the trenches. The doped polysilicon layer is patterned to form a polysilicon bridge that connects to the polysilicon within the filled trenches and a blanket implant of a first dopant is directed to the polysilicon bridge and to the first surface. The blanket implant forms a contact region extending from the first surface into the semiconductor layer.

Abstract: The present invention discloses a recombinant collagen protein and its use in the cartilage repair matrix. The present invention discloses a recombinant collagen protein which contains the sequence shown in SEQ ID No. 1; the amino acid sequence of the stated recombinant collagen protein comprises N basic repetitive units; the basic repetitive unit contains n1 amino acid sequences with the following characteristic: G-Xaa1-Xaa2-G-E-Xaa3; the 3? end and the 5? end of the basic repetitive unit are connected to form the amino acid sequence with the above characteristic. The recombinant collagen protein claimed by the present invention has significant integrin binding activity, has the effect of promoting cell adhesion, proliferation, differentiation, and repairing cartilage tissue defects, etc, and it has promising prospects for application.

Abstract: One or more systems, devices, computer program products and/or computer-implemented methods of use provided herein relate to detecting a closed ring in a three-dimensional (3D) point cloud via cycle basis. A system can comprise a memory configured to store computer executable components; and a processor configured to execute the computer executable components stored in the memory, wherein the computer executable components can comprise a filtering component that can filter a first undirected graph of a three-dimensional (3D) point cloud, by eliminating one or more edges of the first undirected graph that are longer than an adaptive threshold, wherein filtering the first undirected graph can produce a second undirected graph; and a detection component that can detect a minimum cycle basis of the second undirected graph to determine a cycle path that can traverse an irregular annular shape that is represented by the 3D point cloud.

Abstract: A method, system, electronic device and storage medium for constructing locally convex feasible space are provided. The method includes acquiring a plurality of initial motion trajectory points, size information and surrounding obstacle information of a target vehicle; generating a quadtree map according to the above information; determining a target distance corresponding to each initial motion trajectory point according to the quadtree map; allocating locally convex feasible space to a first-type initial motion trajectory point by using the quadtree map, and allocating locally convex feasible space to a second-type initial motion trajectory point by using an improved convex feasible set algorithm. The first-type initial motion trajectory point is an initial motion trajectory point with the target distance greater than or equal to a set threshold; and the second-type initial motion trajectory point is an initial motion trajectory point with the target distance less than the set threshold.

Abstract: A pharmaceutical composition containing multi-target protein kinase inhibitor compounds, and the use thereof. The pharmaceutical composition contains compounds shown in formula II and formula A or formula B as active ingredients, and an excipient. The pharmaceutical composition has the characteristics of a simple preparation method, a smooth preparation process and suitability for industrial production. Moreover, an oral preparation prepared from the pharmaceutical composition, especially an oral solid preparation, has advantageous preparation properties such as dissolution rate and content uniformity, and excellent stability; and same is suitable for use and storage as a medicine.

Abstract: An oleic acid-releasing contact lens is described as well as method of manufacturing the same. The oleic acid-releasing contact lens comprises a glycerophospholipid comprising an oleoyl group at the sn-2 position and sustains the release of oleic acid in the presence of sPLA2 enzyme present in human tears. The oleic acid-releasing contact lens can increase the duration of comfortable lens wearing time and/or reduce lens awareness events in a symptomatic contact lens wearer.

Abstract: The present disclosure provides a bispecific antibody including a binding domain that binds to CD112R and a binding domain that binds to TIGIT, and the binding domain that binds to CD112R includes: HCDR1, HCDR2 and HCDR3 of the amino acid sequence set forth in SEQ ID NO: 1, and/or LCDR1, LCDR2 and LCDR3 of the amino acid sequence set forth in SEQ ID NO: 2; and the HCDR1, HCDR2, HCDR3, LCDR1, LCDR2 and LCDR3 are defined according to the Kabat, IMGT, Chothia, AbM or Contact numbering system. The present disclosure further provides a polynucleotide encoding the antibody, an expression vector, a host cell and a method for expressing and purifying the antibody, a pharmaceutical composition including the antibody of the present disclosure, and use of the bispecific antibody for treating cancer.

Abstract: The present invention relates to a method for preparing high-purity vanadium pentoxide from vanadium-bearing shale by all-wet process. The technical solution is: the “Gradient continuous leaching system of vanadium-bearing shale” is used to wet activate and compound leach vanadium-bearing shale to obtain vanadium-containing acid leachate. The “pH adjusting device of the vanadium-containing acid leachate” is used to adjust the pH of vanadium-containing acid leaching leachate. The post-treatment solution is subjected to hydroxime countercurrent extraction after oxidation, and the raffinate returns to the water using in the wet activation and electrodialysis after neutralization, and the loaded organic phase is regenerated by countercurrent reduction stripping. The regenerated organic phase directly returns to hydroxime countercurrent extraction.

Abstract: The present disclosure relates to the field of materials for uranium extraction from seawater (UES), and in particular, to a photothermal photocatalytic membrane for seawater desalination and uranium extraction and a preparation method therefor. The present disclosure provides a photothermal photocatalytic membrane for seawater desalination and uranium extraction and a preparation method therefor. The preparation method includes: fixing a treated carbon cloth to a glass plate, pouring a casting solution 1 onto the carbon cloth to form a first layer of film, forming a second layer of film using a casting solution 2, and putting the second layer of film into a first coagulation bath and a second coagulation bath in sequence to form the photothermal photocatalytic membrane. The photothermal photocatalytic membrane is supported by the carbon cloth, and a surface of the photothermal photocatalytic membrane is of a micro-nano structure.

Abstract: Systems and method directed to generating a stylized image are disclosed. In particular, the method includes, in a first data path, (a) applying first stylization to an input image and (b) applying enlargement to the stylized image from (a). The method also includes, in a second data path, (c) applying segmentation to the input image to identify a face region of the input image and generate a mask image, and (d) applying second stylization to an entirety of the input image and inpainting to the identified face region of the stylized image. Machine-assisted blending is performed based on (1) the stylized image after the enlargement from the first data path, (2) the inpainted image from the second data path, and (3) the mask image, in order to obtain a final stylized image.

Abstract: A terminal is disclosed including a selection unit that selects first resource candidates for sidelink transmission based on monitoring in a sensing window, and specifies second resource candidates by excluding specific periodic resources that are reserved by another terminal from the first resource candidates; and a transmission unit that performs sidelink transmission using a resource selected from the second resource candidates. In another aspect, a transmission method executed by a terminal is also disclosed.

Abstract: This application provides a method and apparatus for determining a resource in a relay system. By receiving resource indication information transmitted by an upper-level node, a first node determines the availability of a symbol in a first resource set located between a first hard resource set and a second hard resource set, and communicates with the upper-level node on the symbol based on the resource indication information to maximally improve resource utilization.

Abstract: A hierarchical health index evaluation method for an intelligent substation includes: obtaining a basic health index of a device based on static information and dynamic information of the device; obtaining a device correlation based on a communication connection relationship between the device and another device, and correcting the basic health index of the device based on the device correlation to obtain a health index of the device; obtaining a layer-based health index of a layer based on a device health index and a device importance weight of the layer; obtaining a whole-station health index of an intelligent substation based on a layer-based health index of each layer and a sum of device importance weights of each layer; and regulating the intelligent substation based on a health index of each device in the intelligent substation, the layer-based health index of each layer, and the whole-station health index.

Abstract: The present disclosure describes methods, systems and devices for determining sync raster. One method includes determining, by a user equipment (UE), a sync raster (SR) with a base station, wherein a first bandwidth of a synchronization signal or physical broadcast channel (SS/PBCH) block is larger than or equal to a minimum bandwidth in a narrowband, by: determining a frequency point of the SR; scanning the frequency point to obtain a scan result; and connecting with the base station based on the scan result. Another method includes determining a SR with a base station, wherein a first bandwidth of a SS/PBCH block is smaller than or equal to a minimum bandwidth in a narrowband, by: determining a frequency point of the SR; scanning the frequency point to obtain a scan result; and connecting with the base station based on the scan result.

Abstract: A method and system for decomposing cross-domain path planning of an amphibious vehicle.