Patents by Inventor Jing-Ru Weng

Jing-Ru Weng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8680133
    Abstract: Compounds and methods for treating cancer or inducing apoptosis in proliferating cells. The compounds are shown in formula I: wherein X is selected from hydroxyl, thiol, and amino; Y is selected from carboxyl and sulfonyl; R1, R2, R3, and R4 are selected from hydrogen, lower alkyl, and combinations thereof; R5, R6, and R7 are selected from hydrogen, halo, ni tro, amino, methoxy, and combinations thereof; and pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: March 26, 2012
    Date of Patent: March 25, 2014
    Assignee: The Ohio State University Research Foundation
    Inventors: Ching-Shih Chen, Jing-Ru Weng
  • Publication number: 20120184592
    Abstract: Compounds and methods for treating cancer or inducing apoptosis in proliferating cells. The compounds are shown in formula I: wherein X is selected from hydroxyl, thiol, and amino; Y is selected from carboxyl and sulfonyl; R1, R2, R3, and R4 are selected from hydrogen, lower alkyl, and combinations thereof; R5, R6, and R7 are selected from hydrogen, halo, nitro, amino, methoxy, and combinations thereof; and pharmaceutically acceptable salts thereof.
    Type: Application
    Filed: March 26, 2012
    Publication date: July 19, 2012
    Applicant: THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION
    Inventors: Ching-Shih Chen, Jing-Ru Weng
  • Patent number: 8153680
    Abstract: Compounds and methods for treating cancer or inducing apoptosis in proliferating cells. The compounds are shown in formula I: wherein X is selected from hydroxyl, thiol, and amino; Y is selected from carboxyl and sulfonyl; R1, R2, R3, and R4 are selected from hydrogen, lower alkyl, and combinations thereof; R5, R6, and R7 are selected from hydrogen, halo, nitro, amino, methoxy, and combinations thereof; and pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: August 25, 2009
    Date of Patent: April 10, 2012
    Assignee: The Ohio State University Research Foundation
    Inventors: Ching-Shih Chen, Jing-Ru Weng
  • Publication number: 20110054002
    Abstract: Compounds and methods for treating cancer or inducing apoptosis in proliferating cells. The compounds are shown in formula I: wherein X is selected from hydroxyl, thiol, and amino; Y is selected from carboxyl and sulfonyl; R1, R2, R3, and R4 are selected from hydrogen, lower alkyl, and combinations thereof; R5, R6, and R7 are selected from hydrogen, halo, nitro, amino, methoxy, and combinations thereof; and pharmaceutically acceptable salts thereof.
    Type: Application
    Filed: August 25, 2009
    Publication date: March 3, 2011
    Applicant: The Ohio State University Research Foundation
    Inventors: Ching-Shih Chen, Jing-Ru Weng
  • Patent number: 7807705
    Abstract: Compounds and methods for treating cancer and inducing apoptosis in unwanted rapidly proliferating cells. The compounds are shown in formula I: wherein X is hydroxyl or amino; Y is carboxyl or sulfonyl; R1, R2, R3, and R4 can be the same or different and are selected from hydrogen, halogen, methoxy, trifluoromethyl, hydroxyl and combinations thereof, R5, R6, and R7 may be the same or different and are selected from hydrogen, chloro, bromo, nitro, phenyl, amino, methoxy, and combinations thereof, and derivatives or metabolites thereof.
    Type: Grant
    Filed: May 9, 2008
    Date of Patent: October 5, 2010
    Assignee: The Ohio State University Research Foundation
    Inventors: Ching-Shih Chen, Dasheng Wang, Jing-Ru Weng
  • Publication number: 20080300291
    Abstract: Compounds and methods for treating cancer and inducing apoptosis in unwanted rapidly proliferating cells. The compounds are shown in formula I: wherein X is hydroxyl or amino; Y is carboxyl or sulfonyl; R1, R2, R3, and R4 can be the same or different and are selected from hydrogen, halogen, methoxy, trifluoromethyl, hydroxyl and combinations thereof, R5, R6, and R7 may be the same or different and are selected from hydrogen, chloro, bromo, nitro, phenyl, amino, methoxy, and combinations thereof, and derivatives or metabolites thereof.
    Type: Application
    Filed: May 9, 2008
    Publication date: December 4, 2008
    Applicant: The Ohio State University Research Foundation
    Inventors: Ching-Shih Chen, Dasheng Wang, Jing-Ru Weng
  • Patent number: 7367199
    Abstract: A method for automatically balancing air conditioning outdoor heat exchange detects a piping measured value of each piping equipment through a detection unit and compares the piping measured value with a set operation mode selected by users and a set value. Airflow amount of adjustable air vents is adjustable according to the comparing result. The method includes the steps of: (1) selecting an operation mode, (2) selecting an effective piping measured value which serves as the basis to operate an air fan device, and (3) based on the piping measured value corresponding to each exchange equipment to open the air vents at a desired degree. By means of the aforesaid method and system, the air conditioning outdoor heat exchange system can be balanced automatically.
    Type: Grant
    Filed: February 11, 2005
    Date of Patent: May 6, 2008
    Assignee: Cohand Technology Co., Ltd.
    Inventors: Kuo-Liang Weng, Jing-Ru Weng
  • Publication number: 20070163292
    Abstract: A thin refrigeration air conditioner has a casing which houses a thin heat exchanger, an air intake chamber, an air exit chamber, a side chamber and an air port baffle. The thin heat exchanger in cooperative with the air port baffle or a return air branch port can control airflow to maintain a high temperature difference and low flow rate operation while the air and refrigerant flow through the thin heat exchanger to perform heat exchange process. Return airflow and airflow delivery can be maintained in an optimal temperature difference condition according to energy requirement of the air conditioning zone. Thus it can provide a most comfortable condition and also save energy. It also takes less installation space and improves airflow distribution.
    Type: Application
    Filed: January 18, 2006
    Publication date: July 19, 2007
    Inventors: Kuo-Liang Weng, Jing-Ru Weng, Jing-Ying Tsai
  • Publication number: 20070068668
    Abstract: A water total heat exchange energy reclaiming apparatus includes a first chassis and a second chassis. The first chassis includes a first air duct, a water vaporizing device, a first heat exchange coil and a first fan. The second chassis includes a second air duct, a cold water heat exchange tube, a second heat exchange coil and a second fan. The first chassis and the second chassis are separated. Installation can be done according to environment requirements and is more convenient. Mixing of discharge airflow and return airflow can be prevented. Thus air quality of the environment can be improved and energy saving can be achieved.
    Type: Application
    Filed: September 28, 2005
    Publication date: March 29, 2007
    Inventors: Kuo-Liang Weng, Jing-Ru Weng
  • Publication number: 20060205808
    Abstract: The fresh seeds obtained from the fresh fruits of Garcinia subelliptica, were extracted with chloroform at room temperature. The CHCl3 extract was concentrated under reduced pressure to afford a brown residue. This residue was subjected to column chromatography (silica gel) and eluted with appropriate solvent system to give two phloroglucinol derivatives (Compounds 1 and 4). Compound 1 exhibited potent inhibitory effects on the release of ?-glucuronidase and lysozyme from rat neutrophils stimulated with formyl-Met-Leu-Phe(fMLP)/cyto-chalasin B (CB). Compound 1 also exhibited potent inhibitory effect on the superoxide anion generation in rat neutrophils stimulated with fMLP/CB. Compound 4 exhibited potent inhibitory effect on NO production in lipopolysaccharide (LPS)/interferon-? (IFN-?)-activation in N9 cells. These Compounds may be developed as anti-inflammatory, anti-cancer agent, cure for ageing, and Alzheimer's disease treatment drugs.
    Type: Application
    Filed: March 10, 2005
    Publication date: September 14, 2006
    Applicant: Kaohsiung Medical University
    Inventors: Chun-Nan Lin, Jih-Pyang Wang, Jing-Ru Weng
  • Publication number: 20060179857
    Abstract: A method for automatically balancing air conditioning outdoor heat exchange detects a piping measured value of each piping equipment through a detection unit and compares the piping measured value with a set operation mode selected by users and a set value. Airflow amount of adjustable air vents is adjustable according to the comparing result. The method includes the steps of: (1) selecting an operation mode, (2) selecting an effective piping measured value which serves as the basis to operate an air fan device, and (3) based on the piping measured value corresponding to each exchange equipment to open the air vents at a desired degree. By means of the aforesaid method and system, the air conditioning outdoor heat exchange system can be balanced automatically.
    Type: Application
    Filed: February 11, 2005
    Publication date: August 17, 2006
    Inventors: Kuo-Liang Weng, Jing-Ru Weng