Patents by Inventor Jing Ying Evelina Han

Jing Ying Evelina Han has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Electrochemical detection of microorganisms
    Patent number: 10179927
    Abstract: The present invention provides a method for determining the presence of a microorganism in a sample using an electrochemically active reporter, wherein the method comprises (a) contacting the sample with an electrochemically active reporter, wherein the electrochemically active reporter is a conjugate comprising a sugar moiety and a redox active reporter moiety that are covalently linked such that the covalent bond can be enzymatically cleaved in the presence of the microorganism by an enzyme expressed by the microorganism, wherein the redox active reporter moiety is selected from the group consisting of resorufin and compounds of formula (I) as defined herein, under conditions that allow enzymatic cleavage of the covalent bond between the sugar moiety and the redox active reporter moiety and reduction of the redox active report moiety in the presence of the microorganism; (b) electrochemically determining the released redox active reporter moiety; and (c) determining the presence of the microorganism and, op
    Type: Grant
    Filed: August 24, 2015
    Date of Patent: January 15, 2019
    Assignees: Nanyang Technological University, National University of Singapore
    Inventors: Jamie Hinks, Jing Ying Evelina Han, Say Chye Joachim Loo, Stefan Wuertz
  • ELECTROCHEMICAL DETECTION OF MICROORGANISMS
    Publication number: 20180016618
    Abstract: The present invention provides a method for determining the presence of a microorganism in a sample using an electrochemically active reporter, wherein the method comprises (a) contacting the sample with an electrochemically active reporter, wherein the electrochemically active reporter is a conjugate comprising a sugar moiety and a redox active reporter moiety that are covalently linked such that the covalent bond can be enzymatically cleaved in the presence of the microorganism by an enzyme expressed by the microorganism, wherein the redox active reporter moiety is selected from the group consisting of resorufin and compounds of formula (I) as defined herein, under conditions that allow enzymatic cleavage of the covalent bond between the sugar moiety and the redox active reporter moiety and reduction of the redox active report moiety in the presence of the microorganism; (b) electrochemically determining the released redox active reporter moiety; and (c) determining the presence of the microorganism and, op
    Type: Application
    Filed: August 24, 2015
    Publication date: January 18, 2018
    Inventors: Jamie Hinks, Jing Ying Evelina Han, Say Chye Joachim Loo, Stefan Wuertz