Abstract: The technical field of active substance preparations is belonged to, and provided are astaxanthin pickering emulsion with colon targeted delivery function, and a preparation method and application method thereof. The preparation method includes the following steps: S1, reparation of deacetylated-oxidized chitin nanofiber (DE-TO-ChNF)/carboxymethyl konjac glucomannan (CMKGM) nanogel; S2, preparation of astaxanthin oil phase; and S3, preparation astaxanthin pickering emulsion. Natural polysaccharide derivatives DE-TO-ChNF and CMKGM are used as raw materials, and stable crosslinking between covalent bonds and non-covalent bonds are formed between molecules in a composite system through the NHS/EDC, so as to form a stable nanogel. Then the nanogel is used as emulsifier and flaxseed oil rich in astaxanthin is used as oil phase to prepare the astaxanthin pickering emulsion by homogenization.

Abstract: A method is provided for evaluating an effect of classifying a fuzzy attribute of an object, the fuzzy attribute referring to an attribute, a boundary between two similar ones of a plurality of categories of which is blurred, wherein the method includes: generating a similarity-based ranked confusion matrix, which comprises: based on similarities of K categories of the fuzzy attribute of the object, ranking the K categories, where K is an integer greater than or equal to 2, generating a K×K all-zero initialization matrix, wherein an abscissa and an ordinate of the initialization matrix respectively represent predicted values and true values of the similarity-based ranked categories of the fuzzy attribute, and based on the true values and the predicted values of the category of the fuzzy attribute for the multiple object samples, updating values of corresponding elements in the initialization matrix; and displaying the similarity-based ranked confusion matrix.

Abstract: A porous biochar for improving heavy pollution and a method for producing the same. Said porous biochar is prepared as follows: arrowhead, which has excellent enrichment of lead, is used to absorb heavy metal lead in polluted water or artificial wetlands, simultaneously absorb heavy metal cadmium, thereafter is dried and treated as a biomass, and then the biomass is calcined in stages with a passivating agent in a high temperature environment, so as to heavy metals such as lead and cadmium be stably coated or enriched in a biochar, which is mixed with Pseudomonas aeruginosa having high resistant, to obtain the porous biochar; the porous biochar has high specific surface area, high porosity and excellent mechanical properties, is very stable under different acid-base environments and oxidizing conditions.

Abstract: A method of generating a stylized 3D avatar is provided. The method includes receiving an input image of a user, generating, using a generative adversarial network (GAN) generator, a stylized image, based on the input image, and providing the stylized image to a first model to generate a first plurality of parameters. The first plurality of parameters include a discrete parameter and a continuous parameter. The method further includes providing the stylized image and the first plurality of parameters to a second model that is trained to generate an avatar image, receiving, from the second model, the avatar image, comparing the stylized image to the avatar image, based on a loss function, to determine an error, updating the first model to generate a second plurality of parameters that correspond to the first plurality of parameters, based on the error, and providing the second plurality of parameters as an output.

Abstract: Provided is a compound of formula I or a pharmaceutically acceptable salt, enantiomer, diastereomer, tautomer, solvate, isotopic substituent, polymorph, prodrug, or metabolite thereof. Also provided is a method for preparing the compound of formula I. The compound of formula I has higher inhibitory activity against SHP2, and thus can be used to prevent or treat a disease related to SHP2.

Abstract: A negative electrode including a negative electrode active material layer and an additive. The additive includes a metal sulfide. The additive is distributed in the negative electrode active material layer, and/or distributed on the surface of the negative electrode active material layer. The negative electrode effectively improves the performance of the lithium ion battery, and greatly improves the capacity and cycle performance of the lithium ion battery.

Abstract: A method for controlling a device for automatically adjusting an airway opening body position is provided. The device includes a horizontal base plate, a head support block, a back support plate, a neck support apparatus, a head cover assembly, and a programmable logic controller (PLC). The neck support apparatus is positioned between the head support block and the back support plate. The PLC is configured to controls a stroke of an electric cylinder according to the following equations: ?=1.235?+?, and ?=KX+B+C, where ? is a body position angle, the body position angle is an angle between a positive projection line of a connecting line from a mandibular angle to an external acoustic meatus on a symmetrical surface of a human body and the back support plate, and ? is a preset value ranging from 90° to 100°.

Abstract: An object detection model generation method as well as an electronic device and a computer readable storage medium using the same are provided. The method includes: during the iterative training of the to-be-trained object detection model, the detection accuracy of the iteration nodes of the object detection model is sequentially determined according to the node order, and the mis-detected negative samples of the object detection model at the iteration nodes with the detection accuracy less than or equal to a preset threshold are enhanced. Then the object detection model is trained at the iteration node based on the enhanced negative samples and a first amount of preset training samples. After the training at the iteration nodes are completed, it returns to the step of sequentially determining the detection accuracy of the iteration nodes of the object detection model until the training of the object detection model is completed.

Abstract: The present disclosure provides a method for processing defect information of a product, which includes the following steps of: acquiring defect information on a current film layer and defect information on historical film layers; determining whether defect information exists at a target location of the historical film layer if defect information exists at a target location of the current film layer; if defect information exists for a corresponding location to the target location in at least one of the historical film layers, deleting the defect information detected at the target location in the current film layer; and if no defect information exists for the target location in any of the historical film layers, retaining the defect information detected at the target location in the current film layer.

Abstract: An image processing method includes acquiring a set of image samples for training an attribute recognition model, wherein the set of image samples includes a first subset of image samples with category labels and a second subset of image samples without category labels; training a sample prediction model using the first subset of image samples, and predicting categories of the image samples in the second subset of image samples using the trained sample prediction model; determining a category distribution of the set of image samples based on the category labels of the first subset of image samples and the predicted categories of the second subset of image samples; and acquiring a new image sample if the determined category distribution does not conform to the expected category distribution, and adding the acquired new image sample to the set of image samples.

Abstract: The present invention relates to an antioxidant culture method and antioxidant auxiliary equipment. The antioxidant cultivation method comprises: providing an electrolytic hydrogen generator comprising an anode, a cathode and a membrane between the cathode and the anode, the electrolytic hydrogen generator being connected with a bioreactor; inputting the culture medium in the bioreactor to the cathode and inputting a pure water to the anode; and providing an electric current to the electrolytic hydrogen generator to output a hydrogen from the cathode so as to dissolve the hydrogen in the culture medium of the bioreactor.

Abstract: A ROCK inhibitor represented by formula (I), and a preparation method therefor and a use thereof are provided. The ROCK inhibitor has excellent ROCK inhibition activity, particularly shows good selective inhibition on ROCK2 kinase, has good safety and metabolic stability, and is high in bioavailability. The preparation method for the ROCK inhibitor is simple, and the ROCK inhibitor is easy to purify, and therefore has a good application prospect.

Abstract: An application of a compound using intra-cyclic peroxo-bridged sesquiterpenes as a parent nucleus in metabolism-related fatty liver diseases is provided. The compound using intra-cyclic peroxo-bridged sesquiterpenes as the parent nucleus has the structure shown in Formula I, where A denotes O, —OH, OCH3, —OCH2CH3, or —OC4H5O3. The compound using intra-cyclic peroxo-bridged sesquiterpenes as the parent nucleus is configured for preparing a drug or a composition for treating metabolism-related fatty liver diseases. The present invention demonstrates that the compound using intra-cyclic peroxo-bridged sesquiterpenes as the parent nucleus can improve the function of mitochondria. in liver cells and enhance the fatty acid ?-oxidation capacity thereof and can be used for the treatment of metabolic dysfunction due to mitochondrial dysfunction, as well as the resulting liver fat accumulation, inflammation, and fibrotic lesions.

Abstract: Provided herein are 2?-O-methyl 3?phosphorothioate (MS)-modified synthetic nucleic acid molecules (single guide RNAs (sgRNAs)) in combination with a base editor as a ribonucleoprotein (RNP) complex for an electroporation-based ex vivo targeted gene disruption of the BCL11A erythroid enhancer's +55, +58, or +62, functional regions. Also provided herein are methods relating to the treatment of hemoglobinopathies by reinduction of fetal hemoglobin levels.

Abstract: Some examples herein include systems and methods of creating standards of gemstones of various classifications, which may display certain characteristics of the various classifications when excited by ultraviolet radiation and fluoresce in response. In some examples, a set of standards are created using fluorescent material, filters, and a radiation source to compare against a sample gemstone. In some examples, specific Light Emitting Diodes are selected to illuminate the gemstone samples under analysis.

Abstract: A casing hanger and annulus sealing device running tool for deepwater drilling and a method for using the same. The running tool includes a spindle connected to a hollow suspension structure via a torque transmission structure, one end of the spindle slidably passes through a hollow piston, the suspension structure rotates with the spindle and slide along the piston, the inner cavity of the torque transmission structure communicates with that of the suspension structure to form a piston cavity; the piston cavity and the piston form a hydraulic piston structure; and one end of the suspension structure away from the torque transmission structure can rotatably hook to and lift upward to release the annulus sealing device, and one end of the piston away from the torque transmission structure can radially expand to hook to the casing hanger and can radially contract to release the casing hanger.

Abstract: The present invention provides an ascorbate peroxidase mutant MaAPX1M36K and an application thereof, belonging to the technical field of biotechnology. An amino acid sequence of the mutant MaAPX1M36K of the present invention is shown in SEQ ID NO. 3. In the present invention, the mutant MaAPX1M36K reconstruction protein is obtained by the method of prokaryotic expression. It is found that the mutant MaAPX1M36K improves catalytic efficiency by nearly 5 times, providing a technical reference for further study and application of APX1.

Abstract: The present disclosure discloses a method and a device for measuring flatness of a flexible photovoltaic module, comprising: a measurement platform configured to fix a to-be-measured flexible photovoltaic module, height measurers respectively corresponding to wave crests and wave troughs on the to-be-measured flexible photovoltaic module, the plurality of height measurers being located above the measurement platform, and a lift rack on which the plurality of height measurers are disposed.

Abstract: Provided are a device and method for detecting a photovoltaic module. An exemplary device for detecting a photovoltaic module may comprise a light source and a projection display unit provided on opposite sides of a photovoltaic module to be detected, respectively. Further, the projection display unit may be configured to display a projection of the photovoltaic module to be detected, generated under illumination of the light source. In devices and methods for detecting a photovoltaic module provided by embodiments herein, under illumination of the light source, the projection of the photovoltaic module to be detected may be displayed on the projection display unit, and bent corner(s) of the photovoltaic module to be detected can also be clearly displayed, which enables an accurate and quick selection of defective photovoltaic modules. Moreover, the removal of the defective photovoltaic modules greatly increases production yield of final products assembled from the photovoltaic modules.

Abstract: A wet leakage current test system for a photovoltaic component is disclosed having a liquid pool and a voltage-withstanding insulation tester as well as a first storage rack, a lifting actuator, a second storage rack, a drying apparatus and an electrical protection device; the first storage rack is arranged above the liquid pool, and is mechanically connected with the lifting actuator; the lifting actuator is configured to drive the first storage rack to descend into the liquid pool or ascend above the liquid pool; the drying apparatus is mounted on the second storage rack, for blowing air to a front surface and a back surface of the photovoltaic component laid flat on the second storage rack; and the electrical protection device is in electrical signal connection with the voltage-withstanding insulation tester, for disabling a voltage output from the voltage-withstanding insulation tester in the case that the operator operates in a high voltage region, and/or for cutting off a power source of the voltage-wit