Patents by Inventor Jinghan Ye
Jinghan Ye has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11798205Abstract: A non-transitory computer-readable medium stores instructions readable and executable by a workstation (18) including at least one electronic processor (20) to perform an image reconstruction method (100). The method includes: determining a weighting parameter (13) of an edge-preserving regularization or penalty of a regularized image reconstruction of an image acquisition device (12) for an imaging data set obtained by the image acquisition device; determining an edge sensitivity parameter (?) of the edge-preserving algorithm for the imaging data set obtained by the image acquisition device; and reconstructing the imaging data set obtained by the image acquisition device to generate a reconstructed image by applying the regularized image reconstruction including the edge-preserving regularization or penalty with the determined weighting and edge sensitivity parameters to the imaging data set obtained by the image acquisition device.Type: GrantFiled: January 2, 2019Date of Patent: October 24, 2023Assignee: KONINKLIJKE PHILIPS N.V.Inventors: Chuanyong Bai, Andriy Andreyev, Bin Zhang, James Gurian, Zhiqiang Hu, Yu-Lung Hsieh, Shekhar Dwivedi, Jinghan Ye, Xiyun Song, Michael Allen Miller
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Patent number: 11428829Abstract: A non-transitory computer-readable medium stores instructions readable and executable by a workstation (18) including at least one electronic processor (20) to perform an image reconstruction method (100) to reconstruct list mode data acquired over a frame acquisition time using a plurality of radiation detectors (17) in which the events of the list mode data is timestamped.Type: GrantFiled: January 30, 2019Date of Patent: August 30, 2022Assignee: KONINKLIJKE PHILIPS N.V.Inventors: Xiyun Song, Chuanyong Bai, Jinghan Ye, Andriy Andreyev, Zhiqiang Hu
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Patent number: 11393138Abstract: A non-transitory storage medium stores instructions readable and executable by an electronic processor (20) to perform a method (100) for estimating singles rates for detectors (16) of a detector array (14) of a positron emission tomography (PET) imaging device (12).Type: GrantFiled: September 20, 2018Date of Patent: July 19, 2022Assignee: KONINKLIJKE PHILIPS N.V.Inventors: Xiyun Song, Jinghan Ye, Andriy Andreyev, Chuanyong Bai, Zhiqiang Hu
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Patent number: 11354832Abstract: A non-transitory computer readable medium storing instructions readable and executable by an imaging workstation (14) including at least one electronic processor (16) to perform a dataset generation method (100) operating on emission imaging data acquired of a patient for one or more axial frames at a corresponding one or more bed positions, the method comprising: (a) identifying a frame of interest from the one or more axial frames; (b) generating simulated lesion data by simulating emission imaging data for the frame of interest of at least one simulated lesion placed in the frame of interest; (c) generating simulated frame emission imaging data by simulating emission imaging data for the frame of interest of the patient; (d) determining a normalization factor comprising a ratio of the value of a quantitative metric for the simulated patient data and the value of the quantitative metric for the emission imaging data acquired of the same patient for the frame of interest; and (e) generating a hybrid data setType: GrantFiled: May 1, 2018Date of Patent: June 7, 2022Assignee: KONINKLIJKE PHILIPS N.V.Inventors: Chuanyong Bai, Andriy Andreyev, Xiyun Song, Jinghan Ye, Bin Zhang, Shekhar Dwivedi, Yanfei Mao, Zhiqiang Hu
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Patent number: 11282242Abstract: A non-transitory computer-readable medium stores instructions readable and executable by a workstation (18) including at least one electronic processor (20) to perform an image reconstruction method (100). The method includes: generating, from received imaging data, a plurality of intermediate images reconstructed without scatter correction from data partitioned into different energy windows; generating a fraction of true counts and a fraction of scatter events in the generated intermediate images; generating a final reconstructed image from the intermediate images, the fraction of true counts in the intermediate images, and the fraction of scatter counts in the intermediate images; and at least one of controlling the non-transitory computer readable medium to store the final image and control a display device (24) to display the final image.Type: GrantFiled: January 24, 2019Date of Patent: March 22, 2022Assignee: KONINKLIJKE PHILIPS N.V.Inventors: Jinghan Ye, Xiyun Song, Chuanyong Bai, Andriy Andreyev, Chi-Hua Tung, Zhiqiang Hu
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Patent number: 11270479Abstract: In an emission imaging method, emission imaging data are acquired for a subject using an emission imaging scanner (10) including radiation detectors (12). The emission imaging data are reconstructed to generate a reconstructed image by executing a constrained optimization program including a measure of data fidelity between the acquired emission imaging data an a reconstruct-image transformed by a data model of the imaging scanner to emission imaging data. During the reconstructing, each iteration of the constrained optimization program is constrained by an image variability constraint. The reconstructed image is displayed the reconstructed image on a display device. The emission imaging may be positron emission tomography (PET) imaging data, optionally acquired using a sparse detector array. The image variability constraint may be a constraint that an image total variation (image TV) of a latent image defined using a Gaussian blurring matrix be less than a maximum value.Type: GrantFiled: February 13, 2017Date of Patent: March 8, 2022Assignees: KONINKLIJKE PHILIPS N.V., UNIVERSITY OF CHICAGOInventors: Xiaochuan Pan, Jinghan Ye, Amy Perkins, Chi-Hua Tung, Zheng Zhang
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Patent number: 11234667Abstract: A non-transitory storage medium storing instructions readable and executable by an imaging workstation (18) including at least one electronic processor (20) to perform an image reconstruction method (100). The method includes: receiving emission imaging data (22) from an image acquisition device (12) wherein the emission imaging data has been filtered using an acquisition energy passband (18); generating filtered imaging data by filtering the emission imaging data with a second energy passband (90) that is narrower than an acquisition energy passband; reconstructing the filtered imaging data to generate an intermediate image; estimating one or more scatter correction factors (SCFs) from the intermediate image; and reconstructing the emission imaging data corrected with the estimated SCFs to generate a reconstructed image.Type: GrantFiled: August 30, 2018Date of Patent: February 1, 2022Assignee: KONINKLIJKE PHILIPS N.V.Inventors: Andriy Andreyev, Xiyun Song, Jinghan Ye, Chuanyong Bai, Zhiqiang Hu, Douglas B. McKnight
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Publication number: 20210375009Abstract: A non-transitory computer-readable medium stores instructions readable and executable by a workstation (18) including at least one electronic processor (20) to perform an image reconstruction method (100). The method includes: generating, from received imaging data, a plurality of intermediate images reconstructed without scatter correction from data partitioned into different energy windows; generating a fraction of true counts and a fraction of scatter events in the generated intermediate images; generating a final reconstructed image from the intermediate images, the fraction of true counts in the intermediate images, and the fraction of scatter counts in the intermediate images; and at least one of controlling the non-transitory computer readable medium to store the final image and control a display device (24) to display the final image.Type: ApplicationFiled: January 24, 2019Publication date: December 2, 2021Inventors: Jinghan YE, Xiyun SONG, Chuanyong BAI, Andriy ANDREYEV, Chi-Hua TUNG, Zhiqiang HU
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Publication number: 20210366165Abstract: A non-transitory computer-readable medium stores instructions readable and executable by a workstation (18) including at least one electronic processor (20) to perform an image reconstruction method (100).Type: ApplicationFiled: January 24, 2019Publication date: November 25, 2021Inventors: Xiyun SONG, Jinghan YE, Yanfei MAO, Chuanyong BAI, Andriy ANDREYEV, Gregory DOUGHTY, Leonid ROMANOV, Zhiqiang HU
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Patent number: 11175418Abstract: A non-transitory computer-readable medium storing instructions readable and executable by a workstation (18) including at least one electronic processor (20) to perform a quality control (QC) method (100). The method includes: receiving a current QC data set acquired by a pixelated detector (14) and one or more prior QC data sets acquired by the pixelated detector; determining stability levels of detector pixels (16) of the pixelated detector over time from the current QC data set and the one or more prior QC data sets; labeling a detector pixel of the pixelated detector as dead when the stability level determined for the detector pixel is outside of a stability threshold range; and displaying, on a display device (24) operatively connected with the workstation, an identification (28) of the detector pixels labelled as dead.Type: GrantFiled: September 12, 2018Date of Patent: November 16, 2021Assignee: KONINKLIJKE PHILIPS N.V.Inventors: Chuanyong Bai, Andriy Andreyev, Shushen Lin, Bin Zhang, Michael Allen Miller, Xiyun Song, Jinghan Ye, Shekhar Dwivedi, Zhiqiang Hu, Yu-Lung Hsieh, Ilya Brodskiy, Thomas Christopher Bulgrin, Yang-Ming Zhu, Douglas B. McKnight
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Publication number: 20210209817Abstract: In an emission imaging method, emission imaging data are acquired for a subject using an emission imaging scanner (10) including radiation detectors (12). The emission imaging data are reconstructed to generate a reconstructed image by executing a constrained optimization program including a measure of data fidelity between the acquired emission imaging data an a reconstruct-image transformed by a data model of the imaging scanner to emission imaging data. During the reconstructing, each iteration of the constrained optimization program is constrained by an image variability constraint. The reconstructed image is displayed the reconstructed image on a display device. The emission imaging may be positron emission tomography (PET) imaging data, optionally acquired using a sparse detector array. The image variability constraint may be a constraint that an image total variation (image TV) of a latent image defined using a Gaussian blurring matrix be less than a maximum value.Type: ApplicationFiled: February 13, 2017Publication date: July 8, 2021Inventors: Xiaochuan PAN, Jinghan YE, Amy PERKINS, Chi-Hua TUNG, Zheng ZHANG
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Patent number: 11049230Abstract: Image processing performed by a computer (22) includes iterative image reconstruction or refinement (26, 56) that produces a series of update images ending in an iteratively reconstructed or refined image. A difference image (34, 64) is computed between a first update image (30, 60) and a second update image (32, 62) of the series. The difference image is converted to a feature image (40) and is used in the iterative processing (26, 56) or in post-processing (44) performed on the iteratively reconstructed or refined images or images from different reconstruction or refinement techniques. In another embodiment, first and second image reconstructions (81, 83) are performed to generate respective first and second reconstructed images (80, 82). A difference image (84) is computed between two images each selected from the group: the first reconstructed image, an update image of the first reconstruction, the second reconstructed image, and an update image of the second reconstruction.Type: GrantFiled: August 22, 2017Date of Patent: June 29, 2021Assignee: KONINKLIJKE PHILIPS N.V.Inventors: Chuanyong Bai, Andriy Andreyev, Bin Zhang, Yang-Ming Zhu, Xiyun Song, Jinghan Ye, Zhiqiang Hu
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Patent number: 11009615Abstract: A time of flight (TOF) positron emission tomography (PET) image (38) is generated from TOF PET imaging data (10) acquired of a subject using a TOF PET imaging data acquisition device (6). Iterative image reconstruction (30) of the TOF PET imaging data is performed with TOF localization of counts along respective lines of response (LORs) to iteratively update a reconstructed image (32). Values for at least one regularization or filtering parameter are assigned to the TOF PET imaging data or to voxels of the reconstructed image based on an estimated TOF localization resolution for the TOF PET imaging data or voxels. Regularization (34) or filtering (36) of the reconstructed image is performed using the assigned values for the at least one regularization or filtering parameter. In some embodiments, the varying TOF localization resolution for the TOF PET imaging data or voxels is estimated based on related acquisition characteristics such as count rates or operating temperature of the detectors.Type: GrantFiled: December 18, 2017Date of Patent: May 18, 2021Assignee: KONINKLIJKE PHILIPS N.V.Inventors: Chuanyong Bai, Andriy Andreyev, Andre Frank Salomon, Andreas Goedicke, Jinghan Ye, Yu-Lung Hsieh, Bin Zhang, Xiyun Song, Manoj Narayanan, Zhiqiang Hu
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Patent number: 10993103Abstract: In positron emission tomography (PET) imaging, PET imaging data (22) having TOF localization is reconstructed. TOF image reconstruction (30) is performed on the PET imaging data to produce a TOF reconstructed image (32). The TOF image reconstruction utilizes the TOF localization of the PET imaging data. Non-TOF image reconstruction (40) is also performed on the PET imaging data to produce a non-TOF reconstructed image (42). The non-TOF image reconstruction does not utilize the TOF localization of the PET imaging data. A comparison image (50) is computed which is indicative of differences between the TOF reconstructed image and the non TOF reconstructed image. An adjustment (54) is determined for the TOF image reconstruction based on the comparison image, such as alignment correction of an attenuation map (18), and the TOF image reconstruction is repeated on the PET imaging data with the determined adjustment to produce an adjusted TOF reconstructed image.Type: GrantFiled: January 2, 2018Date of Patent: April 27, 2021Assignee: KONINKLIJKE PHILIPS N.V.Inventors: Chuanyong Bai, Andriy Andreyev, Bin Zhang, Xiyun Song, Jinghan Ye, Zhiqiang Hu
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Outside-FOV activity estimation using surview and prior patient data in positron emission tomography
Patent number: 10925554Abstract: A radioemission scanner (12) is operated to acquire tomographic radioemission data of a radiopharmaceutical in a subject in an imaging field of view (FOV). An imaging system is operated to acquire extension imaging data of the subject in an extended FOV disposed outside of and adjacent the imaging FOV along an axial direction (18). A distribution of the radiopharmaceutical in the subject in the extended FOV is estimated based on the extension imaging data, and further based on a database (32) of reference subjects. The tomographic radioemission data are reconstructed to generate a reconstructed image (26) of the subject in the imaging FOV. The reconstruction includes correcting the reconstructed image for scatter from the extended FOV into the imaging FOV based on the estimated distribution of the radiopharmaceutical in the subject in the extended FOV.Type: GrantFiled: December 3, 2015Date of Patent: February 23, 2021Assignee: KONINKLIJKE PHILIPS N.V.Inventors: Andriy Andreyev, Manoj Narayanan, Bin Zhang, Zhiqiang Hu, Yu-Lung Hsieh, Xiyun Song, Jinghan Ye -
Publication number: 20210030387Abstract: A non-transitory storage medium storing instructions readable and executable by an imaging workstation (18) including at least one electronic processor (20) to perform an image reconstruction method (100). The method includes: receiving emission imaging data (22) from an image acquisition device (12) wherein the emission imaging data has been filtered using an acquisition energy passband (18); generating filtered imaging data by filtering the emission imaging data with a second energy passband (90) that is narrower than an acquisition energy passband; reconstructing the filtered imaging data to generate an intermediate image; estimating one or more scatter correction factors (SCFs) from the intermediate image; and reconstructing the emission imaging data corrected with the estimated SCFs to generate a reconstructed image.Type: ApplicationFiled: August 30, 2018Publication date: February 4, 2021Applicant: Koninklijke Philips N.V.Inventors: Andriy ANDREYEV, Xiyun SONG, Jinghan YE, Chuanyong BAI, Zhiqiang HU, Douglas B. MCKNIGHT
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Patent number: 10852448Abstract: A PET detector array (8) comprising detector pixels acquires PET detection counts along lines of response (LORs). The counts are reconstructed to generate a reconstructed PET image (36, 46). The reconstructing is corrected for missing LORs which are missing due to dead detector pixels of the PET detector array. The correction may be by estimating counts along the missing LORs (60) by interpolating counts along LORs (66) neighboring the missing LORs. The interpolation may be iterative to handle contiguous groups of missing detector pixels. The correction may be by computing a sensitivity matrix having matrix elements corresponding to image elements (80, 82) of the reconstructed PET image. In this case, each matrix element is computed as a summation over all LORs intersecting the corresponding image element excepting the missing LORs. The computed sensitivity matrix is used in the reconstructing.Type: GrantFiled: December 6, 2017Date of Patent: December 1, 2020Assignee: KONINKLIJKE PHILIPS N.V.Inventors: Xiyun Song, Chuanyong Bai, Andriy Andreyev, Bin Zhang, Shushen Lin, Jinghan Ye, Michael Allen Miller, Zhiqiang Hu
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Publication number: 20200363542Abstract: A non-transitory computer-readable medium stores instructions readable and executable by a workstation (18) including at least one electronic processor (20) to perform an image reconstruction method (100) to reconstruct list mode data acquired over a frame acquisition time using a plurality of radiation detectors (17) in which the events of the list mode data is time stamped.Type: ApplicationFiled: January 30, 2019Publication date: November 19, 2020Inventors: Xiyun SONG, Chuanyong BAI, Jinghan YE, Andriy ANDREYEV, Zhiqiang HU
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Publication number: 20200334870Abstract: A non-transitory computer-readable medium stores instructions readable and executable by a workstation (18) including at least one electronic processor (20) to perform an image reconstruction method (100). The method includes: determining a weighting parameter (13) of an edge-preserving regularization or penalty of a regularized image reconstruction of an image acquisition device (12) for an imaging data set obtained by the image acquisition device; determining an edge sensitivity parameter (?) of the edge-preserving algorithm for the imaging data set obtained by the image acquisition device; and reconstructing the imaging data set obtained by the image acquisition device to generate a reconstructed image by applying the regularized image reconstruction including the edge-preserving regularization or penalty with the determined weighting and edge sensitivity parameters to the imaging data set obtained by the image acquisition device.Type: ApplicationFiled: January 2, 2019Publication date: October 22, 2020Inventors: Chuanyong BAI, Andriy ANDREYEV, Bin ZHANG, James GURIAN, Zhiqiang HU, Yu-Lung HSIEH, Shekhar DWIVEDI, Jinghan YE, Xiyun SONG, Michael Allen MILLER
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Publication number: 20200301032Abstract: A non-transitory computer-readable medium storing instructions readable and executable by a workstation (18) including at least one electronic processor (20) to perform a quality control (QC) method (100). The method includes: receiving a current QC data set acquired by a pixelated detector (14) and one or more prior QC data sets acquired by the pixelated detector; determining stability levels of detector pixels (16) of the pixelated detector over time from the current QC data set and the one or more prior QC data sets; labeling a detector pixel of the pixelated detector as dead when the stability level determined for the detector pixel is outside of a stability threshold range; and displaying, on a display device (24) operatively connected with the workstation, an identification (28) of the detector pixels labelled as dead.Type: ApplicationFiled: September 12, 2018Publication date: September 24, 2020Inventors: CHUANYONG BAI, ANDRIY ANDREYEV, SHUSHEN LIN, BIN ZHANG, MICHAEL ALLEN MILLER, XIYUN SONG, JINGHAN YE, DWIVEDI SHEKHAR, ZHIQIANG HU, YU-LUNG HSIEH, ILYA BRODSKIY, THOMAS CHRISTOPHER BULGRIN, YANG-MING ZHU, DOUGLAS B. MCKNIGHT