Abstract: Methods for purifying and isolating extracellular vesicles (EVs) from a biofluid using a sequential processing. Tangential flow filtration is applied to the biofluid to increase the concentration of EVs in the biofluid. After this is achieved, enrichment mode is halted and the biofluid is processed in diafiltration mode to remove contaminants (up to 99.9%). After performing the tangential flow filtration step, the concentration of EVs in the biofluid is further increased by ultracentrifugal filtration. After performing the ultracentrifugal filtration step, EVs of a particular target type are separated from other EVs by immunomagnetic affinity separation. In some implementations, the methods are used to isolate and quantify tumor EVs for cancer evaluation. Additionally, these methods can be used with a scaling factor to quantify EVs from a less concentrated biofluid such as, for example, urine.

Abstract: The pixel driving circuit includes a current control circuit and a gating circuit. The current control circuit is configured to transmit a driving current signal to an element to be driven. The gating circuit is configured to transmit a second voltage signal from a second voltage signal terminal to the element to be driven such that the element to be driven continuously emits light or transmit a third voltage signal from a third voltage signal terminal to the element to be driven such that the element to be driven intermittently emits light, under the control of a scan signal from a scan signal terminal, a reset signal from a reset signal terminal and a second data signal from a second data signal terminal.

Abstract: A BLUETOOTH connection method includes an electronic device establishing basic rate (BR)/enhanced data rate (EDR) connection to an accessory device. The electronic device determines that the electronic device supports a dual-mode connection and that the accessory device also supports the dual-mode connection. The dual-mode connection includes the BR/EDR connection and a BLUETOOTH Low Energy (BLE) connection. The electronic device disconnects the BR/EDR connection to the accessory device, and establishes the BLE connection to the accessory device.

Abstract: Disclosed are a pharmaceutical composition and an application thereof. The pharmaceutical composition of the present invention comprises the following components in parts by weight: 2-20 parts of phenolic acids, 0.5-5 parts of flavonoids, 0.005-0.5 part of tanshinones, 5-20 parts of saponins, and 10-18 parts of volatile oils. The pharmaceutical composition has the functions of protecting against myocardial damage and treating heart failure.

Abstract: This application relates to the field of short-range wireless communication technologies, and discloses a Bluetooth pairing method. The method includes: when a terminal receives a first operation of a user, the terminal sends an inquiry request to a Bluetooth device, where the inquiry request is used to obtain a Bluetooth address of the Bluetooth device. When receiving the inquiry request, the Bluetooth device sends an inquiry response to the terminal, where the inquiry response includes the Bluetooth address of the Bluetooth device. The Bluetooth device sends an extended inquiry response to the terminal, where the extended inquiry response includes a device name of the Bluetooth device. After receiving the extended inquiry response, the terminal displays the device name of the Bluetooth device. In this way, the terminal can reduce a time consumed by the terminal in a process from discovering the Bluetooth device to pairing with the Bluetooth device.

Abstract: Control plane management based on physical topology of nodes in software-defined networks (SDNs) is provided. Nodes in an SDN are organized into a plurality of node clusters. A cluster of nodes in an SDN is formed and control plane management for the nodes within the cluster is provided. A topology-aware assignment of nodes to controllers in an SDN is provided. Related nodes such as root and corresponding child nodes are assigned to a single cluster in one embodiment to lessen the impacts of controller failure. The assignment of nodes to controllers is also provided based on minimizing traffic between node clusters and between nodes and external networks.

Abstract: A telecommunications edge cloud (TEC) element comprising a plurality of TEC hardware components comprising a computing component that includes one or more processors, a storage component that includes a memory, a networking component, with the TEC device being deployed between a client and a packet network, the computing component being configured to manage a computing resource in the computing component, a networking resource in the networking component, and a storage resource in the storage component, allocate the computing resource for a first application of the plurality of different applications, execute the first application using the computing resource, allocate the networking resource for a second application of the plurality of different applications, execute the second application using the networking resource, allocate the storage resource for a third application of the plurality of different applications, execute the third application using the storage resource.

Abstract: The pixel driving circuit includes a current control sub-circuit configured to output a gray scale current signal to an element to be driven, and a gating sub-circuit. The gating sub-circuit is coupled to a scan signal terminal, a reset signal terminal, a gating data signal terminal and a pulse voltage signal terminal; the gating sub-circuit is configured to drive the element to be driven to continuously emit light under the control of a scan signal from the scan signal terminal and a gating data signal from the gating data signal terminal, and to drive the element to be driven to intermittently emit light under the control of a reset signal from the reset signal terminal, the gating data signal from the gating data signal terminal, and a pulse voltage signal from the pulse voltage signal terminal.

Abstract: The pixel driving circuit includes a current control circuit and a gating circuit. The current control circuit is configured to transmit a driving current signal to an element to be driven. The gating circuit is configured to transmit a second voltage signal from a second voltage signal terminal to the element to be driven such that the element to be driven continuously emits light or transmit a third voltage signal from a third voltage signal terminal to the element to be driven such that the element to be driven intermittently emits light, under the control of a scan signal from a scan signal terminal, a reset signal from a reset signal terminal and a second data signal from a second data signal terminal.

Abstract: Provided is a method and a network apparatus in a cloud infrastructure. The network apparatus includes a processor, and a memory coupled to the processor, the memory for storing computer instructions that, when executed by the processor, cause the processor to generate a resource abstraction layer relating a network cluster including a first server architecture with a first resource set and a second server architecture with a second resource set, to generate an orchestration layer configured to receive a packet flow request and, in response to the packet flow request, schedule virtual network resources based on the resource abstraction layer for servicing a packet flow, and to deploy the virtual network resources to receive and service the packet flow.

Abstract: An energy management method for a hybrid electric vehicle (HEV) includes: acquiring a state variable of an HEV; determining a speed of the HEV at a next moment by using a Markov model; according to a speed at a current moment and an acceleration at the current moment so that determining required power of the HEV at the next moment; determining battery power of the HEV according to the required power of the HEV at the next moment and engine power so that constructing a dynamic model for battery charging/discharging; determining energy costs of the HEV according to the required power at the next moment; constructing an energy optimization scheduling model of the HEV according to the energy costs; and determining an energy management model of the HEV according to the energy optimization scheduling model and the dynamic model for battery charging/discharging, to precisely manage energy of the HEV.

Abstract: Provided is a method including determining a combined plurality of accounts, determining, for each account of the combined plurality of accounts, aggregate transaction data associated with a plurality of transactions involving the account; determining a first cohort level group including a group of exposed accounts and controls accounts; determining a first segment level group of accounts from the first cohort level group of accounts; generating a prediction model based on a plurality of control accounts that are included in the first segment level group of accounts; identifying a first exposed account of a plurality of exposed accounts; determining a first control account of the plurality of control accounts that corresponds to a first exposed account using the prediction model; and outputting a report comprising data associated with the first control account that corresponds to the first exposed account. Systems and computer program products are also provided.

Abstract: The present disclosure discloses a Streptomyces antioxidans strain Sa-21, namely, strain Sa-21 with an accession number of CCTCC NO: M 2020423. The present disclosure also discloses the use of the aforementioned Strepiomyces antioxidans strain Sa-21 in inhibition of Alternaria solani (A. solani). The Streptomyces antioxidans strain also has an inhibiting effect on both plant pathogenic fungi and plant pathogenic bacteria.

Abstract: Provided is a method including determining a combined plurality of accounts, determining, for each account of the combined plurality of accounts, aggregate transaction data associated with a plurality of transactions involving the account; determining a first cohort level group including a group of exposed accounts and controls accounts; determining a first segment level group of accounts from the first cohort level group of accounts; generating a prediction model based on a plurality of control accounts that are included in the first segment level group of accounts; identifying a first exposed account of a plurality of exposed accounts; determining a first control account of the plurality of control accounts that corresponds to a first exposed account using the prediction model; and outputting a report comprising data associated with the first control account that corresponds to the first exposed account. Systems and computer program products are also provided.

Abstract: The present invention provides a redox flow battery comprising a negative electrode (also referred to herein as an “anode”) immersed in a first liquid electrolyte (also referred to herein as a “negative electrolyte” or “anolyte”), a positive electrode (also referred to herein as a “cathode”) immersed in a second liquid electrolyte (also referred to herein as a “positive electrolyte” or “catholyte”), and a cation-permeable separator (e.g., a membrane or other cation-permeable material) partitioning the negative electrode/anolyte from the positive electrode/catholyte. The redox reactant of the catholyte comprises a compound of Formula (I) as described herein.

Abstract: The present invention discloses a separator, including a top plate, a bottom plate, and a plurality of grid bars, wherein both the top plate and the bottom plate are circular in shape, and the diameter of the top plate is less than that of the bottom plate; the separator has a motor connection portion, and a center of the motor connection portion coincides with a rotation center of the separator; and the plurality of grid bars are circumferentially spaced between the top plate and the bottom plate. The present invention further discloses a cleaner with the above separator. The separator has large air inhaling force, and makes a drastic change to a speed of inhaled garbage. When the initial speed of the separator is low, it is not easy to inhale garbage. This improves a garbage separation effect without affecting the service life of a filter element.

Abstract: A method includes: adjusting, by a base station based on a timing adjustment amount, an access timing advance corresponding to user equipment to obtain a target timing advance, where the access timing advance is a timing advance obtained when the user equipment randomly accesses the base station; determining, by the base station based on the target timing advance, whether the user equipment meets a trigger condition; and if the user equipment meets the trigger condition, sending, by the base station, a trigger signal to the user equipment, where the trigger signal is used to trigger the user equipment to send a first random access request to the base station.

Abstract: A method for controlling release amount of detergent and a washing device, include: dividing inner space of a detergent box into independent N compartments, wherein each of the compartments is configured to store a type of detergent having a certain concentration range; assigning a concentration level Ci, i=1, . . . , N to each of the compartments wherein the higher the detergent concentration, the lower the concentration level; selecting one of the compartments containing detergent and releasing the detergent in the selected compartment, and obtaining the concentration level C of the selected compartment; obtaining a laundry weight m; and calculating a release amount of the detergent, wherein Vn=1.25*m*(C+1). The formula which is configured to calculate the release amount of detergent is also provided based on both of the detergent concentration level and the laundry weight.

Abstract: The present disclosure provides a method and a device for obtaining an answer, and a computer device. The method includes: receiving a question entered by a user; obtaining one or more first key information points in the question entered by the user according one or more preset word slots; asking the user about core question points through dialogue according to the one or more first key information points; obtaining answers entered by the user for the core question points; obtaining one or more second key information points in the answers entered by the user according to the one or more preset word slots; performing a retrieving in a question and answer library according to the one or more first key information points and the one or more second key information points to obtain an answer to the question entered by the user; and presenting the answer obtained to the user.

Abstract: The invention discloses an inverted cone separation device with double dust-collecting cups and cleaner comprising the same, the inverted cone separation device comprises a separator, a dust-collecting cup connecting member, and dust-collecting cups, the separator includes a first and second separator, the first separator is arranged in a first cavity, and the second separator is arranged in a second cavity; the first separator includes an inverted cone filter, the surface of the inverted cone filter includes a filtering and non-filtering surface; the filtering surface is in communication with an air duct. When implementing the invention, large-particle garbage can be separated in a first dust-collecting cup through the inverted cone filter, and other garbage enters the second dust-collecting cup through the air duct, therefore, the large-particle garbage can be separated and be effectively prevented from entangling and blocking in the dust-collecting cup, and the efficiency of dust collection is improved.