Abstract: A dissolvable frac plug adapter includes an adapter body and a temperature acquisition and recording apparatus, where the temperature acquisition and recording apparatus is fixed in the adapter body. The adapter body is configured to connect a setting tool and a dissolvable frac plug. The temperature acquisition and recording apparatus is configured to acquire and record an ambient temperature at which the adapter body is located. A method for measuring a dynamic downhole temperature using the dissolvable frac plug adapter and a method for fabricating a dissolvable frac plug using the dissolvable frac plug adapter are provided to measure the dynamic downhole ambient temperature during pumping of the dissolvable frac plug, which features convenient operation and low cost, provides a basis for material selection and design of an ideal dissolvable frac plug for a region, and facilitates fabrication of the ideal dissolvable frac plug for the region.

Abstract: A dissolvable frac plug adapter includes an adapter body and a temperature acquisition and recording apparatus, where the temperature acquisition and recording apparatus is fixed in the adapter body. The adapter body is configured to connect a setting tool and a dissolvable frac plug. The temperature acquisition and recording apparatus is configured to acquire and record an ambient temperature at which the adapter body is located. A method for measuring a dynamic downhole temperature using the dissolvable frac plug adapter and a method for fabricating a dissolvable frac plug using the dissolvable frac plug adapter are provided to measure the dynamic downhole ambient temperature during pumping of the dissolvable frac plug, which features convenient operation and low cost, provides a basis for material selection and design of an ideal dissolvable frac plug for a region, and facilitates fabrication of the ideal dissolvable frac plug for the region.

Abstract: The invention discloses a method for screening a therapeutic target of acute radiation-induced gastrointestinal syndrome and use of TIGAR target in the preparation of a medicine for treating radiation-induced gastrointestinal syndrome. The CreERT-loxP transgenic mouse model is used, in which quiescent intestinal crypt stem cells are effectively promoted to proliferate after exposure to high-dose ionizing radiation, to screen a therapeutic target that still has a therapeutic effect for radiation-induced gastrointestinal syndrome 18-24 h after ionizing radiation. Gene splicing occurs in particular cells in the CreERT-loxP transgenic mice only after the injection of tamoxifen, thereby regulating gene expression. The actual situation of initial exposure and then treatment after a nuclear accident is well simulated, so the invention is of great practical significance.