Patents by Inventor Jinny Lin Liu

Jinny Lin Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230050657
    Abstract: Described herein are single-domain antibodies that might serve as alternatives to conventional monoclonal antibodies for either the detection or treatment of Venezuelan equine encephalitis virus (VEEV).
    Type: Application
    Filed: June 29, 2022
    Publication date: February 16, 2023
    Inventors: Jinny Lin Liu, Dan Zabetakis, Ellen R. Goldman, George P. Anderson
  • Patent number: 11542320
    Abstract: Described herein are nucleic acids encoding single-domain antibodies that might serve as alternatives to conventional monoclonal antibodies for either the detection or treatment of Chikungunya Virus (CHIKV).
    Type: Grant
    Filed: July 9, 2021
    Date of Patent: January 3, 2023
    Assignee: The Government of the United States of Americas, as represented by the Secretary of the Navy
    Inventors: Jinny Lin Liu, George P. Anderson, Ellen R. Goldman
  • Publication number: 20210347863
    Abstract: Described herein are nucleic acids encoding single-domain antibodies that might serve as alternatives to conventional monoclonal antibodies for either the detection or treatment of Chikungunya Virus (CHIKV).
    Type: Application
    Filed: July 9, 2021
    Publication date: November 11, 2021
    Inventors: Jinny Lin Liu, George P. Anderson, Ellen R. Goldman
  • Patent number: 11028152
    Abstract: Described herein are single-domain antibodies that might serve as alternatives to conventional monoclonal antibodies for either the detection or treatment of Chikungunya Virus (CHIKV).
    Type: Grant
    Filed: July 17, 2019
    Date of Patent: June 8, 2021
    Assignee: The Government of the United States of America, as represented by the Secretary of the Navy
    Inventors: Jinny Lin Liu, George P. Anderson, Ellen R. Goldman
  • Publication number: 20200240982
    Abstract: Expression of single-domain antibodies with a C-terminal binding partner (such as SpyTag) enables their orientation on surfaces, improving detection capability.
    Type: Application
    Filed: January 17, 2020
    Publication date: July 30, 2020
    Inventors: George P. Anderson, Jinny Lin Liu, Ellen R. Goldman
  • Publication number: 20200024331
    Abstract: Described herein are single-domain antibodies that might serve as alternatives to conventional monoclonal antibodies for either the detection or treatment of Chikungunya Virus (CHIKV).
    Type: Application
    Filed: July 17, 2019
    Publication date: January 23, 2020
    Inventors: Jinny Lin Liu, George P. Anderson, Ellen R. Goldman
  • Patent number: 10246514
    Abstract: Described herein is the development of recombinant single domain antibodies, also known as nanobodies, that may provide better therapeutic results or be useful for diagnostic applications of B-cell lymphomas, or in other applications where an antibody to CD20 may be useful.
    Type: Grant
    Filed: September 12, 2017
    Date of Patent: April 2, 2019
    Assignee: The United States of America, as represented by the Secretary of the Navy
    Inventors: Jinny Lin Liu, Daniel Zabetakis, Ellen R. Goldman, George P. Anderson
  • Patent number: 10247716
    Abstract: Described herein are new recognition elements (antibodies or functional fragments thereof) that effectively bind to trinitrotoluene (TNT). Also disclosed is a single chain fragment recognition element.
    Type: Grant
    Filed: January 6, 2016
    Date of Patent: April 2, 2019
    Assignee: The United States of America, as represented by the Secretary of the Navy
    Inventors: Jinny Lin Liu, Daniel Zabetakis, Ellen R. Goldman, George P. Anderson
  • Publication number: 20180079822
    Abstract: Described herein is the development of recombinant single domain antibodies, also known as nanobodies, that may provide better therapeutic results or be useful for diagnostic applications of B-cell lymphomas, or in other applications where an antibody to CD20 may be useful.
    Type: Application
    Filed: September 12, 2017
    Publication date: March 22, 2018
    Inventors: Jinny Lin Liu, Daniel Zabetakis, Ellen R. Goldman, George P. Anderson
  • Patent number: 9778265
    Abstract: Genetic fusions of proteins, for example single-domain antibodies (sdAbs), with a positively-charged domain enhanced immobilization of active protein in a desired orientation.
    Type: Grant
    Filed: April 16, 2015
    Date of Patent: October 3, 2017
    Assignee: The United States of America, as represented by the Secretary of the Navy
    Inventors: George P. Anderson, Jinny Lin Liu, Marc P. Raphael, Ellen R. Goldman
  • Publication number: 20160305948
    Abstract: Genetic fusions of proteins, for example single-domain antibodies (sdAbs), with a positively-charged domain enhanced immobilization of active protein in a desired orientation.
    Type: Application
    Filed: April 16, 2015
    Publication date: October 20, 2016
    Applicant: The Govemment of The US, as represented by the Secretary of the Navy
    Inventors: George P. Anderson, Jinny Lin Liu, Marc P. Raphael, Ellen R. Goldman
  • Publication number: 20160200834
    Abstract: Described herein are new recognition elements (antibodies or functional fragments thereof) that effectively bind to trinitrotoluene (TNT). Also disclosed is a single chain fragment recognition element.
    Type: Application
    Filed: January 6, 2016
    Publication date: July 14, 2016
    Inventors: Jinny Lin Liu, Daniel Zabetakis, Ellen R. Goldman, George P. Anderson
  • Patent number: 9267930
    Abstract: Described herein are new recognition elements (antibodies or functional fragments thereof) that effectively bind to trinitrotoluene (TNT). Also disclosed is a single chain fragment recognition element.
    Type: Grant
    Filed: October 17, 2012
    Date of Patent: February 23, 2016
    Assignee: The United States of America, as represented by the Secretary of the Navy
    Inventors: Jinny Lin Liu, Daniel Zabetakis, Ellen R. Goldman, George P. Anderson
  • Publication number: 20150268214
    Abstract: Described herein are new recognition elements (antibodies or functional fragments thereof) that effectively bind to trinitrotoluene (TNT). Also disclosed is a single chain fragment recognition element.
    Type: Application
    Filed: October 17, 2012
    Publication date: September 24, 2015
    Inventors: Jinny Lin Liu, Daniel Zabetakis, Ellen R. Goldman, George P. Anderson
  • Patent number: 8831386
    Abstract: Protein scaffolds from tobacco mosaic virus coat protein modified to incorporate polyhistidine can bind to a metal or a dye while having improved self-assembly characteristics. The scaffold can take the form of tubes or disks, and can further be formed into dual plasmonic ring resonators. Such self-assembled structures provide useful optical properties.
    Type: Grant
    Filed: January 12, 2012
    Date of Patent: September 9, 2014
    Assignee: The United States of America, as represented by the Secretary of the Navy
    Inventors: Banahalli R. Ratna, Amy S. Blum, Carissa M. Soto, Michael A. Bruckman, Jinny Lin Liu, Ronald W. Rendell, James Peter Long, Ronald J. Tonucci
  • Publication number: 20130181171
    Abstract: Protein scaffolds from tobacco mosaic virus coat protein modified to incorporate polyhistidine can bind to a metal or a dye while having improved self-assembly characteristics. The scaffold can take the form of tubes or disks, and can further be formed into dual plasmonic ring resonators. Such self-assembled structures provide useful optical properties.
    Type: Application
    Filed: January 12, 2012
    Publication date: July 18, 2013
    Inventors: Banahalli R. Ratna, Amy S. Blum, Carissa M. Soto, Michael A. Bruckman, Jinny Lin Liu, Ronald W. Rendell, James Peter Long, Ronald J. Tonucci
  • Publication number: 20120214867
    Abstract: A T4 nanoparticle is a non-infectious, tail-less variant of a T4 bacteriophage. In one embodiment, eukaryotic cells are labeled with dyed T4 nanoparticles, wherein each dyed T4 nanoparticle comprises at least 350 dye molecules covalently bound thereto. In another embodiment, T4 nanoparticles are used to deliver exogenous DNA to eukaryotic cells for protein expression therein. It is contemplated that T4 nanoparticles may be used to deliver other exogenous material to eukaryotic cells.
    Type: Application
    Filed: February 14, 2012
    Publication date: August 23, 2012
    Applicant: The Government of the United States of America, as represented by the Secretary of the Navy
    Inventors: Jinny Lin Liu, Kelly L. Robertson, Carissa M. Soto
  • Publication number: 20110183856
    Abstract: The present invention provides a specific set of gene expression markers from peripheral blood leukocytes that are indicative of a host response to exposure, response, and recovery infectious pathogen infections. The present invention further provides methods for identifying the specific set of gene expression markers, methods of monitoring disease progression and treatment of infectious pathogen infections, methods of prognosing the onset of an infectious pathogen infection, and methods of diagnosing an infectious pathogen infection and identifying the pathogen involved.
    Type: Application
    Filed: February 26, 2010
    Publication date: July 28, 2011
    Applicants: The Government of the United States of America, as represented by the Secretary of the Navy
    Inventors: Brian K. Agan, Eric H. Hanson, Michael J. Jenkins, Baochuan Lin, Chris C. Olsen, Robb K. Rowley, David A. Stenger, Dzung C. Thach, Clark J. Tibbetts, Elizabeth A. Walter, Jinny Lin Liu
  • Patent number: 7947626
    Abstract: This invention comprises a method for generating functional neural networks using neural progenitor cells on microelectrode arrays (MEAs). The method involves dissociating neural progenitor cells from an embryo, propagating the neural progenitor cells, passaging the neural progenitor cells and seeding the neural progenitor cells on MEAs to produce a functional neural network. The neural progenitor cells may be continuously passaged to propagate an endless supply of neural progenitor cells. The resultant passaged progenitor cell derived neural network MEA may be used to detect and/or quantify various biological or chemical toxins.
    Type: Grant
    Filed: August 29, 2007
    Date of Patent: May 24, 2011
    Assignee: The United States of America as represented by the Secretary of the Navy
    Inventors: Wu Ma, Jinny Lin Liu, Thomas O'Shaughnessy