Abstract: A method for preparing a polyglutamic acid (?-PGA) fiber having antibacterial and water absorption properties is provided. The method includes providing a ?-PGA fiber and immersing it in a sodium hypochlorite solution. A relation exists between an immersing time T of the ?-PGA fiber and a concentration X of the sodium hypochlorite solution as shown in the formula below: 10.2?(T?64.55X2+50X)?15.2, wherein X is 0.006-0.4 wt %.

Abstract: A water-insoluble polyglutamic acid (PGA) fiber and a preparation method thereof are provided. In the preparation method, the PGA is cross-linked by a cross-linking agent and then passes through a spinning nozzle to form PGA fibers. Therefore, the highly water-absorbing PGA, which cannot be spun by conventional methods, can be spun to form PGA fibers and maintain the high water-absorption ability.

Abstract: A multi-layer antimicrobial wound dressing includes a wound-contacting layer and an antimicrobial layer. The wound contacting layer includes a biocompatible fibrous matrix that is made of an anionic polymer, and the antimicrobial layer is made of a cationic polymer that is connected to the wound-contacting layer via anionic-cationic interaction between the anionic polymer of the fibrous matrix and the cationic polymer of the antimicrobial layer.

Abstract: A biocompatible implant composite particle and the method of making the same are provided. The implant composite particle includes a bone filler particle and a plurality of fibers, in which each fiber is partially embedded in the bone filler particle, and has a free portion extending from a surface of the bone filler particle. Both bone filler particle and fibers are biocompatible. The biocompatible implant composite can be used in a bone filler material for bone defects.

Abstract: A water-insoluble polyglutamic acid (PGA) fiber and a preparation method thereof are provided. In the preparation method, the PGA is cross-linked by a cross-linking agent and then passes through a spinning nozzle to form PGA fibers. Therefore, the highly water-absorbing PGA, which cannot be spun by conventional methods, can be spun to form PGA fibers and maintain the high water-absorption ability.

Abstract: A polyglutamic acid (?-PGA) fiber having antibacterial property and high water absorptivity is provided. A main component of the ?-PGA fiber includes a modified ?-PGA, and the modified ?-PGA is a polymer consisting of a ?-glutamic acid segment and a ?-modified glutamic acid segment, in which the modified glutamic acid segment has a formula as shown below: wherein X is H or Na, and Y is Cl, Br or I, and wherein a molar ratio of the modified ?-glutamic acid segment to the ?-glutamic acid segment is not lower than 0.05.

Abstract: A method for preparing a polyglutamic acid (?-PGA) fiber having antibacterial and water absorption properties is provided. The method includes providing a ?-PGA fiber and immersing it in a sodium hypochlorite solution. A relation exists between an immersing time T of the ?-PGA fiber and a concentration X of the sodium hypochlorite solution as shown in the formula below: 10.2?(T?64.55X2+50X)?15.2, wherein X is 0.006-0.4 wt %.

Abstract: The present invention provides a porous bone cement containing a powder mixture and an aqueous solution, in which the aqueous solution is water or an inorganic salt solution and the powder mixture contains: (a) two or more bone substitution materials having different average particle sizes and independently selected from the group consisting of calcium phosphate salts, polymers and metals or salts thereof, provided that at least one of the bone substitution materials is calcium phosphate salts; (b) calcium sulfate; and (c) a bioresorbable molecule which is soluble in the aqueous solution and has higher biological resorption or degradation rate than calcium sulfate. The porous bone cement of the present invention is applicable in treating dental and bone defects and in plastic surgery.

Abstract: A water-insoluble polyglutamic acid (PGA) fiber and a preparation method thereof are provided. In the preparation method, the PGA is cross-linked by a cross-linking agent and then passes through a spinning nozzle to form PGA fibers. Therefore, the highly water-absorbing PGA, which cannot be spun by conventional methods, can be spun to form PGA fibers and maintain the high water-absorption ability.