Patents by Inventor Joachim Lingner

Joachim Lingner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Human telomerase catalytic subunit: diagnostic and therapeutic methods
    Patent number: 6475789
    Abstract: The invention provides compositions and methods related to human telomerase reverse transcriptase (hTRT), the catalytic protein subunit of human telomerase. The polynucleotides and polypeptides of the invention are useful for diagnosis, prognosis, and treatment of human diseases, for changing the proliferative capacity of cells and organisms, and for identification and screening of compounds and treatments useful for treatment of diseases such as cancers.
    Type: Grant
    Filed: August 14, 1997
    Date of Patent: November 5, 2002
    Assignees: University Technology Corporation, Geron Corporation
    Inventors: Thomas R. Cech, Joachim Lingner, Toru Nakamura, Karen B. Chapman, Gregg B. Morin, Calvin B. Harley, William H. Andrews
  • Antisense compositions for detecting and inhibiting telomerase reverse transcriptase
    Patent number: 6444650
    Abstract: The present invention provides TRT antisense oligonucleotides, methods of detecting TRT, methods of diagnosing telomerase-related conditions, methods of diagnosing and providing a prognosis for cancer, and methods of treating telomerase-related conditions, including cancer.
    Type: Grant
    Filed: March 31, 1998
    Date of Patent: September 3, 2002
    Assignees: Geron Corporation, University Technology Corporation
    Inventors: Thomas R. Cech, Joachim Lingner, Toru Nakamura, Karen B. Chapman, Gregg B. Morin, Calvin B. Harley, William H. Andrews
  • Telomerase
    Patent number: 6261836
    Abstract: The present invention is directed to telomerase nucleic acids and amino acids. In particular, the present invention is directed to nucleic acid and amino acid sequences encoding various telomerase protein subunits and motifs, including the 123 kDa and 43 kDa telomerase protein subunits of Euplotes aediculatus, and related sequences from Schizosaccharomyces, Saccharomyces sequences, and human telomerase. The present invention is also directed to polypeptides comprising these telomerase protein subunits, as well as functional polypeptides and ribonucleoproteins that contain these subunits.
    Type: Grant
    Filed: May 9, 1997
    Date of Patent: July 17, 2001
    Assignees: Geron Corporation, University Technology Corporation
    Inventors: Thomas R. Cech, Joachim Lingner, Toru Nakamura, Karen B. Chapman, Gregg B. Morin, Calvin B. Harley, William H. Andrews
  • Telomerase catalytic subunit
    Patent number: 6166178
    Abstract: The invention provides compositions and methods related to telomerase reverse transcriptase, the catalytic protein subunit of human telomerase. The polynucleotides and polypeptides of the invention are useful for diagnosis, prognosis and treatment of human diseases, for changing the proliferative capacity of cells and organisms, and for identification and screening of compounds and treatments useful for treatment of diseases such as cancers.
    Type: Grant
    Filed: November 19, 1997
    Date of Patent: December 26, 2000
    Assignees: University Technology Corporation, Geron Corporation
    Inventors: Thomas R. Cech, Joachim Lingner
  • Telomerase
    Patent number: 6093809
    Abstract: The present invention is directed to novel telomerase nucleic acids and amino acids. In particular, the present invention is directed to nucleic acid and amino acid sequences encoding various telomerase protein subunits and motifs, including the 123 kDa and 43 kDa telomerase protein subunits of Euplotes aediculatus, and related sequences from Schizosaccharomyces, Saccharomyces sequences, and human telomerase. The present invention is also directed to polypeptides comprising these telomerase protein subunits, as well as functional polypeptides and ribonucleoproteins that contain these subunits.
    Type: Grant
    Filed: May 6, 1997
    Date of Patent: July 25, 2000
    Assignees: University Technology Corporation, Geron Corporation
    Inventors: Thomas R. Cech, Joachim Lingner
  • Recombinant poly(A) polymerase
    Patent number: 5525497
    Abstract: Purified nucleic acid encoding a yeast, human, or bovine poly(A) polymerase, where the bovine nucleic acid consists essentially of that nucleic acid sequence shown as nucleotide SEQ. ID. NO.: 1; the resulting recombinant poly(A) polymerase expressed from these nucleic acids, corresponding methods of their production, and methods of use of the poly(A) polymerase.
    Type: Grant
    Filed: November 27, 1991
    Date of Patent: June 11, 1996
    Inventors: Walter Keller, Joachim Lingner, Georges Martin, Elmar Wahle