Abstract: The present invention relates to a computer-implemented method for identifying an incorrectly or non-calibrated infrared spectrometer, comprising the steps of a) recording an infrared spectrum of a sample with a first infrared spectrometer to provide a sample infrared spectrum, b) recording an infrared spectrum of the same sample as in step a) with a second infrared spectrometer to provide a reference infrared spectrum, wherein said second spectrometer is a correctly calibrated infrared spectrometer, or b?) providing a reference spectrum of the same sample as in step a), wherein said reference spectrum was recorded on a second infrared spectrometer, which is a correctly calibrated spectrometer, c) determining a difference between the wavelength of each extreme point in the sample of step a) and the wavelength of each extreme point in the reference spectrum of step b) or b?), and d) indicating the infrared spectrometer of step a) as incorrectly calibrated or non-calibrated, when at least one difference was det

Abstract: An installation assembly for a loudspeaker, in particular in a vehicle door, contains a support element having a receiving opening for the loudspeaker, a loudspeaker basket having a flange, and a sealing element in the region of a mechanical abutment interface between the loudspeaker basket and the support element. During installation, the loudspeaker extends through the receiving opening on the support side, and the flange on the basket side abuts the support element with the interposition of the sealing element. The loudspeaker basket has a number of joining elements which correspond to joining contours of the support element to produce a bayonet coupling or a push-and-turn connection.

Abstract: The present invention relates to a composition comprising a binder comprising one or more siloxane polymers, silicone resins, silicone based elastomers, and mixtures thereof, wherein said binder optionally comprises one or more cross-linker components comprising a silane and/or a siloxane containing silicon-bonded hydrolysable groups; and a hydrophilic powder and/or gel selected from one or more amorphous, porous hydrophilic silica(s),one or more hydrophilic silica aerogel (s) and mixtures thereof, said amorphous, porous hydrophilic silica and/or said hydrophilic silica aerogel having a BET surface area from 100 m2/g to 1500 m2/g or greater and a thermal conductivity from 0.004 to 0.05 W/m·K at 20° C. and atmospheric pressure. The invention also relates to the use of said composition as or in thermally or acoustically insulating materials and to coatings, products and articles made therefrom.

Abstract: The present invention relates to a composition comprising a binder comprising one or more siloxane polymers, silicone resins, silicone based elastomers, and mixtures thereof, wherein said binder optionally comprises one or more cross-linker components comprising a silane and/or a siloxane containing silicon-bonded hydrolysable groups; and a hydrophilic powder and/or gel selected from one or more amorphous, porous hydrophilic silica(s), one or more hydrophilic silica aerogel(s) and mixtures thereof, said amorphous, porous hydrophilic silica and/or said hydrophilic silica aerogel having a BET surface area from 100 m2/g to 1500 m2/g or greater and a thermal conductivity from 0.004 to 0.05 W/m·K at 20° C. and atmospheric pressure. The invention also relates to the use of said composition as or in thermally or acoustically insulating materials and to coatings, products and articles made therefrom.

Abstract: A vehicle door includes a wet space provided within the vehicle door, which is separated from a dry space on the vehicle door, wherein the vehicle door includes at least a door skin that borders the wet space and dry space, a speaker, and a resonance body component configured to form a resonance space for the speaker, wherein the resonance body component defines a closed volume for the resonance space in the wet space of the vehicle door.

Abstract: The present invention relates to the use of human anti-inflammatory peptides in the inhalatory treatment of inflammatory pulmonary diseases. The invention in particular relates to the use of vasoactive intestinal peptide, C-type natriuretic peptide, B-type natriuretic peptide, pituitary adenylate cyclase-activating peptide, adrenomedullin, alpha-melanocyte stimulating hormone, relaxin and Interferon gamma for said purposes. Advantageous features of an aerosol containing such a human anti-inflammatory peptide and a method for producing said aerosol are disclosed. The present invention further relates to a kit for inhalatory treatment of inflammatory pulmonary diseases. One aspect relates to treatment of CoViD-19 related ARDS.

Abstract: The present invention relates to a process for recovering acrylic acid which is obtained by catalytic gas phase oxidation of propene, wherein, in an absorption stage (K2), the acrylic acid is absorbed from the reaction mixture (1) from the gas phase oxidation with a first solvent (3) and is drawn off for distillative purification, and a gas mixture from the absorption stage (K2) is passed onward to a condensation stage, wherein, in the condensation stage, the gas mixture is condensed, and a condensed phase of the gas mixture is drawn off as acid water (4) and is subjected to a phase separation operation in a phase separation vessel (B1), comprising the steps of a) feeding the aqueous phase (4*) of the acid water (4) drawn off from the condensation stage that has been obtained in the phase separation vessel (B1) to an extraction stage (K7) in which acrylic acid present in the acid water (4) is extracted with a second solvent (5), b) feeding the acrylic acid-comprising extract (6) to a stripping column (K8) in

Abstract: An exhaust gas heater for an exhaust gas system of a combustion engine includes a disk-like carrier defining a heater longitudinal axis and having a first axial side. The carrier has an outer peripheral region disposed radially outwardly of the longitudinal axis and a radially inwardly disposed central region. A heating conductor has a heating region arranged on the first axial side of the carrier. At least one holding member holds the heating conductor on the carrier. The holding member includes at least one holding portion engaging around the heating conductor at the heating region thereof. The carrier has at least one fastening opening formed therein. The holding member includes at least one fastening portion engaging into the at least one fastening opening so as to be fixed to the carrier.

Abstract: A system and method for determining if a field calibration of a subject sensor associated with a vehicle is warranted, and calibrating the subject sensor using a sensor associated with another vehicle when calibration is warranted. Reference vehicles may perform predetermined maneuvers in order to provide additional measurements for use during calibration.

Abstract: A process for the continuous production of either acrolein or acrylic acid as the target product from propene comprising a catalyzed gas phase partial oxidation of propene to yield a product gas containing the target product, transferring the target product in a separating zone from the product gas into the liquid phase and conducting out of the separating zone a stream of residual gas the major portion of which is returned into the partial oxidation and the remaining portion of said stream is purged from the process as off-gas from which synthesis gas can be produced or which can be added to synthesis gas produced otherwise.

Abstract: A mixer assembly unit, especially for an exhaust system of an internal combustion engine of a vehicle, includes a mixer body (48) with an incoming flow side (58) and with an outgoing flow side (60); and a carrier element (24) with a carrier element body (44) enclosing the mixer body (48) radially on an outside in relation to a mixer longitudinal axis. The mixer body (48) includes a plurality of flow deflection elements (62) and at least one holding area (70). The carrier element (24) includes a counter holding area (46) in association with a holding area (70). The counter holding area (46) is connected in substance to the holding area (70). The counter holding area (46) overlaps the holding area (70) at least partly radially on a side oriented in a direction of the outgoing flow side (60) of the mixer body (48).

Abstract: Checkpoint inhibitor-induced pneumonitis (CIP) is characterized clinically by dyspnea, cough and tachypnea. Hypoxia results from a lymphocyte-dominated alveolitis leading to ground glass opacities and consolidations observed by CT scan. Histological findings include lymphocytic infiltrates, granuloma formation and eosinophilic accumulation. In the management of CIP, systemic administration of steroids such as methylprednisolone is the standard therapy. Moreover, CIP in most cases leads to discontinuation of checkpoint inhibitory therapy and steroids limit the therapeutic effect of checkpoint inhibitors resulting in progression of the underlying malignant disease. Therefore, there is a need of other therapeutic options in CIP that ideally could abrogate the alveolar inflammation induced by checkpoint inhibitors without affecting the systemic effect on the immune system.

Abstract: A system and method of sensor validation utilizing a sensor-fusion network. The sensor-fusion network may comprise a number of sensors associated with one or more vehicles having autonomous or partially autonomous driving functions.

Abstract: An exhaust gas heater for an exhaust gas system of a combustion engine includes a disk-like carrier defining a heater longitudinal axis and having a first axial side. The carrier has an outer peripheral region disposed radially outwardly of the longitudinal axis and a radially inwardly disposed central region. A heating conductor has a heating region arranged on the first axial side of the carrier. At least one holding member holds the heating conductor on the carrier. The holding member includes at least one holding portion engaging around the heating conductor at the heating region thereof. The carrier has at least one fastening opening formed therein. The holding member includes at least one fastening portion engaging into the at least one fastening opening so as to be fixed to the carrier.

Abstract: A pipe, especially an internal combustion engine, exhaust system, exhaust gas-guiding pipe, includes a connection area (26). The connection area (26) is at an axial pipe end (12) for connecting the pipe (14) extending in a pipe longitudinal axis (A) to another pipe (16) to be pushed into the connection area (26). The connection area (26) includes two slots (18a, 18b). The slots (18a, 18b) include a first slot area (20a, 20b), located closer to the pipe end (12), and a second slot area (22a, 22b), located axially farther away from the pipe end (12) and offset in a circumferential direction in relation to the first slot area (20a, 20b). The second slot areas (22a, 22b) of the two slots (18a, 18b) are offset toward one another or away from one another in the circumferential direction in relation to the first slot areas (20a, 20b).

Abstract: The present invention relates to an isolated soluble CCR6 receptor polypeptide capable of binding to CCL18 and/or CCL20 and to a method for quantifying the concentration of a soluble CCR6 receptor polypeptide in a liquid sample from a subject. The present invention also relates to a method for detecting and/or prognosticating an interstitial lung disease or a cancer in a subject by determining the level of a soluble CCR6 receptor polypeptide in a sample from said subject and further provides a pharmaceutical composition comprising a compound capable of inhibiting the activity and/or the expression of CCL18 or CCL20 for the treatment of said diseases. The present invention further relates to an isolated polypeptide capable of binding to and inhibiting the activity of the chemokine receptor CCR6 and to a method for identifying further inhibitors of CCR6 receptor activity.

Abstract: The present invention relates to a composition comprising a binder comprising one or more siloxane polymers, silicone resins, silicone based elastomers, and mixtures thereof, wherein said binder optionally comprises one or more cross-linker components comprising a silane and/or a siloxane containing silicon-bonded hydrolysable groups; and a hydrophilic powder and/or gel selected from one or more amorphous, porous hydrophilic silica(s), one or more hydrophilic silica aerogel(s) and mixtures thereof, said amorphous, porous hydrophilic silica and/or said hydrophilic silica aerogel having a BET surface area from 100 m2/g to 1500 m2/g or greater and a thermal conductivity from 0.004 to 0.05 W/mK at 20° C. and atmospheric pressure. The invention also relates to the use of said composition as or in thermally or acoustically insulating materials and to coatings, products and articles made therefrom.

Abstract: The present invention relates to a composition comprising a binder comprising one or more siloxane polymers, silicone resins, silicone based elastomers, and mixtures thereof, wherein said binder optionally comprises one or more cross-linker components comprising a silane and/or a siloxane containing silicon-bonded hydrolysable groups; and a hydrophilic powder and/or gel selected from one or more amorphous, porous hydrophilic silica (s) having a thermal conductivity at 20° C. and atmospheric pressure of 0.001 to 0.15 W/m·K and a surface area (SBET) of between 200 and 1500 m2/g, one or more hydrophilic aerogel (s) and mixtures thereof, wherein the binder is a solution, an emulsion, or a dispersion in water. The invention also relates to the use of the composition as or in thermally or acoustically insulating materials and to coated substrates, products and articles made by using the composition.

Abstract: The present invention relates to an isolated soluble CCR6 receptor polypeptide capable of binding to CCL18 and/or CCL20 and to a method for quantifying the concentration of a soluble CCR6 receptor polypeptide in a liquid sample from a subject. The present invention also relates to a method for detecting and/or prognosticating an interstitial lung disease or a cancer in a subject by determining the level of a soluble CCR6 receptor polypeptide in a sample from said subject and further provides a pharmaceutical composition comprising a compound capable of inhibiting the activity and/or the expression of CCL18 or CCL20 for the treatment of said diseases. The present invention further relates to an isolated polypeptide capable of binding to and inhibiting the activity of the chemokine receptor CCR6 and to a method for identifying further inhibitors of CCR6 receptor activity.

Abstract: Multimetal oxide composition comprising Mo, Bi, Fe, Cu and one or more than one of the elements Co and Ni and use thereof.