Patents by Inventor Joan Claudia Maureen Soei-Ken Tjon

Joan Claudia Maureen Soei-Ken Tjon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for providing adjuvanted virosomes and adjuvanted virosomes obtainable thereby
    Patent number: 10588963
    Abstract: The invention relates to the fields of immunology and vaccinology. Provided is a method for preparing adjuvanted virosomes, comprising the steps of: (i) providing an aqueous composition of non-adjuvanted virosomes comprising a membrane fusion protein; (ii) dissolving an amphiphilic adjuvant in a pharmaceutically acceptable non-aqueous solvent which can form a homogeneous mixture with water; and (iii) diluting said adjuvant solution in said aqueous virosome composition to induce insertion of adjuvant in the outer leaflet of the virosomal membrane while preserving membrane fusion activity of the virosomes. Also provided are adjuvanted virosomes obtainable by said method, and vaccines comprising the virosomes.
    Type: Grant
    Filed: September 12, 2014
    Date of Patent: March 17, 2020
    Assignee: BESTEWIL HOLDING B.V.
    Inventors: Antonius Johannes Henrikus Stegmann, Joan Claudia Maureen Soei-Ken Tjon
  • METHODS FOR PROVIDING ADJUVANTED VIROSOMES AND ADJUVANTED VIROSOMES OBTAINABLE THEREBY
    Publication number: 20170189523
    Abstract: The invention relates to the fields of immunology and vaccinology. Provided is a method for preparing adjuvanted virosomes, comprising the steps of: (i) providing an aqueous composition of non-adjuvanted virosomes comprising a membrane fusion protein; (ii) dissolving an amphiphilic adjuvant in a pharmaceutically acceptable non-aqueous solvent which can form a homogeneous mixture with water; and (iii) diluting said adjuvant solution in said aqueous virosome composition to induce insertion of adjuvant in the outer leaflet of the virosomal membrane while preserving membrane fusion activity of the virosomes. Also provided are adjuvanted virosomes obtainable by said method, and vaccines comprising the virosomes.
    Type: Application
    Filed: September 12, 2014
    Publication date: July 6, 2017
    Inventors: Antonius Johannes Henrikus Stegmann, Joan Claudia Maureen Soei-Ken Tjon