Patents by Inventor Joanne J. Bronson

Joanne J. Bronson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modulators of G Protein-Coupled Receptor 88
    Publication number: 20110251196
    Abstract: The present disclosure is generally directed to compounds which can modulate G-protein coupled receptor 88, compositions comprising such compounds, and methods for modulating G-protein coupled receptor 88.
    Type: Application
    Filed: October 5, 2010
    Publication date: October 13, 2011
    Inventors: Carolyn Diane Dzierba, Richard A. Hartz, Yingzhi Bi, Vijay T. Ahuja, Joanne J. Bronson, Kenneth Carson, Giovanni Cianchetta, Michael Green, David Kimball, S. Roy Kimura, Soojin Kwon, John E. Macor, Yulian Zhang, Greg Zipp
  • Modulators of G Protein-Coupled Receptor 88
    Publication number: 20110245264
    Abstract: The present disclosure is generally directed to compounds which can modulate G-protein coupled receptor 88, compositions comprising such compounds, and methods for modulating G-protein coupled receptor 88.
    Type: Application
    Filed: October 1, 2010
    Publication date: October 6, 2011
    Inventors: Yingzhi Bi, Carolyn Diane Dzierba, Joanne J. Bronson, Kenneth Carson, Giovanni Cianchetta, Li Dong, Cynthia Fink, Michael Green, David Kimball, John E. Macor, Soojin Kwon, Jiancheng Wang, Yulian Zhang, Greg Zipp
  • Substituted heterocyclic ethers and their use in CNS disorders
    Patent number: 8026257
    Abstract: The invention encompasses compounds of Formula I, including pharmaceutically acceptable salts, their pharmaceutical compositions, and their use in treating CNS disorders.
    Type: Grant
    Filed: July 1, 2008
    Date of Patent: September 27, 2011
    Assignee: Bristol-Myers Squibb Company
    Inventors: Andrew P. Degnan, George O. Tora, Derek J. Denhart, Vivekananda M. Vrudhula, John E. Macor, Joanne J. Bronson
  • Pyrazinone Modulator of Corticotropin-Releasing Factor Receptor Activity
    Publication number: 20110166160
    Abstract: The invention relates to the compound (S)-4-(1-cyclopropyl-2-methoxyethyl)-6-(6-(difluoromethoxy)-2,5-dimethylpyridin-3-ylamino)-5-oxo-4,5-dihydropyrazine-2-carbonitrile, pharmaceutical compositions of the compound, and methods of using the compound for the treatment of psychiatric disorders and neurological diseases including depression, anxiety related disorders, irritable bowel syndrome, addiction and negative aspects of drug and alcohol withdrawal, and other conditions associated with CRF.
    Type: Application
    Filed: March 21, 2011
    Publication date: July 7, 2011
    Inventors: Richard A. Hartz, Vijay T. Ahuja, Vivekananda M. Vrudhula, Joanne J. Bronson
  • Alpha-(N-Sulfonamido)Acetamide Derivatives as Beta-Amyloid Inhibitors
    Publication number: 20110105485
    Abstract: There is provided a series of novel ?-(N-sulfonamido)acetamide compounds of the Formula (I) wherein R, R1, R2 and R3 are defined herein, which are inhibitors of ?-amyloid peptide (?-AP) production and are useful in the treatment of Alzheimer's Disease and other conditions affected by anti-amyloid activity.
    Type: Application
    Filed: July 21, 2010
    Publication date: May 5, 2011
    Inventors: Michael F. Parker, Katharine E. McElhone, Robert A. Mate, Joanne J. Bronson, Yonghua Gai, Carl P. Bergstrom, Lawrence R. Marcin, John E. Macor
  • ()-4-(1-cyclopropyl-2-methoxyethyl)-6-(6-(difluoromethoxy)-2,5-dimethylpyridin-3-ylamino)-5-oxo-4,5-dihydropyrazine-2-carbonitrile: a pyrazinone modulator of corticotropin-releasing factor receptor activity
    Patent number: 7932256
    Abstract: The invention relates to the compound (S)-4-(1-cyclopropyl-2-methoxyethyl)-6-(6-(difluoromethoxy)-2,5-dimethylpyridin-3-ylamino)-5-oxo-4,5-dihydropyrazine-2-carbonitrile, pharmaceutical compositions of the compound, and methods of using the compound for the treatment of psychiatric disorders and neurological diseases including depression, anxiety related disorders, irritable bowel syndrome, addiction and negative aspects of drug and alcohol withdrawal, and other conditions associated with CRF.
    Type: Grant
    Filed: April 24, 2009
    Date of Patent: April 26, 2011
    Assignee: Bristol-Myers Squibb Company
    Inventors: Richard A. Hartz, Vijay T. Ahuja, Vivekananda M. Vrudhula, Joanne J. Bronson
  • ?-(N-sulfonamido)acetamide derivatives as ?-amyloid inhibitors
    Patent number: 7786122
    Abstract: There is provided a series of novel ?-(N-sulfonamido)acetamide compounds of the Formula (I) wherein R, R1, R2 and R3 are defined herein, which are inhibitors of ?-amyloid peptide (?-AP) production and are useful in the treatment of Alzheimer's Disease and other conditions affected by anti-amyloid activity.
    Type: Grant
    Filed: October 11, 2007
    Date of Patent: August 31, 2010
    Assignee: Bristol-Myers Squibb Company
    Inventors: Michael F. Parker, Katharine E. McElhone, Robert A. Mate, Joanne J. Bronson, Yonghua Gai, Carl P. Bergstrom, Lawrence R. Marcin, John E. Macor
  • Pyrazinone Modulator of Corticotropin-Releasing Factor Receptor Activity
    Publication number: 20100029684
    Abstract: The invention relates to the compound (S)-4-(1-cyclopropyl-2-methoxyethyl)-6-(6-(difluoromethoxy)-2,5-dimethylpyridin-3-ylamino)-5-oxo-4,5-dihydropyrazine-2-carbonitrile, pharmaceutical compositions of the compound, and methods of using the compound for the treatment of psychiatric disorders and neurological diseases including depression, anxiety related disorders, irritable bowel syndrome, addiction and negative aspects of drug and alcohol withdrawal, and other conditions associated with CRF.
    Type: Application
    Filed: April 24, 2009
    Publication date: February 4, 2010
    Inventors: Richard A. Hartz, Vijay T. Ahuja, Vivekananda M. Vrudhula, Joanne J. Bronson
  • Substituted heterocyclic ethers and their use in CNS disorders
    Patent number: 7632861
    Abstract: The invention encompasses compounds of Formula I, including pharmaceutically acceptable salts, their pharmaceutical compositions, and their use in treating CNS disorders.
    Type: Grant
    Filed: November 7, 2008
    Date of Patent: December 15, 2009
    Assignee: Bristol-Myers Squibb Company
    Inventors: Joanne J. Bronson, Andrew P. Degnan, William D. Schmitz
  • Substituted Heterocyclic Ethers and Their Use in CNS Disorders
    Publication number: 20090124613
    Abstract: The invention encompasses compounds of Formula I, including pharmaceutically acceptable salts, their pharmaceutical compositions, and their use in treating CNS disorders.
    Type: Application
    Filed: November 7, 2008
    Publication date: May 14, 2009
    Inventors: Joanne J. Bronson, Andrew P. Degnan, William D. Schmitz
  • Substituted Heterocyclic Ethers and Their Use in CNS Disorders
    Publication number: 20090030040
    Abstract: The invention encompasses compounds of Formula I, including pharmaceutically acceptable salts, their pharmaceutical compositions, and their use in treating CNS disorders.
    Type: Application
    Filed: January 25, 2008
    Publication date: January 29, 2009
    Inventors: Michael F. Parker, Joanne J. Bronson, Mark V. Silva, Kevin W. Gillman
  • Substituted Heterocyclic Ethers and Their Use in CNS Disorders
    Publication number: 20090018132
    Abstract: The invention encompasses compounds of Formula I, including pharmaceutically acceptable salts, their pharmaceutical compositions, and their use in treating CNS disorders.
    Type: Application
    Filed: July 1, 2008
    Publication date: January 15, 2009
    Inventors: Andrew P. Degnan, George O. Tora, Derek J. Denhart, Vivekananda M. Vrudhula, John E. Macor, Joanne J. Bronson
  • Substituted Heterocyclic Ethers and Their Use in CNS Disorders
    Publication number: 20090018163
    Abstract: The invention encompasses compounds of Formula I, including pharmaceutically acceptable salts, their pharmaceutical compositions, and their use in treating CNS disorders.
    Type: Application
    Filed: July 9, 2008
    Publication date: January 15, 2009
    Inventors: William D. Schmitz, Irene E. Whitney, Andrew P. Degnan, Joanne J. Bronson
  • SUBSTITUTED HETEROCYCLIC ETHERS AND THEIR USE IN CNS DISORDERS
    Publication number: 20080027056
    Abstract: The invention encompasses compounds of Formula I, including pharmaceutically acceptable salts, their pharmaceutical compositions, and their use in treating CNS disorders.
    Type: Application
    Filed: July 24, 2007
    Publication date: January 31, 2008
    Inventors: Michael F. Parker, Joanne J. Bronson, Mark V. Silva, Kevin W. Gillman
  • ?-(N-sulfonamido)acetamide derivatives as ?-amyloid inhibitors
    Patent number: 7300936
    Abstract: There is provided a series of novel ?-(N-sulfonamido)acetamide compounds of the Formula (I) wherein R, R1, R2 and R3 are defined herein, which are inhibitors of ?-amyloid peptide (?-AP) production and are useful in the treatment of Alzheimer's Disease and other conditions affected by anti-amyloid activity.
    Type: Grant
    Filed: December 20, 2002
    Date of Patent: November 27, 2007
    Assignee: Bristol-Myers Squibb Company
    Inventors: Michael F. Parker, Katharin E. McElhone, Robert A. Mate, Joanne J. Bronson, Yonghua Gai, Carl P. Bergstrom, Lawrence R. Marcin, John E. Macor
  • Arylpyrrolidine derivatives as NK-1 /SSRI antagonists
    Patent number: 7138423
    Abstract: The present disclosure relates to chemical compounds and their use in treatment of human diseases. A particular embodiment relates to compounds of Formula (I) or an isomer, a pharmaceutically acceptable salts or solvates thereof or a pharmaceutically acceptable formulation comprising said compounds are useful for the treatment or prevention of conditions mediated by tachykinins and/or selective inhibition of serotonin reuptake transporter protein. The compounds act as dual NK-1 antagonists and selective serotonin reuptake inhibitors.
    Type: Grant
    Filed: July 18, 2005
    Date of Patent: November 21, 2006
    Assignee: Bristol-Myers Squibb Company
    Inventors: Yong-Jin Wu, Huan He, Joanne J. Bronson
  • O-derivatized nocathiacin derivatives
    Patent number: 7022667
    Abstract: The present invention provides compounds of formula I having potent antibiotic activity, including activity towards Gram-positive bacteria and mycobacteria.
    Type: Grant
    Filed: July 3, 2002
    Date of Patent: April 4, 2006
    Assignee: Bristol-Myers Squibb Company
    Inventors: Thomas W. Hudyma, Xiaofan Zheng, B. Narasimhulu Naidu, Margaret E. Sorenson, Alicia Regueiro-Ren, Timothy P. Connolly, John D. Matiskella, Oak K. Kim, Yunhui Zhang, Dane M. Springer, Jason Goodrich, Yasutsugu Ueda, Joanne J. Bronson
  • Alpha-(N-sulfonamido)acetamide derivatives as beta-amyloid inhibitors
    Publication number: 20040127494
    Abstract: There is provided a series of novel &agr;-(N-sulfonamido)acetamide compounds of the Formula (I) 1
    Type: Application
    Filed: December 20, 2002
    Publication date: July 1, 2004
    Inventors: Michael F. Parker, Katharine E. McElhone, Robert A. Mate, Joanne J. Bronson, Yonghua Gai, Carl P. Bergstrom, Lawrence R. Marcin, John E. Macor
  • O-derivatized nocathiacin derivatives
    Publication number: 20040018963
    Abstract: The present invention provides compounds of formula I 1
    Type: Application
    Filed: July 3, 2002
    Publication date: January 29, 2004
    Inventors: Thomas W. Hudyma, Xiaofan Zheng, B. Narasimhulu Naidu, Margaret E. Sorenson, Alicia Regueiro-Ren, Timothy P. Connolly, John D. Matiskella, Oak K. Kim, Yunhui Zhang, Dane M. Springer, Jason Goodrich, Yasutsugu Ueda, Joanne J. Bronson
  • Water soluble thiazolyl peptide derivatives
    Publication number: 20020065219
    Abstract: Novel thiazolyl peptide compounds useful for the treatment of serious bacterial infections, and pharmaceutical compositions thereof are provided.
    Type: Application
    Filed: August 13, 2001
    Publication date: May 30, 2002
    Inventors: B. Narasimhulu Naidu, Wenying Li, Kin S. Lam, Margaret E. Sorenson, John A. Wichtowski, Timothy P. Connolly, Yasutsugu Ueda, Joanne J. Bronson, Yunhui Zhang, Oak K. Kim