Abstract: This invention relates to a synthetic method for the preparation of Compound 1 and precursors thereof. Compound 1 is prepared via reaction of isoxazole 2 with phenylether (R)-3-ONa.

Abstract: An aerosol container (10) dispenses a fluid product under pressure. A pressure relief mechanism (30) vents the container in a controlled manner when the container is subjected to excessive pressure so to prevent the container from bursting. The container has a container body (12) of a hollow, generally cylindrical shape. Pressurized contents of the container are expelled through a valve assembly (18) installed at one end of the container. An end piece (22) attached to the container body at the other end of the container has a first circular shaped section (26) surrounded by a ring shaped outer section (28). The pressure relief mechanism comprises U-shaped score lines (32) formed across the transition between the two sections of the end piece. These score lines create lines of weakness in the material from which the end piece is made for the end piece to fracture along the score lines when the pressure within the container exceeds a predetermined pressure level.

Abstract: An aerosol container (10) dispenses a fluid product under pressure. A pressure relief mechanism (30) vents the container in a controlled manner when the container is subjected to excessive pressure so to prevent the container from bursting. The container has a container body (12) of a hollow, generally cylindrical shape. Pressurized contents of the container are expelled through a valve assembly (18) installed at one end of the container. An end piece (22) attached to the container body at the other end of the container has a first circular shaped section (26) surrounded by a ring shaped outer section (28). The pressure relief mechanism comprises U-shaped score lines (32) formed across the transition between the two sections of the end piece. These score lines create lines of weakness in the material from which the end piece is made for the end piece to fracture along the score lines when the pressure within the container exceeds a predetermined pressure level.

Abstract: A special article printing press includes a mandrel wheel for supporting an elongated article for printing thereon, a blanket cylinder for transferring ink onto the elongated article, a plate cylinder for selectively transferring ink to a section of the blanket cylinder, at least one inker for transferring ink onto a plate cylinder, a frame for holding the at least one inker, and an inker stabilizer configured to stabilize the inker or frame with respect to the plate cylinder, printing press, or blanket cylinder.