Abstract: Aspects described herein are directed to compositions, systems, and methods of manufacturing a polymer-based construction material comprising polymeric resin and filler such as calcium carbonate (CaCO3). A surface of the polymer-based construction material may be treated such that the surface energy is increased from the material's inherent value to a predetermined value of at least 40 dynes/cm2. Further, the surface energy of the treated surface may persist within 20% of the predetermined value for at least three days.

Abstract: Implementations of the disclosed subject matter may provide a method of retrieving a data record including historic utility bill statements of a customer, determining a historic energy usage rate of the customer based on the retrieved data record, and determining whether the customer is eligible to subscribe to a community solar energy generating system based on geographic location of the community solar energy generating system, the determined historic energy usage rate of the customer, and the customer's geographic location. The method may determine an allocation of energy produced by the community solar energy generating system when the eligible customer is enrolled in a subscription to the community solar energy generating system. The method may generate a customer data record for the user based on credits for the allocation of energy of the community solar energy generating system and receiving energy from another energy generating system.

Abstract: Aspects described herein are directed to compositions, systems, and methods of manufacturing a polymer-based construction material comprising polymeric resin and filler such as calcium carbonate (CaCO3). A surface of the polymer-based construction material may be treated such that the surface energy is increased from the material's inherent value to a predetermined value of at least 40 dynes/cm2. Further, the surface energy of the treated surface may persist within 20% of the predetermined value for at least three days.

Abstract: Aspects described herein are directed to compositions, systems, and methods of manufacturing a polymer-based construction material comprising polymeric resin, filler such as calcium carbonate (CaCO3), and titanium oxide (TiO2). A surface of the polymer-based construction material may be treated such that the surface energy is increased from the material's inherent value to a predetermined value of at least 40 dynes/cm2. Further, the surface energy of the treated surface may persist within 20% of the predetermined value for at least three days.

Abstract: Methods and compositions are provided for determining TMB in a tumor sample using transcriptome profiling data. Also provided herein are methods and compositions for determining the response of an individual with a specific TMB to a therapy such as immunotherapy.

Abstract: Methods and compositions are provided for determining a pan-cancer clustering of cluster assignment (COCA) subtype of a cancer in an individual by detecting the expression level of at least one classifier biomarker selected from a group of classifier biomarkers for COCA subtypes. Also provided herein are methods and compositions for determining the response of an individual with a COCA subtype to a therapy such as immunotherapy.

Abstract: A document source identification system includes one or more memory devices storing instructions, and one or more processors configured to execute the instructions to cause the system to receive uploaded document(s) having at least one extractable data entry. The system may categorize the document, and extract at least one data entry from the document. The system may normalize each extracted data entry and execute a deterministic ID search to determine that the normalized data entry matches zero, one, or more than one account data entries associated with user accounts. Responsive to an exact match, the system may link the uploaded document to a user account associated with the matching data entry. Responsive to zero or multiple matches, the system may execute a probabilistic ID search identifying a highest ranked user account data entry and link the document to a user account associated with the highest ranked user account data entry.

Abstract: Polymeric-based building materials are disclosed. The polymeric-based building materials can include opposing inner and outer surfaces, with a recessed portion on the inner surface that is positioned between a first contacting portion and a second contacting portion. The surface of the second contacting portion can be angled with respect to the surface of the first contacting portion.

Abstract: A document source identification system includes one or more memory devices storing instructions, and one or more processors configured to execute the instructions to cause the system to receive uploaded document(s) having at least one extractable data entry. The system may categorize the document, and extract at least one data entry from the document. The system may normalize each extracted data entry and execute a deterministic ID search to determine that the normalized data entry matches zero, one, or more than one account data entries associated with user accounts. Responsive to an exact match, the system may link the uploaded document to a user account associated with the matching data entry. Responsive to zero or multiple matches, the system may execute a probabilistic ID search identifying a highest ranked user account data entry and link the document to a user account associated with the highest ranked user account data entry.

Abstract: Aspects described herein are directed to compositions, systems, and methods of manufacturing a polymer-based construction material comprising polymeric resin, filler such as calcium carbonate (CaCO3), and titanium oxide (TiO2). A surface of the polymer-based construction material may be treated such that the surface energy is increased from the material's inherent value to a predetermined value of at least 40 dynes/cm2. Further, the surface energy of the treated surface may persist within 20% of the predetermined value for at least three days.

Abstract: A document source identification system includes one or more memory devices storing instructions, and one or more processors configured to execute the instructions to cause the system to receive uploaded document(s) having at least one extractable data entry. The system may categorize the document, and extract at least one data entry from the document. The system may normalize each extracted data entry and execute a deterministic ID search to determine that the normalized data entry matches zero, one, or more than one account data entries associated with user accounts. Responsive to an exact match, the system may link the uploaded document to a user account associated with the matching data entry. Responsive to zero or multiple matches, the system may execute a probabilistic ID search identifying a highest ranked user account data entry and link the document to a user account associated with the highest ranked user account data entry.

Abstract: A document source identification system includes one or more memory devices storing instructions, and one or more processors configured to execute the instructions to cause the system to receive uploaded document(s) having at least one extractable data entry. The system may categorize the document, and extract at least one data entry from the document. The system may normalize each extracted data entry and execute a deterministic ID search to determine that the normalized data entry matches zero, one, or more than one account data entries associated with user accounts. Responsive to an exact match, the system may link the uploaded document to a user account associated with the matching data entry. Responsive to zero or multiple matches, the system may execute a probabilistic ID search identifying a highest ranked user account data entry and link the document to a user account associated with the highest ranked user account data entry.

Abstract: Provided herein are compositions and methods for predicting whether a subject with cancer will be responsive to treatment with an EGFR TKI and for the treatment of cancer in a subject.

Abstract: The application provides methods of prognosing and classifying lung cancer patients into poor survival groups or good survival groups and for determining the benefit of adjuvant chemotherapy by way of a multigene signature. The application also includes kits and computer products for use in the methods of the application.

Abstract: Methods and systems are provided for performing allelic copy number association in genome-wide association studies. Also provided are computer-readable media for storing instructions for performing the genomic marker association studies. The methods include performing genomic marker association studies wherein allelic contrast and copy number are analyzed simultaneously, comprising the steps of receiving measurements of intensity for each of two alleles (A and B) in a biological sample set; computing a sum value (S) and a difference value (D) of the intensities; and employing a statistical model to determine a potential association of the S and/or the D value with an outcome, wherein a statistically significant coefficient of the S intensity indicates an association of the copy number with the outcome and a statistically significant coefficient of the D intensity indicates an association of the allelic contrast with the outcome.

Abstract: A system for and method of remotely controlling a recording device is disclosed. In one embodiment, the system comprises a program server coupled to a signal transmitter. The program server is configured to (1) allow searching a pool of programs from which one or more programs are selected for recording, (2) translate information related to the selected programs into one or more control codes used to control a recording device for recording the selected programs, and (3) transmit the control codes to the signal transmitter. The signal transmitter is configured to receive the control codes and store them. The signal transmitter is further configured to emit control signals containing the control codes and used to control the recording device to record the selected programs, either manually or by programming the recording the device to record the programs at a later date and time.