Patents by Inventor Joel Berniac

Joel Berniac has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SUBSTITUTED TETRACYCLINE COMPOUNDS
    Publication number: 20170305840
    Abstract: The present invention pertains, at least in part, to novel substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for tetracycline compounds such as blocking tetracycline efflux and modulation of gene expression.
    Type: Application
    Filed: December 9, 2016
    Publication date: October 26, 2017
    Inventors: Mark L. Nelson, Kwasi Ohemeng, Paul Abato, Victor Amoo, Haregewein Assefa, Joel Berniac, Beena Bhatia, Todd Bowser, Jackson Chen, Mark Grier, Laura Honeyman, Mohamed Y. Ismail, Oak K. Kim, Jude Mathews, Rachid Mechiche
  • 11a, 12-DERIVATIVES OF TETRACYCLINE COMPOUNDS
    Publication number: 20160039749
    Abstract: 11a,12-dehydrotetracycline compounds are described.
    Type: Application
    Filed: May 23, 2013
    Publication date: February 11, 2016
    Inventors: Joel Berniac, Mohamed Y. Ismail, Mark L. Nelson, Farzaneh Seyedi
  • MIXED PAYLOAD CONTAINING POLYMERS AND USE THEREOF
    Publication number: 20150355187
    Abstract: The invention provides methods for delivery of payloads to targets in samples using mixed payload polymers. The invention further provides reagents and kits for practicing the methods of the invention. The invention also provides methods for preparation of reagents for use in the methods of the invention.
    Type: Application
    Filed: December 19, 2013
    Publication date: December 10, 2015
    Inventors: Joel Berniac, Rajiv Panwar
  • SUBSTITUTED TETRACYCLINE COMPOUNDS
    Publication number: 20150045329
    Abstract: The present invention pertains, at least in part, to novel substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for tetracycline compounds such as blocking tetracycline efflux and modulation of gene expression.
    Type: Application
    Filed: May 19, 2014
    Publication date: February 12, 2015
    Applicant: Paratek Pharmaceuticals, Inc.
    Inventors: Mark L. Nelson, Kwasi Ohemeng, Paul Abato, Victor Amoo, Haregewein Assefa, Joel Berniac, Beena Bhatia, Todd Bowser, Jackson Chen, Mark Grier, Laura Honeyman, Mohamed Y. Ismail, Oak K. Kim, Jude Mathews, Rachid Mechiche
  • REAGENTS AND METHODS FOR BISPECIFIC ANTIBODY-BASED BINDING OF TARGET MOLECULES
    Publication number: 20140186850
    Abstract: The invention provides methods for delivery of payloads to targets in samples using non-sterically hindered complexes. The invention further provides reagents and kits for practicing the methods of the invention. The invention also provides methods for preparation of reagents for use in the methods of the invention.
    Type: Application
    Filed: December 19, 2013
    Publication date: July 3, 2014
    Applicant: AKRIVIS TECHNOLOGIES, LLC
    Inventors: Joel Berniac, Peter Donovan, Ban-An Khaw, Vishwesh Patil
  • SUBSTITUTED TETRACYCLINE COMPOUNDS
    Publication number: 20140155357
    Abstract: The present invention pertains, at least in part, to novel substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for tetracycline compounds such as blocking tetracycline efflux and modulation of gene expression.
    Type: Application
    Filed: June 14, 2013
    Publication date: June 5, 2014
    Inventors: Paul Abato, Haregewein Assefa, Joel Berniac, Beena Bhatia, Todd Bowser, Jackson Chen, Mark Grier, Laura Honeyman, Mohamed Y. Ismail, Mark L. Nelson, Kwasi Ohemeng, Jingwen Pan
  • 11a, 12-derivatives of tetracycline compounds
    Patent number: 8470804
    Abstract: 11a,12-dehydrotetracycline compounds are described.
    Type: Grant
    Filed: December 29, 2011
    Date of Patent: June 25, 2013
    Assignee: Paratek Pharmaceuticals, Inc.
    Inventors: Joel Berniac, Mohamed Y. Ismail, Mark L. Nelson, Faye Seyedi
  • Substituted tetracycline compounds
    Patent number: 8466132
    Abstract: The present invention pertains, at least in part, to novel substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for tetracycline compounds such as blocking tetracycline efflux and modulation of gene expression.
    Type: Grant
    Filed: October 25, 2005
    Date of Patent: June 18, 2013
    Assignee: Paratek Pharmaceuticals, Inc.
    Inventors: Paul Abato, Haregewein Assefa, Joel Berniac, Beena Bhatia, Todd Bowser, Jackson Chen, Mark Grier, Laura Honeyman, Mohamed Y. Ismail, Mark L. Nelson, Kwasi Ohemeng, Jingwen Pan
  • Methods for treating spinal muscular atrophy using tetracycline compounds
    Patent number: 8399437
    Abstract: Methods for using tetracycline compounds for the treatment of spinal muscular atrophy are described.
    Type: Grant
    Filed: May 3, 2011
    Date of Patent: March 19, 2013
    Assignee: Paratek Pharmaceuticals, Inc.
    Inventors: Joel Berniac, Todd Bowser, Michael P. Draper, Stuart B. Levy, Mark L. Nelson
  • 11a, 12-Derivatives of Tetracycline Compounds
    Publication number: 20120101070
    Abstract: 11a,12-dehydrotetracycline compounds are described.
    Type: Application
    Filed: December 29, 2011
    Publication date: April 26, 2012
    Applicant: Paratek Pharmaceuticals, Inc.
    Inventors: Joel Berniac, Mohamed Y. Ismail, Mark L. Nelson, Faye Seyedi
  • 11a, 12-derivatives of tetracycline compounds
    Patent number: 8088755
    Abstract: 11a,12-dehydrotetracycline compounds are described.
    Type: Grant
    Filed: February 6, 2006
    Date of Patent: January 3, 2012
    Assignee: Paratek Pharmaceuticals, Inc.
    Inventors: Joel Berniac, Mohamed Y. Ismail, Mark L. Nelson, Faye Seyedi
  • Methods for Treating Spinal Muscular Atrophy Using Tetracycline Compounds
    Publication number: 20110207706
    Abstract: Methods for using tetracycline compounds for the treatment of spinal muscular atrophy are described.
    Type: Application
    Filed: May 3, 2011
    Publication date: August 25, 2011
    Applicant: Paratek Pharmaceuticals, Inc.
    Inventors: Joel Berniac, Todd Bowser, Michael Draper, Stuart B. Levy, Mark L. Nelson
  • Methods for treating spinal muscular atrophy using tetracycline compounds
    Patent number: 7935687
    Abstract: Methods for using tetracycline compounds for the treatment of spinal muscular atrophy are described.
    Type: Grant
    Filed: April 14, 2008
    Date of Patent: May 3, 2011
    Assignee: Paratek Pharmaceuticals, Inc.
    Inventors: Joel Berniac, Todd Bowser, Michael Draper, Stuart B. Levy, Mark L. Nelson
  • Substituted Tetracycline Compounds
    Publication number: 20110086822
    Abstract: The present invention pertains, at least in part, to novel substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.
    Type: Application
    Filed: October 8, 2010
    Publication date: April 14, 2011
    Inventors: Mark L. Nelson, Kwasi Ohemeng, Roger Frechette, Paul Abato, Victor Amoo, Upul Bandarage, Joel Berniac, Beena Bhatia, Jackson Chen, Mohamed Y. Ismail, Oak Kim, Laura Honeyman, Rachid Mechiche, Andre Pearson, Laxma Reddy Nagavelli, Paul Sheahan, Atul K. Verma, Peter Viski, Tadeusz Warchol
  • 4-Substituted Tetracyclines and Methods of Use Thereof
    Publication number: 20110077225
    Abstract: The present invention pertains, at least in part, to novel substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for tetracycline compounds such as blocking tetracycline efflux and modulation of gene expression.
    Type: Application
    Filed: December 7, 2010
    Publication date: March 31, 2011
    Applicant: Paratek Pharmaceuticals, Inc.
    Inventors: Joel Berniac, Beena Bhatia, Mark Grier, Mark L. Nelson, Jingwen Pan
  • 4-substituted tetracyclines and methods of use thereof
    Patent number: 7858601
    Abstract: The present invention pertains, at least in part, to novel substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for tetracycline compounds such as blocking tetracycline efflux and modulation of gene expression.
    Type: Grant
    Filed: October 25, 2005
    Date of Patent: December 28, 2010
    Assignee: Paratek Pharmaceuticals, Inc.
    Inventors: Joel Berniac, Beena Bhatia, Mark Grier, Mark L. Nelson, Jingwen Pan
  • PRODRUGS OF 9-AMINOMETHYL TETRACYCLINE COMPOUNDS
    Publication number: 20100249076
    Abstract: The invention pertains to prodrugs of 9-aminomethyl substituted tetracycline compounds, methods of using the compounds, and pharmaceutical compositions containing them.
    Type: Application
    Filed: June 3, 2010
    Publication date: September 30, 2010
    Applicant: Paratek Pharmaceuticals, Inc.
    Inventors: Victor Amoo, Haregewein Assefa, Beena Bhatia, Joel Berniac, Todd Bowser, Jackson Chen, Mark Grier, Laura Honeyman, Oak K. Kim, Rachid Mechiche, Kwasi Ohemeng, Jingwen Pan
  • Substituted Tetracycline Compounds
    Publication number: 20100022483
    Abstract: The present invention pertains, at least in part, to methods of treating a microorganism-associated infection in a subject comprising administering to said subject an effective amount of a tetracycline compound.
    Type: Application
    Filed: April 14, 2009
    Publication date: January 28, 2010
    Applicant: Paratek Pharmaceuticals, Inc.
    Inventors: Joel Berniac, Todd Bowser
  • Methods for Treating Spinal Muscular Atrophy Using Tetracycline Compounds
    Publication number: 20090118269
    Abstract: Methods for using tetracycline compounds for the treatment of spinal muscular atrophy are described.
    Type: Application
    Filed: April 14, 2008
    Publication date: May 7, 2009
    Inventors: Joel Berniac, Todd Bowser, Michael Draper, Stuart B. Levy, Mark L. Nelson
  • Amino-methyl substituted tetracycline compounds
    Patent number: 7326696
    Abstract: Aminomethyl substituted tetracycline compounds, pharmaceutical compositions, and methods of use thereof are discussed.
    Type: Grant
    Filed: December 15, 2003
    Date of Patent: February 5, 2008
    Assignee: Paratek Pharmaceuticals, Inc.
    Inventors: Mark L. Nelson, Kwasi Ohemeng, Roger Frechette, Paul Abato, Victor Amoo, Haregewein Assefa, Joel Berniac, Beena Bhatia, Todd Bowser, Jackson Chen, Laura Honeyman, Mohamed Y. Ismail, Oak Kim, Rachid Mechiche, N. Laxma Reddy, Atul K. Verma, Peter Viski, Tadeusz Warchol, Ivan Yanachkov