Patents by Inventor Joel N. Hirschhorn

Joel N. Hirschhorn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Generic SBE-FRET protocol
    Patent number: 6642001
    Abstract: The present invention is drawn to methods for detection, quantitation and analysis of nucleotides of interest in nucleic acid sequences of interest using single base extension and fluorescence resonance energy transfer and generic donor molecule-labeled detection probes.
    Type: Grant
    Filed: July 13, 2000
    Date of Patent: November 4, 2003
    Assignee: Whitehead Institute for Biomedical Research
    Inventors: Stacey Bolk, Joel N. Hirschhorn, James S. Ireland, Eric S. Lander
  • Association of protein kinase C zeta polymorphisms with diabetes
    Publication number: 20030175797
    Abstract: A central role for the gene encoding protein kinase C zeta in diabetes and perhaps in related disorders is disclosed. Use of single nucleotide polymorphisms in the protein kinase C zeta gene for diagnosis, prediction of clinical course and treatment response, development of new treatments and development of cell-culture based and animal models for research and treatment are disclosed.
    Type: Application
    Filed: May 13, 2003
    Publication date: September 18, 2003
    Applicant: Whitehead Institute for Biomedical Research
    Inventors: David M. Altshuler, Joel N. Hirschhorn, Eric S. Lander
  • Association of protein kinase C zeta polymorphisms with diabetes
    Patent number: 6562574
    Abstract: A central role for the gene encoding protein kinase C zeta in diabetes and perhaps in related disorders is disclosed. Use of single nucleotide polymorphisms in the protein kinase C zeta gene for diagnosis, prediction of clinical course and treatment response, development of new treatments and development of cell-culture based and animal models for research and treatment are disclosed.
    Type: Grant
    Filed: April 25, 2001
    Date of Patent: May 13, 2003
    Assignees: Whitehead Institute for Biomedical Research, The General Hospital Corporation
    Inventors: David M. Altshuler, Joel N. Hirschhorn, Eric S. Lander
  • Association of protein kinase C zeta polymorphisms with diabetes
    Publication number: 20020137048
    Abstract: A central role for the gene encoding protein kinase C zeta in diabetes and perhaps in related disorders is disclosed. Use of single nucleotide polymorphisms in the protein kinase C zeta gene for diagnosis, prediction of clinical course and treatment response, development of new treatments and development of cell-culture based and animal models for research and treatment are disclosed.
    Type: Application
    Filed: April 25, 2001
    Publication date: September 26, 2002
    Applicant: Whitehead Institute for Biomedical Research
    Inventors: David M. Altshuler, Joel N. Hirschhorn, Eric S. Lander
  • Methods for selecting primers
    Patent number: 6440675
    Abstract: Methods for selecting primers having a reduced incidence of undesirable interactions are disclosed. Methods of improving the accuracy of SBE-fluorescence polarization (SBE-FP) methods are also disclosed.
    Type: Grant
    Filed: September 18, 2000
    Date of Patent: August 27, 2002
    Assignee: Whitehead Institute for Biomedical Research
    Inventors: Kerstin A. Lindblad-Toh, Ellen Winchester, Joel N. Hirschhorn, Pamela Sklar