Patents by Inventor Joffre B. Baker

Joffre B. Baker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR USING GENE EXPRESSION TO DETERMINE PROGNOSIS OF PROSTATE CANCER
    Publication number: 20220396842
    Abstract: The present disclosure includes assays that involve measurement of expression levels of prognostic biomarkers, or co-expressed biomarkers, from a biological sample obtained from a prostate cancer patient, and analysis of the measured expression levels to provide information concerning the likely prognosis for the patient, and likelihood that the patient will have a recurrence of prostate cancer, or to classify the tumor by likelihood of clinical outcome or TMPRSS2 fusion status.
    Type: Application
    Filed: August 19, 2022
    Publication date: December 15, 2022
    Inventors: Steven SHAK, Frederick L. Baehner, Tara MADDALA, Mark LEE, Robert J. PELHAM, Wayne COWENS, Diana CHERBAVAZ, Michael C. KIEFFER, Michael CRAGER, Audrey GODDARD, Joffre B. BAKER
  • Gene expression markers for breast cancer prognosis
    Patent number: 11220715
    Abstract: The present invention provides gene sets the expression of which is important in the diagnosis and/or prognosis of breast cancer.
    Type: Grant
    Filed: February 15, 2018
    Date of Patent: January 11, 2022
    Assignee: Genomic Health, Inc.
    Inventors: Melody A. Cobleigh, Steven Shak, Joffre B. Baker, Maureen T. Cronin
  • METHODS TO PREDICT CLINICAL OUTCOME OF CANCER
    Publication number: 20210062275
    Abstract: The present invention provides methods to determine the prognosis and appropriate treatment for patients diagnosed with cancer, based on the expression levels of one or more biomarkers. More particularly, the invention relates to the identification of genes, or sets of genes, able to distinguish breast cancer patients with a good clinical prognosis from those with a bad clinical prognosis. The invention further provides methods for providing a personalized genomics report for a cancer patient. The inventions also relates to computer systems and software for data analysis using the prognostic and statistical methods disclosed herein.
    Type: Application
    Filed: September 11, 2020
    Publication date: March 4, 2021
    Applicant: GENOMIC HEALTH, INC.
    Inventors: Joffre B. BAKER, Maureen T. CRONIN, Francois COLLIN, Mei-Lan LIU
  • Prediction of Likelihood of Cancer Recurrence
    Publication number: 20200299781
    Abstract: The present invention provides gene sets the expression of which is important in the diagnosis and/or prognosis of cancer, in particular of breast cancer.
    Type: Application
    Filed: March 3, 2020
    Publication date: September 24, 2020
    Applicant: Genomic Health, Inc.
    Inventors: Joffre B. Baker, John L. Bryant, Soonmyung Paik, Steven Shak
  • METHOD OF PREDICTING BREAST CANCER PROGNOSIS
    Publication number: 20200263257
    Abstract: The present invention relates to biomarkers associated with breast cancer prognosis. These biomarkers include coding transcripts and their expression products, as well as non-coding transcripts, and are useful for predicting the likelihood of breast cancer recurrence in a breast cancer patient. The present invention also relates to a novel method of identifying intergenic sequences that correlate with a clinical outcome.
    Type: Application
    Filed: February 7, 2020
    Publication date: August 20, 2020
    Applicant: GENOMIC HEALTH, INC.
    Inventors: Joffre B. BAKER, Dominick SINICROPI, Robert J. PELHAM, Michael R. CRAGER, Francois COLLIN, James C. STEPHANS, Mei-Lan LIU, John D. MORLAN, Kunbin QU
  • Method for Using Gene Expression to Determine Prognosis of Prostate Cancer
    Publication number: 20200255911
    Abstract: Molecular assays that involve measurement of expression levels of prognostic biomarkers, or co-expressed biomarkers, from a biological sample obtained from a prostate cancer patient, and analysis of the measured expression levels to provide information concerning the likely prognosis for said patient, and likelihood that said patient will have a recurrence of prostate cancer, or to classify the tumor by likelihood of clinical outcome or TMPRSS2 fusion status, are provided herein.
    Type: Application
    Filed: February 25, 2020
    Publication date: August 13, 2020
    Applicant: GENOMIC HEALTH, INC.
    Inventors: Steven SHAK, Frederick L. BAEHNER, Tara MADDALA, Mark LEE, Robert J. PELHAM, Wayne COWENS, Diana CHERBAVAZ, Michael C. KIEFER, Michael CRAGER, Audrey GODDARD, Joffre B. BAKER
  • Prediction of likelihood of cancer recurrence
    Patent number: 10619215
    Abstract: The present invention provides gene sets the expression of which is important in the diagnosis and/or prognosis of cancer, in particular of breast cancer.
    Type: Grant
    Filed: August 11, 2017
    Date of Patent: April 14, 2020
    Assignee: Genomic Health, Inc.
    Inventors: Joffre B. Baker, John L. Bryant, Soonmyung Paik, Steven Shak
  • Methods of Incorporation of Transcript Chromosomal Locus Information for Identification of Biomarkers of Disease Recurrence Risk
    Publication number: 20200105367
    Abstract: The present invention provides methods for incorporating transcript chromosomal locus information for identification of biomarkers of disease recurrence risk.
    Type: Application
    Filed: September 27, 2019
    Publication date: April 2, 2020
    Applicant: Genomic Health, Inc.
    Inventors: Michael C. Kiefer, Francois Collin, Samuel Levy, Joffre B. Baker, Michael R. Crager, Mark R. Segal
  • METHOD OF PREDICTING BREAST CANCER PROGNOSIS
    Publication number: 20190256923
    Abstract: The present invention relates to biomarkers associated with breast cancer prognosis. These biomarkers include coding transcripts and their expression products, as well as non-coding transcripts, and are useful for predicting the likelihood of breast cancer recurrence in a breast cancer patient. The present invention also relates to a novel method of identifying intergenic sequences that correlate with a clinical outcome.
    Type: Application
    Filed: January 17, 2019
    Publication date: August 22, 2019
    Applicant: GENOMIC HEALTH, INC.
    Inventors: Joffre B. BAKER, Dominick SINICROPI, Robert J. PELHAM, Michael R. CRAGER, Francois COLLIN, James C. STEPHANS, Mei-Lan LIU, John D. MORLAN, Kunbin QU
  • Method for Using Gene Expression to Determine Prognosis of Prostate Cancer
    Publication number: 20190249260
    Abstract: Molecular assays that involve measurement of expression levels of prognostic biomarkers, or co-expressed biomarkers, from a biological sample obtained from a prostate cancer patient, and analysis of the measured expression levels to provide information concerning the likely prognosis for said patient, and likelihood that said patient will have a recurrence of prostate cancer, or to classify the tumor by likelihood of clinical outcome or TMPRSS2 fusion status, are provided herein.
    Type: Application
    Filed: February 22, 2019
    Publication date: August 15, 2019
    Applicant: GENOMIC HEALTH, INC.
    Inventors: Steven SHAK, Frederick L. BAEHNER, Tara MADDALA, Mark LEE, Robert J. PELHAM, Wayne COWENS, Diana CHERBAVAZ, Michael C. KIEFER, Michael CRAGER, Audrey GODDARD, Joffre B. BAKER
  • METHODS TO PREDICT CLINICAL OUTCOME OF CANCER
    Publication number: 20190241967
    Abstract: The present invention provides methods to determine the prognosis and appropriate treatment for patients diagnosed with cancer, based on the expression levels of one or more biomarkers. More particularly, the invention relates to the identification of genes, or sets of genes, able to distinguish breast cancer patients with a good clinical prognosis from those with a bad clinical prognosis. The invention further provides methods for providing a personalized genomics report for a cancer patient. The inventions also relates to computer systems and software for data analysis using the prognostic and statistical methods disclosed herein.
    Type: Application
    Filed: January 9, 2019
    Publication date: August 8, 2019
    Applicant: GENOMIC HEALTH, INC.
    Inventors: Joffre B. BAKER, Maureen T. CRONIN, Francois COLLIN, Mei-Lan LIU
  • Method for using gene expression to determine prognosis of prostate cancer
    Patent number: 10260104
    Abstract: The present disclosure includes assays that involve measurement of expression levels of prognostic biomarkers, or co-expressed biomarkers, from a biological sample obtained from a prostate cancer patient, and analysis of the measured expression levels to provide information concerning the likely prognosis for the patient, and likelihood that the patient will have a recurrence of prostate cancer, or to classify the tumor by likelihood of clinical outcome or TMPRSS2 fusion status.
    Type: Grant
    Filed: October 20, 2015
    Date of Patent: April 16, 2019
    Assignee: Genomic Health, Inc.
    Inventors: Steven Shak, Frederick L. Baehner, Tara Maddala, Mark Lee, Robert J. Pelham, Wayne Cowens, Diana Cherbavaz, Michael C. Kiefer, Michael Crager, Audrey Goddard, Joffre B. Baker
  • Gene expression profiling in biopsied tumor tissues
    Patent number: 10241114
    Abstract: The invention concerns sensitive methods to measure mRNA levels in biopsied tumor tissues, including archived paraffin-embedded biopsy material. The invention also concerns breast cancer gene sets important in the diagnosis and treatment of breast cancer, and methods for assigning the most optimal treatment options to breast cancer patient based upon knowledge derived from gene expression studies.
    Type: Grant
    Filed: June 9, 2006
    Date of Patent: March 26, 2019
    Assignee: Genomic Health, Inc.
    Inventors: Joffre B. Baker, Maureen T. Cronin, Michael C. Kiefer, Steve Shak, Michael Graham Walker
  • GENE EXPRESSION MARKERS FOR BREAST CANCER PROGNOSIS
    Publication number: 20180230548
    Abstract: The present invention provides gene sets the expression of which is important in the diagnosis and/or prognosis of breast cancer.
    Type: Application
    Filed: February 15, 2018
    Publication date: August 16, 2018
    Applicant: Genomic Health, Inc.
    Inventors: Melody A. Cobleigh, Steven Shak, Joffre B. Baker, Maureen T. Cronin
  • Gene expression markers for breast cancer prognosis
    Patent number: 9944990
    Abstract: The present invention provides gene sets the expression of which is important in the diagnosis and/or prognosis of breast cancer.
    Type: Grant
    Filed: April 21, 2014
    Date of Patent: April 17, 2018
    Assignee: GENOMIC HEALTH, INC.
    Inventors: Melody A. Cobleigh, Steven Shak, Joffre B. Baker, Maureen T. Cronin
  • PREDICTION OF LIKELIHOOD OF CANCER RECURRENCE
    Publication number: 20180051348
    Abstract: The present invention provides gene sets the expression of which is important in the diagnosis and/or prognosis of cancer, in particular of breast cancer.
    Type: Application
    Filed: August 11, 2017
    Publication date: February 22, 2018
    Applicants: Genomic Health, Inc., NSABP Foundation, Inc.
    Inventors: Joffre B. BAKER, John L. BRYANT, Soonmyung PAIK, Steven SHAK
  • METHODS TO PREDICT CLINICAL OUTCOME OF CANCER
    Publication number: 20170211154
    Abstract: The present invention provides methods to determine the prognosis and appropriate treatment for patients diagnosed with cancer, based on the expression levels of one or more biomarkers. More particularly, the invention relates to the identification of genes, or sets of genes, able to distinguish breast cancer patients with a good clinical prognosis from those with a bad clinical prognosis. The invention further provides methods for providing a personalized genomics report for a cancer patient. The inventions also relates to computer systems and software for data analysis using the prognostic and statistical methods disclosed herein.
    Type: Application
    Filed: February 3, 2017
    Publication date: July 27, 2017
    Applicant: GENOMIC HEALTH, INC.
    Inventors: Joffre B. BAKER, Maureen T. CRONIN, Francois COLLIN, Mei-Lan LIU
  • Gene expression markers for predicting response to chemotherapy
    Patent number: 9605318
    Abstract: The present invention provides sets of genes the expression of which is important in the prognosis of cancer. In particular, the invention provides gene expression information useful for predicting whether cancer patients are likely to have a beneficial treatment response to chemotherapy FHIT; MTA1; ErbB4; FUS; BBC3; IGF1R; CD9; TP53BP1; MUC1; IGFBP5; rhoC; RALBP1; STAT3; ERK1; SGCB; DHPS; MGMT; CRIP2; ErbB3; RAP1GDS1; CCND1; PRKCD; Hepsin; AK055699; ZNF38; SEMA3F; COL1A1; BAG1; AKT1; COL1A2; Wnt.5a; PTPD1; RAB6C; GSTM1, BCL2, ESR1; or the corresponding expression product, is determined, said report includes a prediction that said subject has a decreased likelihood of response to chemotherapy.
    Type: Grant
    Filed: November 8, 2010
    Date of Patent: March 28, 2017
    Assignee: Genomic Health, Inc.
    Inventors: Joffre B. Baker, Steven Shak, Luca Gianni
  • METHODS OF INCORPORATION OF TRANSCRIPT CHROMOSOMAL LOCUS INFORMATION FOR IDENTIFICATION OF BIOMARKERS OF DISEASE RECURRENCE RISK
    Publication number: 20160259881
    Abstract: The present invention provides methods for incorporating transcript chromosomal locus information for identification of biomarkers of disease recurrence risk.
    Type: Application
    Filed: October 28, 2014
    Publication date: September 8, 2016
    Inventors: Michael C. Kiefer, Francois Collin, Samuel Levy, Joffre B. Baker, Michael R. Crager, Mark R. Segal
  • METHOD OF PREDICTING BREAST CANCER PROGNOSIS
    Publication number: 20160222463
    Abstract: The present invention relates to biomarkers associated with breast cancer prognosis. These biomarkers include coding transcripts and their expression products, as well as non-coding transcripts, and are useful for predicting the likelihood of breast cancer recurrence in a breast cancer patient, The present invention also relates to a novel method of identifying intergenic sequences that correlate with a clinical outcome.
    Type: Application
    Filed: January 29, 2016
    Publication date: August 4, 2016
    Applicant: GENOMIC HEALTH, INC.
    Inventors: Joffre B. BAKER, Dominick S. SINICROPI, Robert J. PELHAM, Michael R. CRAGER, Francois COLLIN, James C. STEPHANS, Mei-Lan LIU, John D. MORLAN, Kunbin QU