Abstract: The disclosure provides a method for operating an automatically driving vehicle, wherein application instances are executed over several computational nodes, wherein recognized faults are reacted to by switching to redundant application instances and then reconfiguring the configuration to restore specified redundancy conditions and/or segregation conditions, wherein the vehicle is transitioned to a safe state using at least one failover apparatus when at least one specified redundancy condition and/or at least one segregation condition cannot be met by the reconfiguration, and/or a specified time for reconfiguration is exceeded, and/or an unrecoverable malfunction has been recognized, wherein the at least one failover apparatus plans an emergency trajectory using a trajectory planner, wherein sensor data are detected via separate signal lines and supplied to the at least one failover apparatus, and wherein control signals are generated and transmitted via separate control lines to an actuator system of the v

Abstract: The invention relates to a method for operating a self-propelled motor vehicle having a plurality of control units and a plurality of program codes for controlling the function of autonomous driving and possibly other functions of the self-propelled vehicle, wherein a plurality of program codes used for an autonomous driving mode are redundantly applied to at least two different control units. In doing so, the self-propelled motor vehicle is operated in an at least partially autonomous driving mode. In this mode, the functions directly needed to satisfy the passenger's wishes are ascertained and weighted corresponding to their relevance for satisfying the passenger's wishes. In so doing, the functions, or the scope of functions, are released depending on the achievement of a target achievement level.

Abstract: A self-driving motor vehicle including numerous control units and numerous program codes for controlling the functions of the autonomous driving and other functions of the self-driving vehicle. Numerous program codes used for an autonomous driving mode are applied redundantly to at least two different control units. The self-driving motor vehicle may then be operated in an at least a partially autonomous driving mode. In this mode, the functions directly needed for satisfying a passenger's desire are determined, and weighted with regard to their importance in fulfilling the passenger's desires. At least one function of a lower order is then shut off, if the available resources in functioning control units and/or the power level in the self-driving motor vehicle are insufficient to execute program code for executing this function of the lower order.

Abstract: Embodiments of the invention provide for a device and method for processing multi-channel audio signals, the multi-channel audio signals comprising at least a left channel, a right channel, and a center channel. Embodiments of the invention also provide for a non-transitory computer-readable storage medium having stored thereon instructions that when executed on a computer cause the computer to perform the method.

Abstract: A method of manufacturing a semiconductor device is described. A semiconductor substrate is provided. The semiconductor substrate includes a semiconductor substrate layer and a semiconductor device layer. The method includes transforming areas of the semiconductor device layer into dicing areas which can be removed by etching, and removing the semiconductor substrate layer and the dicing areas by using etching.

Abstract: A self-driving motor vehicle including numerous control units and numerous program codes for controlling the functions of the autonomous driving and other functions of the self-driving vehicle. Numerous program codes used for an autonomous driving mode are applied redundantly to at least two different control units. The self-driving motor vehicle may then be operated in an at least a partially autonomous driving mode. In this mode, the functions directly needed for satisfying a passenger's desire are determined, and weighted with regard to their importance in fulfilling the passenger's desires. At least one function of a lower order is then shut off, if the available resources in functioning control units and/or the power level in the self-driving motor vehicle are insufficient to execute program code for executing this function of the lower order.

Abstract: The disclosure provides a method for operating an automatically driving vehicle, wherein application instances are executed over several computational nodes, wherein recognized faults are reacted to by switching to redundant application instances and then reconfiguring the configuration to restore specified redundancy conditions and/or segregation conditions, wherein the vehicle is transitioned to a safe state using at least one failover apparatus when at least one specified redundancy condition and/or at least one segregation condition cannot be met by the reconfiguration, and/or a specified time for reconfiguration is exceeded, and/or an unrecoverable malfunction has been recognized, wherein the at least one failover apparatus plans an emergency trajectory using a trajectory planner, wherein sensor data are detected via separate signal lines and supplied to the at least one failover apparatus, and wherein control signals are generated and transmitted via separate control lines to an actuator system of the v

Abstract: The invention relates to a method for operating a self-propelled motor vehicle having a plurality of control units and a plurality of program codes for controlling the function of autonomous driving and possibly other functions of the self-propelled vehicle, wherein a plurality of program codes used for an autonomous driving mode are redundantly applied to at least two different control units. In doing so, the self-propelled motor vehicle is operated in an at least partially autonomous driving mode. In this mode, the functions directly needed to satisfy the passenger's wishes are ascertained and weighted corresponding to their relevance for satisfying the passenger's wishes. In so doing, the functions, or the scope of functions, are released depending on the achievement of a target achievement level.

Abstract: The subject-matter of the present invention is a method for reversibly releasing stem cells from bone marrow niches into peripheral blood and isolating these stem cells. Further, the present invention relates to stem cells obtained in this manner and their use in the medical treatment.

Abstract: The present invention provides a new fungal production system comprising a fungal host strain of Chrysosporium lucknowense wherein the endogenous cellulase secretion is less than 20% of the endogenous cellulase secretion of Chrysosporium lucknowense strain UV 18-25. Preferably, also the secretion of endogenous protease, endogenous ?-glucanase and endogenous cellobiohydrolase is less than 20% of the secretion of Chrysosporium lucknowense strain UV 18-25. Furthermore, fungal host strains are provided wherein several genes have been disrupted. According to another aspect of the invention a method for homologous and/or heterologous production of a pure protein with a purity of higher than 75%, comprising expressing a gene encoding said protein in the strains according to the invention have been described. Furthermore, a method for production of artificial protein mixes comprising expressing a gene encoding each of said proteins in a strain according to the invention have been disclosed.

Abstract: Provided are cells having an increased protein production characterized in that said cell comprises modified SUMOylation, a process for producing such a cell or expression system and the use of such a cell in producing a protein of interest.

Abstract: The invention provides, in one aspect, a system for recirculating ozonated liquid. The system includes a contactor including at least two inlets and at least two outlets. The contactor is in fluid communication with a first liquid source at a first contactor inlet and a second liquid source at a second contactor inlet, and the second contactor inlet receives gas that purges at least a portion of gas from liquid received at the first contactor inlet. The purged gas exits the contactor at a first contactor outlet. The contactor is in fluid communication with the second liquid source at a second contactor outlet, and the contactor drains at least a portion of the liquid in the contactor, the drained liquid exiting the contactor at the second contactor outlet. The contactor includes a third inlet in fluid communication with the first liquid source, the third inlet allowing the first liquid source to release liquid at an ambient pressure.

Abstract: Provided are cells having an increased protein production characterized in that said cell comprises modified SUMOylation, a process for producing such a cell or expression system and the use of such a cell in producing a protein of interest.

Abstract: The invention provides, in one aspect, a system for recirculating ozonated liquid. The system includes a contactor including at least two inlets and at least two outlets. The contactor is in fluid communication with a first liquid source at a first contactor inlet and a second liquid source at a second contactor inlet, and the second contactor inlet receives gas that purges at least a portion of gas from liquid received at the first contactor inlet. The purged gas exits the contactor at a first contactor outlet. The contactor is in fluid communication with the second liquid source at a second contactor outlet, and the contactor drains at least a portion of the liquid in the contactor, the drained liquid exiting the contactor at the second contactor outlet. The contactor includes a third inlet in fluid communication with the first liquid source, the third inlet allowing the first liquid source to release liquid at an ambient pressure.

Abstract: The invention provides, in one aspect, a system for recirculating ozonated liquid. The system includes a contactor including at least two inlets and at least two outlets. The contactor is in fluid communication with a first liquid source at a first contactor inlet and a second liquid source at a second contactor inlet, and the second contactor inlet receives gas that purges at least a portion of gas from liquid received at the first contactor inlet. The purged gas exits the contactor at a first contactor outlet. The contactor is in fluid communication with the second liquid source at a second contactor outlet, and the contactor drains at least a portion of the liquid in the contactor, the drained liquid exiting the contactor at the second contactor outlet. The contactor includes a third inlet in fluid communication with the first liquid source, the third inlet allowing the first liquid source to release liquid at an ambient pressure.

Abstract: The present invention provides a new fungal production system comprising a fungal host strain of Chrysosporium lucknowense wherein the endogenous cellulase secretion is less than 20% of the endogenous cellulase secretion of Chrysosporium lucknowense strain UV 18-25. Preferably, also the secretion of endogenous protease, endogenous ?-glucanase and endogenous cellobiohydrolase is less than 20% of the secretion of Chrysosporium lucknowense strain UV 18-25. Furthermore, fungal host strains are provided wherein several genes have been disrupted. According to another aspect of the invention a method for homologous and/or heterologous production of a pure protein with a purity of higher than 75%, comprising expressing a gene encoding said protein in the strains according to the invention have been described. Furthermore, a method for production of artificial protein mixes comprising expressing a gene encoding each of said proteins in a strain according to the invention have been disclosed.

Abstract: The invention provides, in one aspect, a system for recirculating ozonated liquid. The system includes a contactor including at least two inlets and at least two outlets. The contactor is in fluid communication with a first liquid source at a first contactor inlet and a second liquid source at a second contactor inlet, and the second contactor inlet receives gas that purges at least a portion of gas from liquid received at the first contactor inlet. The purged gas exits the contactor at a first contactor outlet. The contactor is in fluid communication with the second liquid source at a second contactor outlet, and the contactor drains at least a portion of the liquid in the contactor, the drained liquid exiting the contactor at the second contactor outlet. The contactor includes a third inlet in fluid communication with the first liquid source, the third inlet allowing the first liquid source to release liquid at an ambient pressure.

Abstract: The present invention provides a new fungal production system comprising a fungal host strain of Chrysosporium lucknowense wherein the endogenous cellulase secretion is less than 20% of the endogenous cellulase secretion of Chrysosporium lucknowense strain UV 18-25. Preferably, also the secretion of endogenous protease, endogenous ?-glucanase and endogenous cellobiohydrolase is less than 20% of the secretion of Chrysosporium lucknowense strain UV 18-25. Furthermore, fungal host strains are provided wherein several genes have been disrupted. According to another aspect of the invention a method for homologous and/or heterologous production of a pure protein with a purity of higher than 75%, comprising expressing a gene encoding said protein in the strains according to the invention have been described. Furthermore, a method for production of artificial protein mixes comprising expressing a gene encoding each of said proteins in a strain according to the invention have been disclosed.

Abstract: A surgical system for opening the lens capsule in an eye includes an application instrument introducible into the anterior chamber of the eye through an incision in the cornea and/or in the sclera. The application instrument has a contact body that is placeable against the anterior capsular wall of the lens capsule of the eye. Light provided by a light source for generating heat in a contact zone of the capsular wall contacting the contact body is appliable to the contact body. The heat has thermal energy that coagulates the biological tissue in the contact zone.

Abstract: A method of performing a capsulotomy comprises applying a light-absorbing agent to a lens capsule of an eye 1; illuminating the lens capsule using a first light beam and recording an image of the lens capsule using a camera 43; analyzing the recorded image and determining whether the light absorbing agent has been correctly applied to the lens capsule; if it is determined that the light absorbing agent has been correctly applied to the lens capsule, directing a shaped second light beam 19 onto a predetermined line on the lens capsule in order to modify a structure of a tissue of the lens capsule. The first light beam can be generated by defocusing the second light beam using a lens 37.