Abstract: The present disclosure provides a foam nasal dressing for topically administering an active agent to a nasal cavity and for absorbing fluid discharge. The foam nasal dressing comprises a foamed core portion and a foamed shell portion arranged such that the foamed core portion is at least partially disposed within the foamed shell portion. The foamed shell portion has a porosity of greater than 80% and comprises a first phase-separated polymer and an active agent. The foamed core portion comprises a second phase-separated polymer with the first and second phase-separated polymers being the same or different. The present disclosure also provides a method of forming the foam nasal dressing.

Abstract: The present disclosure provides a bioresorbable foam closure device for trans-nasally closing an opening in a base of a skull. The closure device comprises a phase-separated polymer. The device includes a stem portion having a proximal end and a distal end, and a head portion at the distal end of the stem portion. The closure device is deformed from a free shape to a constricted shape, inserted through a nasal cavity and into the opening, and released to at least partially revert back to the free shape such that the stem portion fills the opening and the head portion abuts cranium and dura to secure the closure device in position and seal the opening.

Abstract: The present disclosure provides a bioresorbable foam closure device for trans-nasally closing an opening in a base of a skull. The closure device comprises a phase-separated polymer having a porosity of greater than 80%. The device includes a stem portion having a proximal end and a distal end, and a head portion at the distal end of the stem portion. The closure device is deformed from a free shape to a constricted shape, inserted through a nasal cavity and into the opening, and released to at least partially revert back to the free shape such that the stem portion fills the opening and the head portion abuts cranium and dura to secure the closure device in position and seal the opening.

Abstract: A device for collecting bone fragments includes a housing (512) and a filter element (522) disposed in the housing. The filter element has a first end (524), a second end (526), and a sidewall (528) that defines an inner peripheral (530) and outer peripheral (532) surface and includes a plurality of filter apertures (534). The inner peripheral surface at least partially defines a collection chamber (536) for collection of a composition comprising bone fragments. The outer peripheral surface of the sidewall and the housing are spaced apart from one another to define an exterior radial volume (540). The filter element also has a proximal portion (535) adjacent the second end (526) which defines at least one drain aperture (555). The composition is acquired and collected in the collection chamber with the exterior radial volume providing a primary fluid communication path with a vacuum source and the at least one drain aperture providing a supplementary fluid communication path with the vacuum source.

Abstract: Systems and methods for deploying a stent within the frontal sinus. The stent includes flexible foam and film layers arranged in a stacked configuration and furled within a cartridge prior to deployment. The cartridge is removably coupled to an applicator device including an actuator. The film layer may include a polymer having a resilience sufficient to unfurl the stent and maintain patency of the frontal sinus opening. The flexible foam layer may have porosity of greater than 80%, and an active agent may be within the flexible foam layer. The flexible foam layer may be bioresorbable and the flexible film layer biocompatible and non-biodegradable. The stent may include first and second body portions with the first body portion independently unfurling from the second body portion to retain the stent within the frontal sinus. Contouring of the first and second body portions may facilitate ease with removal of the stent.

Abstract: The present disclosure provides a bioresorbable foam closure device for trans-nasally closing an opening in a base of a skull. The closure device comprises a phase-separated polymer having a porosity of greater than 80%. The device includes a stem portion having a proximal end and a distal end, and a head portion at the distal end of the stem portion. The closure device is deformed from a free shape to a constricted shape, inserted through a nasal cavity and into the opening, and released to at least partially revert back to the free shape such that the stem portion fills the opening and the head portion abuts cranium and dura to secure the closure device in position and seal the opening.

Abstract: A device for collecting and processing bone fragments comprises a housing and a filter element disposed in the housing. The filter element at least partially defines a collection chamber for the collection of a composition comprising bone fragments. An inlet cap is releasably coupled to either the housing or to the filter element and configured to receive the composition. The inlet cap includes a body, an inlet port extending from the body and configured to be coupled to a surgical tool, and a spout extending from the body opposite the inlet port. The spout includes an injection port extending into the collection chamber of the filter element. A outlet cap is releasably coupled to the housing and is configured to be coupled to a vacuum source.

Abstract: The present disclosure provides a foam nasal dressing for topically administering an active agent to a nasal cavity and for absorbing fluid discharge. The foam nasal dressing comprises a foamed core portion and a foamed shell portion arranged such that the foamed core portion is at least partially disposed within the foamed shell portion. The foamed shell portion has a porosity of greater than 80% and comprises a first phase-separated polymer and FIG. 1A an active agent. The foamed core portion comprises a second phase-separated polymer with the first and second phase-separated polymers being the same or different. The present disclosure also provides a method of forming the foam nasal dressing.