Abstract: The invention relates to a device for administering a liquid drop by drop, in particular an ophthalmic liquid. This administering device comprises a packaging filled with the liquid and an outflow channel for connecting to the packaging and comprising a perforation member at one end, which perforation member is received in a frame for mounting on the packaging. The invention further relates to an assembly of such an administering device and an outer packaging which comprises one or more receiving spaces for the administering device. The invention also relates to a method for manufacturing a frame for such an administering device. The invention also relates to a method for forming an administering device. The invention finally relates to a method for administering a liquid drop by drop.

Abstract: The invention relates to a device for administering a liquid drop by drop, in particular an ophthalmic liquid. This administering device comprises a packaging filled with the liquid and an outflow channel for connecting to the packaging and comprising a perforation member at one end, which perforation member is received in a frame for mounting on the packaging. The invention further relates to an assembly of such an administering device and an outer packaging which comprises one or more receiving spaces for the administering device. The invention also relates to a method for manufacturing a frame for such an administering device. The invention also relates to a method for forming an administering device. The invention finally relates to a method for administering a liquid drop by drop.

Abstract: The invention relates to a device for administering a liquid drop by drop. This administering device comprises a packaging filled with the liquid, an outflow channel with an administering opening, and means connected to the outflow channel for opening the packaging, wherein the opening means and the packaging are movable relative to each other. The device can have means for receiving the packaging, which receiving means can be adapted to fix the packaging, wherein the opening means are then movable relative to the receiving means. The opening means can conversely also be fixed relative to the receiving means, wherein the packaging is then movable in the receiving means. The opening means can be formed by a sharp outer end of the outflow channel.

Abstract: The invention relates to a device for administering a liquid drop by drop. This administering device comprises a packaging filled with the liquid, an outflow channel with an administering opening, and means connected to the outflow channel for opening the packaging, wherein the opening means and the packaging are movable relative to each other. The device can have means for receiving the packaging, which receiving means can be adapted to fix the packaging, wherein the opening means are then movable relative to the receiving means. The opening means can conversely also be fixed relative to the receiving means, wherein the packaging is then movable in the receiving means. The opening means can be formed by a sharp outer end of the outflow channel.

Abstract: A closed sterile bag system contains at least two separate compartments with communication between them temporarily blocked and with one of the compartments containing an erythrocyte sedimentation solution. The umbilical cord blood is collected and contacted with an anticoagulant whereupon the blockage is removed and the erythrocyte sedimentation solution is caused to contact the blood all within the closed sterile system.

Abstract: A closure assembly for a vial for a sterile drug comprises a body fitted with a sealable tube that has a seal that hermetically closes it on one end and that is in communication with the inside of the drug vial on the other end. The sterile drug can be reconstituted and/or diluted in an IV solution by means of sterile docking in a closed system. Via the tube on this closure assembly, the vial is connected to a component with a closed sealable tube, such as an IV solution container or a syringe by unsealing and joining the outer ends of the tubes to each other in a sterile docking procedure. If the drug needs reconstitution or dilution, a sterile fluid can first be introduced into the drug vial from the flexible container or from the syringe via the joined ends of the tubes. When the drug is dissolved, the solution can be aspirated to the flexible container or to the syringe. Subsequently, the tube connecting the vial and the component can be sealed and the seal can be cut.

Abstract: A syringe assembly having a syringe has an outlet opening and a tube having an inner end hermetically sealed over the outlet opening and an outer end. Thus any contents of the syringe can flow unimpeded via the outlet into the tube and vice versa. A seal hermetically closes the outer end of the tube. Such a syringe assembly is filled from a medical-liquid-holding container also having an outlet opening provided with a respective such tube whose outer end is similarly sealed. The syringe is filled by first unsealing and joining the outer ends of the tubes to each other in a sterile docking procedure, then aspirating the medicament through the unsealed and joined ends and resealing the tubes together, and finally cutting the tubes apart where they are sealed together to form two new seals on the tube outer ends.

Abstract: An aseptic solution for IV administration is prepard by thrusting a drug vial over a needle of a connector having a valve provided with a sterilizing air filter. In a first position of the valve, the communication to the IV container is blocked, but the vial is connected to the atmosphere through the sterilizing air filter to allow equalization of the atmospheric pressure with the pressure in the vial. In the second position, the communication with the filter is cutoff and the vial is connected to the IV container to allow IV solution to enter the vial and solution to be transferred between the vial and the IV container. In a final position, the ports of the valve are all blocked to close off the vial in which the sterile air is now trapped so that loss of the IV solution into the vial will be prevented.