Patents by Inventor Johannes Wilhelm Bigalke

Johannes Wilhelm Bigalke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Botulinum neurotoxin a protein receptor and uses thereof
    Patent number: 8476024
    Abstract: The invention relates to an isolated polypeptide of the luminal domain of synaptic vesicle glycoprotein 2C of Homo sapiens wherein at least 70 percent of the amino acid sequence is identical to the amino acid sequence of the SV2C of Homo sapiens. The polypeptide binds the HC fragment of botulinum neurotoxin A provided that the polypeptide is not the synaptic vesicle glycoprotein 2C of Homo sapiens.
    Type: Grant
    Filed: October 30, 2006
    Date of Patent: July 2, 2013
    Assignee: Toxogen GmbH
    Inventors: Stefan Mahrhold, Johannes Wilhelm Bigalke, Andreas Rummel, Thomas Binz
  • Botulinum Neurotoxin a Protein Receptor and Uses Thereof
    Publication number: 20090252722
    Abstract: The invention relates to a polypeptide comprising an amino acid sequence, at least 70 percent of which are identical to the amino acid sequence of the synaptic vesicle glycoprotein of homo sapiens. Said polypeptide binds the HC fragment of botulinum neurotoxin A provided that the polypeptide is not the synaptic vesicle glycoprotein 2C of homo sapiens.
    Type: Application
    Filed: October 30, 2006
    Publication date: October 8, 2009
    Inventors: Stefan Mahrhold, Johannes Wilhelm Bigalke, Andreas Rummel, Thomas Binz