Patents by Inventor Johannes Zuber

Johannes Zuber has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nucleic acid modification and identification method
    Patent number: 11859248
    Abstract: A method of identifying a polynucleic acid (PNA) is presented, including the steps of providing a PNA; modifying one or more nucleobases of the PNA by addition or removal of a hydrogen bonding partner, thereby altering the base pairing capacity of the one or more nucleobases; base pairing a complementary nucleic acid to the PNA, including base pairing to at least one modified nucleobase; identifying the sequence of the complementary nucleic acid at least at the position that is complementary to at least one modified nucleobase.
    Type: Grant
    Filed: February 18, 2022
    Date of Patent: January 2, 2024
    Assignee: IMBA—INSTITUT FÜR MOLEKULARE BIOTECHNOLOGIE GMBH
    Inventors: Stefan L. Ameres, Brian Reichholf, Veronika A. Herzog, Johannes Zuber, Matthias Muhar
  • NUCLEIC ACID MODIFICATION AND IDENTIFICATION METHOD
    Publication number: 20230054714
    Abstract: A method of identifying a polynucleic acid (PNA) is presented, including the steps of providing a PNA; modifying one or more nucleobases of the PNA by addition or removal of a hydrogen bonding partner, thereby altering the base pairing capacity of the one or more nucleobases; base pairing a complementary nucleic acid to the PNA, including base pairing to at least one modified nucleobase; identifying the sequence of the complementary nucleic acid at least at the position that is complementary to at least one modified nucleobase.
    Type: Application
    Filed: February 18, 2022
    Publication date: February 23, 2023
    Inventors: Stefan L. AMERES, Brian REICHHOLF, Veronika A. HERZOG, Johannes ZUBER, Matthias MUHAR
  • Nucleic acid modification and identification method
    Patent number: 11299779
    Abstract: A method of identifying a polynucleic acid (PNA) is presented, including the steps of providing a PNA; modifying one or more nucleobases of the PNA by addition or removal of a hydrogen bonding partner, thereby altering the base pairing capacity of the one or more nucleobases; base pairing a complementary nucleic acid to the PNA, including base pairing to at least one modified nucleobase; identifying the sequence of the complementary nucleic acid at least at the position that is complementary to at least one modified nucleobase.
    Type: Grant
    Filed: April 13, 2018
    Date of Patent: April 12, 2022
    Assignee: IMBA—INSIIIUT FÜR MOLEKULARE BIOTECHNOLOGIE GMBH
    Inventors: Stefan L. Ameres, Brian Reichholf, Veronika A. Herzog, Johannes Zuber, Matthias Muhar
  • Compositions and methods for treating leukemia
    Patent number: 10676484
    Abstract: The invention provides compositions, methods, and kits for the treatment of acute myeloid leukemia in a subject.
    Type: Grant
    Filed: October 17, 2017
    Date of Patent: June 9, 2020
    Assignees: Dana-Farber Cancer Institute, Inc., Cold Spring Harbor Institute
    Inventors: James Elliott Bradner, Johannes Zuber, Junwei Shi, Christopher R. Vakoc, Scott W. Lowe, Constantine S. Mitsiades
  • NUCLEIC ACID MODIFICATION AND IDENTIFICATION METHOD
    Publication number: 20190177785
    Abstract: A method of identifying a polynucleic acid (PNA) is presented, including the steps of providing a PNA; modifying one or more nucleobases of the PNA by addition or removal of a hydrogen bonding partner, thereby altering the base pairing capacity of the one or more nucleobases; base pairing a complementary nucleic acid to the PNA, including base pairing to at least one modified nucleobase; identifying the sequence of the complementary nucleic acid at least at the position that is complementary to at least one modified nucleobase.
    Type: Application
    Filed: April 13, 2018
    Publication date: June 13, 2019
    Inventors: Stefan L. AMERES, Brian REICHHOLF, Veronika A. HERZOG, Johannes ZUBER, Matthias MUHAR
  • COMPOSITIONS AND METHODS FOR TREATING LEUKEMIA
    Publication number: 20180222917
    Abstract: The invention provides compositions, methods, and kits for the treatment of acute myeloid leukemia in a subject.
    Type: Application
    Filed: October 17, 2017
    Publication date: August 9, 2018
    Inventors: James Elliott Bradner, Johannes Zuber, Junwei Shi, Christopher R. Vakoc, Scott W. Lowe, Constantine S. Mitsiades
  • Compositions and methods for treating leukemia
    Patent number: 9815849
    Abstract: The invention provides compositions, methods, and kits for the treatment of acute myeloid leukemia in a subject.
    Type: Grant
    Filed: July 3, 2013
    Date of Patent: November 14, 2017
    Assignees: Dana-Farber Cancer Institute, Inc., Cold Spring Harbor Laboratory
    Inventors: James Elliott Bradner, Johannes Zuber, Junwei Shi, Christopher R. Vakoc, Scott W. Lowe, Constantine S. Mitsiades
  • ENHANCED REPROGRAMMING TO IPS CELLS
    Publication number: 20170211048
    Abstract: The present invention concerns a method of preparing a population of iPS cells comprising reducing the amount and/or activity of one or more components of the CAF1 complex, and/or one or more components of the SUMO pathway, in a population of target cells, and (ii) optionally isolating the iPS cells from the target cell population.
    Type: Application
    Filed: July 23, 2015
    Publication date: July 27, 2017
    Inventors: Ulrich ELLING, Barbara HOPFGARTNER, Josef PENNINGER, Johannes ZUBER
  • Compositions and Methods for Treating Leukemia
    Publication number: 20140011862
    Abstract: The invention provides compositions, methods, and kits for the treatment of acute myeloid leukemia in a subject.
    Type: Application
    Filed: July 3, 2013
    Publication date: January 9, 2014
    Applicants: Cold Spring Harbor Laboratory, Dana-Farber Cancer Institute, Inc.
    Inventors: James Elliott Bradner, Johannes Zuber, Junwei Shi, Christopher R. Vakoc
  • Detection of differential gene expressions
    Publication number: 20030170625
    Abstract: The invention relates to a process for detecting differential gene expressions and new nucleic acid sequences that can be obtained by this process.
    Type: Application
    Filed: January 31, 2001
    Publication date: September 11, 2003
    Applicant: metaGen Gesellschaft fur Genomforschung mbH
    Inventors: Andre Rosenthal, Bernd Hinzmann, Reinhold Schaffer, Johannes Zuber, Oleg Tchernitsa, Martin Grips, Martin Hellriegel, Anne-Chantal Schmitz, Christine Sers