Abstract: A thermal control unit for delivering temperature-controlled fluid to one or more patient therapy devices (e.g. pads, blankets, etc.) that are in contact with a patient is disclosed. The thermal control unit allows multiple patient therapy devices to be fluidly coupled thereto and to individually monitor the temperatures, flow rates, and/or connections/disconnections of the patient therapy devices. A user interface enables a user to designate outlet ports to the therapy devices as active or inactive, and the control unit provides notifications to the user if any of the active ports experience an undesired condition, or if a patient therapy device is connected to an inactive port. The user interface further allows the user to designate one of multiple patient temperature probes as a primary probe. The primary probe is used to control the temperature of the fluid circulating through the control unit.

Abstract: An audio device, such as a headphone, can create, maintain and use secure data. The secure data can include an amount of time that the user has used the audio device and/or an amount of time allocated to the user. When the amount of time the user has used the audio device exceeds the amount of time allocated to the user, the audio device can stop emitting the audio. The secure data can also include a hearing profile of the user, which can uniquely identify the user. The secure data associated with the headphone can be encrypted to prevent tampering.

Abstract: An optically readable marker comprises a dash and two dots arranged in a pattern to allow detection of the marker, wherein the dash and dots are collinear, and wherein the dots are of the same size and shape and adjacent to each other. Multiple such optically readable markers may be combined into a composite marker, optionally with one element (i.e. a dash or a dot of the marker) being at least partially shared between two or more markers.

Abstract: Disclosed are methods, libraries, and samples for quantifying a target analyte in a laboratory sample including the target analyte. The methods typically include the step of estimating the amount of the target analyte in the laboratory sample from mass spectrometric data including signal intensities for the target analyte and one or more internal standards, where the mass spectrometric data are an output of a mass spectrometric analysis of a target sample produced from the laboratory sample and a predetermined amount of the one or more internal standards. The present disclosure also provides a method for analyte quantification. The method comprises adding one or more calibrators to a sample comprising one or more analytes; applying mass spectrometry (MS) to the sample; and using a trained machine learning model to determine an absolute concentration of the one or more analytes.

Abstract: Aspects include a cryptographic hardware security module having a secure embedded heat pipe and methods for assembling the same. The cryptographic hardware security module can include a printed circuit board having one or more components. The cryptographic hardware security module can further include an encapsulation structure having a top can and a bottom can. The top can is fixed to a first surface of the printed circuit board and the bottom can is fixed to second surface of the printed circuit board opposite the first surface. A heat pipe is positioned between the top can and the component. The heat pipe includes two or more 180-degree bends. A portion of the heat pipe extends beyond a secure region of the encapsulation structure.

Abstract: Antibodies that bind ICOS (Inducible T cell Co-Stimulator). Therapeutic use of anti-ICOS antibodies for modulating the ratio between regulatory T cells and effector T cells, to stimulate the immune system of patients, including use in treating cancers. Methods of producing anti-ICOS antibodies, including species cross-reactive antibodies, using transgenic knock-out mice.

Abstract: Systems and methods disclosed herein are related to an intelligent UI element selection system using eye-gaze technology. In some example aspects, a UI element selection zone may be determined. The selection zone may be defined as an area surrounding a boundary of the UI element. Gaze input may be received and the gaze input may be compared with the selection zone to determine an intent of the user. The gaze input may comprise one or more gaze locations. Each gaze location may be assigned a value according to its proximity to the UI element and/or its relation to the UI element's selection zone. Each UI element may be assigned a threshold. If the aggregated value of gaze input is equal to or greater than the threshold for the UI element, then the UI element may be selected.

Abstract: A multi-wheeled vehicle (e.g., bicycle, tricycle, quadricycle) frame includes a head tube, a seat tube, a top tube, a brace tube, and a down tube. The seat tube is disposed away from the head tube. The top tube is pivotally coupled to the seat tube and pivotally coupled to the head tube. The brace tube is pivotally coupled to the seat tube and pivotally coupled to the head tube. The down tube is pivotally coupled to the seat tube and pivotally coupled to the head tube.

Abstract: Presented herein are techniques that make use of objective measurements obtained in response to acoustic stimulation signals. More specifically, at least one measure of outer hair cell function and at least one measure of auditory nerve function are obtained from a tonotopic region of an inner ear of a recipient of a hearing prosthesis. The at least one measure of auditory nerve function and the least one measure of outer hair cell function are then analyzed relative to one another.

Abstract: Described are systems, devices, and methods which related to various aspects of assays for detecting and/or determining a measure of the concentration of analyte molecules or particles in a sample fluid. In some cases, the systems employ an assay consumable comprising a plurality of assay sites. The systems, devices, and/or methods, in some cases, are automated. In some cases, the systems, devices, and/or methods relate to inserting a plurality of beads into assay sites, sealing assay sites, imaging assay sites, or the like.

Abstract: A system and method for enhancing a database to thereby determine asset basis in a computerized accounting system, the method includes receiving basic transaction information relating to an asset, the basis transaction information including Real Date, As of Date, Journal ID, Payee ID, and Transaction ID, receiving transaction type information indicating at least one transaction type selected from Return of Capital, Short Sale, Close Short Sale, Transfer Out, Transfer In, Bought, Tax Basis Adjustment, Tax and Cost Basis Adjustment, and/or Sold, receiving additional transaction specific data, the transaction specific data being defined by the transaction type based on at least one rule, building a data matrix of required values for determining basis of the asset based on the additional transaction specific data, the transaction type information, and the basic transaction information, and determining at least one of a market value basis, a cost basis, and a tax basis for the asset based on the transaction type i

Abstract: A handheld vacuum cleaner includes a dirt separator. The dirt separator includes a chamber having an inlet through which dirt-laden fluid enters and an outlet through which cleansed fluid exits the chamber. A disc located at the outlet rotates about a rotational axis and comprises holes through which the cleansed fluid passes.

Abstract: Methods and devices are provided for simultaneously amplifying a plurality of sample wells for a predetermined amount of amplification, detecting whether amplification has occurred in a first set of the wells, amplifying for an additional amount of amplification and detecting whether amplification has occurred in a second set of the wells. Methods are also provided for analyzing a target nucleic acid sequence using melt curves that were generated in a plurality of amplification cycles.

Abstract: Optionally, a plurality of spacers 228 is arranged between the planar surface 120 of the interfacing arrangement 114 (or the top horizontal arm) and the seat arrangement 102, for permanently raising the seat arrangement 102 with respect to the interfacing arrangement 114. The spacers 228 can be implemented as rectangular or cylindrical solid blocks that can be fabricated from plastics materials, metals, metal alloys, polymers, ceramics, wood, composites and so forth. The spacers 228 can be fixed between the seat arrangement 102 and the top planar surface 120 of the top horizontal arm of the interfacing arrangement 114 such that height of the seat arrangement 102 relative to the footrest arrangement 116 is raised. For example, a plurality of metallic spacers is fixed between the seat arrangement 102 and the interface arrangement by a technician such as by welding the metallic spacers between the seat arrangement 102 and the interface arrangement.

Abstract: An assembly for retaining a pressure jacket (134) and a syringe (132) on a fluid injector, the assembly including a base plate (1902) comprising a body (1904); at least a first retaining arm (1910a) and a second retaining arm (1910b) operatively mounted on the body of the base plate, the first retaining arm having a first retaining surface at a distal end thereof and the second retaining arm having a second retaining surface at a distal end thereof, wherein the first retaining surface and the second retaining surface are configured for abutting a distal surface of at least one of the pressure jacket and the syringe; a linkage assembly operatively connected to at least one of the first retaining arm and the second retaining arm, wherein the linkage assembly is configured to move at least one of the first retaining arm and the second retaining arm between at least a first open position and a closed position.

Abstract: A wearable device may be used to perform a health or medical assessment of a user. The wearable device may detect user movements of the user. The wearable device generates signal data representing the user movements. The signal data is input into a model to identify a feature set. The feature set is converted into a score that corresponds to a medical condition of the user.

Abstract: Introduced here is a wearable audio system including modular ear-cup and ear-bud that can be attached and detached to the user together, or independently of each other. Further, the modular ear-cup and ear-bud can operate together, or independently of each other. The wearable audio system can perform active noise cancellation by measuring noise inside the ear-cup and/or the ear-bud, computing the noise canceling sound, and forwarding the noise canceling sound to a speaker inside the ear-cup and/or the ear-bud. The wearable audio system can be wirelessly charged while operating, thus allowing the user to continuously listen to music more than previously possible. The wearable audio system can optimize power consumption by redistributing power intensive tasks to power sources with the highest amount of power. Further, the ambient sound outside the ear-cup can be measured and played by the speakers in the earbud allowing the user to hear the surrounding environment.

Abstract: Systems and methods are provided for cleaning surfaces of a workpiece. The system includes a housing defining an enclosure, a holding structure within the enclosure that is configured to support a workpiece, a first powder removal device that is configured to propel a first media toward the holding structure such that the first media contacts the workpiece while the workpiece is supported by the holding structure, a first sensing device that is configured to detect surface characteristics of the workpiece while the workpiece is supported by the holding structure, and a controller configured to, by a processor: detect a powder material on a surface of the workpiece based on the surface characteristics, and selectively operate the first powder removal device to remove the powder material from the surface with the first media while the workpiece is supported by the holding structure.

Abstract: A system and method for providing video conferencing are described herein. Original video streams from one or more cameras are sampled to form downscaled versions of the video stream. The downscaled version is analyzed to find regions of interest and generate metadata describing aspects of the regions of interest, including a region that includes a preferred speaker and the best view of each participant present together in the video conference. Cropping instructions are generated from the metadata, and portions of the original video stream are removed to form a set of presentation views for each participant, including the preferred speaker. The set of presentation views is stitched together to form a composite display for each participant viewing the stream remotely.

Abstract: A method including determining historical user data associated with an event occurring on a wearable device, determining a probability of interacting with an object on a display of the wearable device based on the historical user data, scaling a hitbox associated with the object to form a scaled hitbox, detecting a user input based on an eye tracking being within the scaled hitbox, and in response to detecting the user input, initiating an action corresponding to the object.